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15 Cards in this Set
- Front
- Back
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glomerular endothelial cells, loc, feat and fcn
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afferent and efferent arterioles in renal corpuscle
-fenestrated endothelium -contributes to synthesis of glomerular filtration barrier |
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podocytes, loc, feat, and fcn
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visceral layer of bowman's capsule in renal corpuscle
-primary and secondary processes -contribute to synthesis of glomerular filtration barrier |
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squamous epithelial cells, loc, feat, and fcn
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parietal layer of bowman's capsule
-lines the urinary space |
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intraglomerular mesangial cells, loc, feat, and fcn
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within renal corpuscle, between glomerular capillary loops
-modified sm muscle cells -supports the glomerulus -phagocytic to clean filtration barrier -receptors for angiotensin II and ANP--tubuloglomerular feedback |
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extraglomerular mesangial cells
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part of the juxtaglomerular (JG) apparatus, but not associated w/glomerular capillaries
-modified sm muscle cells -fcn is not known (they may be APUD cells or stem cells) |
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juxtaglomerular cells (JG Cells)
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JC apparatus in the tunica media of afferent and efferent arterioles
-modified sm muscle cells or myoepithelial cells -synthesize and secrete renin, thus initiation of vasoconstriction via the renin-angiotensin system -may contain angiotensin I and II |
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macula densa cells (cuboidal or columnar epithelial cells)
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macula densa of JG apparatus, specifically in part of the wall of the distal convoluted tubule over the vascular pole
-monitors urine volume and conc. -paracrine signalling to stimulate JG cells to secrete renin |
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proximal tubule cells
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proximal tubule: cells vary somewhat in character depending on region of tubule, S1 reg. is most proximal
-may appear as low or tall cuboidal -specialized for resorption, mostly occurs in S1 -extensive microvilli, apical caveolae, basal infoldings, numerous mitochondria, Na pumps, cotransporters in membranes -active endosomal and lysosomal compartments -secrete dihydroxycholecalciferol |
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squamous cells in loop of henle
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type I cells located in cortical nephrons, types II, III, and IV in juxtamedullary nephrons
-cells in descending limb are highly permeable to water, urea, and ions (Na, Cl) -cells in ascending limb are less permeable -contribute to the counter current multiplier function of the nephron |
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distal tubule cells (low cuboidal)
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cells vary somewhat in morphology depending on location
-cells not permeable to water or urea -can actively transport Na and Cl -apical nuclei, less microvilli, and mitochondria than in proximal tubule |
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principal cell (light cell)
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collecting ducts: the most prevalent cell in the largest of the collecting ducts (medullary and papillary)
-secrete K+, reabsorb Na -impermeable to water unless ADH is present -apical nuclei, few microvilli, few mito |
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intercalated (dark cell)
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cortical collecting duct and to a lesser extend medullary collecting ducts
-active transport of H+ -impermeable to water unless ADH is present -abundant mito, many apical vesicles |
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endothelium of peritubular capillary network
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capillaries from efferent arterioles of cortical nephrons
-synthesize and secrete erythropoietin |
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endothelium of vasa recta
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capillaries from efferent arterioles of juxtamedullary nephrons
-permeable to water and salts -fcns in counter current exchange to maintain osmotic gradients of the interstitial space around the vasa recta and collecting ducts |
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transitional epithelium
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kidney: renal calyces
ureters, urinary bladder, portions of urethra -urinary epithelium is multi-layered -top layer as dome cells |
