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13 Cards in this Set

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HERPES SIMPLEX VIRUS (HSV)

Type 1: cold sores, fever blisters, whitlow

Type 2: genital
Enveloped
Icosahedral
Genome: DNA
Recurrent ulcerative disease
HERPES SIMPLEX VIRUS (HSV)

TYPE 1
INFECTS: mucous membranes, skin of lips, cheeks, throat, gums

Latent infection with reactivation
Ulcerated lesions, infectious

Transmission: fomites, direct contact
PATHOLOGY: LOOK UP
HERPES SIMPLEX VIRUS (HSV)

TYPE 2
Genital Herpes
INFECTS: penis and surrounding areas; Labia minora/majora (can go unnoticed); Perianal region
Latent infection with reactivation
Ulcerated lesions, infectious

Transmission: STD, oral
HERPES SIMPLEX VIRUS (HSV)

DIAGNOSIS and TREATMENT
DIAGNOSIS
Virus easily grown (culture), subtype identified by monoclonal antibodies
TREATMENT: No cure, reduce duration of secondary lesions with nucleotide analog drugs
HUMAN PAPILLOMA VIRUS (HPV)
Naked virus
Icosahedral
Genome: ?
60 Different strains!

Cause warts
Warts: benign growth of the epithelium of the skin or mucous membrane (no inflammation)
HUMAN PAPILLOMA VIRUS (HPV)

Warts
1/2
SEED (fingers/toes)
PLANTAR (feet)
FLAT (trunk/face/elbow/knees)
EXTERNAL GENITILIA

Symptoms: Itch, painless
HUMAN PAPILLOMA VIRUS (HPV)

Warts
2/2
Transmission: direct contact, fomites, childbirth, STD, endogenous (spread; ie barefoot)

Treatment: surgical, freeze, burn, laser, caustic chemicals
Pathology: Virus enters the skin->infects epithelial cells->epi cells proliferate (grow and divide)
POXVIRUSES
Enveloped
Genome DNA
Proteins that interferon, complement and inflammation.

STAGES:
LESION STAGES (small pox):
Macule
Papule
Vesicle
Pustule (pox)
VARICELLA-ZOSTER VIRUS

CHICKENPOX
(related to herpes virus)
Highly Contagious
1/2
Symptoms: Fever, common cold-like, rash (with stages)
Transmission: Aerosol
Treatment: fluids, rest
Vaccine: Live, attenuated virus, Varivax (children)
Zostavax (elderly)
VARICELLA-ZOSTER VIRUS

CHICKENPOX
(related to herpes virus)
Highly Contagious
2/2
Pathology: virus infects mucous membrane of the respiratory tract->inflammation->cough, sneeze->Viremia: liver, spleen, lymph nodes, skin-> virus infects skin->inflammation->rash
VARICELLA-ZOSTER VIRUS

ZOSTER (Shingles)
Reactivation of latent viral infection.
Sympt: Pain, itch, rash, blisters

Transmission: Endogenous (shingles)
Can spread to anyone who doesn't have immunity (reactivation of virus they already have)
MORBILLIVIRUS

RUBEOLA: Measles
Enveloped, helical nucleocapsid
Genome: RNA
Contagious
1/2
Symptoms: Fever, runny nose, malaise, diffuse rash, Koplik's spots.
Transmission: Aerosol, Droplet nuclei
MORBILLIVIRUS

RUBEOLA: Measles
Enveloped, helical nucleocapsid
Genome: RNA
Contagious
2/2
Pathology: Virus infects mucous membrane of resp. tract->inflammation->fever, runny nose, malaise>Viremia: conjunctiva, urinary tract, lymphatics, CNS, skin rash
Sign/symptoms 8-12 days after exposure
Complication: secondary bacterial infections