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13 Cards in this Set
- Front
- Back
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The 3 drug classes of Oral Antidiabetic Agents |
Sulphonylureas (gliclazides and glyburides) Biguanides (Metformin) Thiazolidinediones |
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Action of Biguanides (Metformin) |
Increase insulin sensitivity (causing glucose to store as glycogen in the liver) Increase glucose uptake in tissues Inhibits the breakdown of glycogen into glucose (so that glucose isn't released into the blood)
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Contraindications to Biguanides (Metformin) |
Liver and renal dysfunction |
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Side effects of Biguanides (Metformin) |
GI upset Anorexia Lactic acidosis |
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Action of Sulphonylureas |
Stimulate the B cells in the pancreas to secrete insulin |
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Side effects of Sulphonylureas |
Hypoglycemia Weight gain |
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Action of Thiazolidinediones |
Increases insulin sensitivity (which increases glucose uptake into tissues) Inhibits the release of free fatty acids in adipose tissue |
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Side effects of Thiazolidinediones |
Anaemia CHF Peripheral edema Fractures |
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Contraindications to Thiazolidinediones |
Liver failure CHF |
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Rapid-acting Insulin Mnemonic |
"15 minutes feels like an HOUR during 3 rapid responses" 15 min, 1 hr, 3 hr |
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Short-Acting Insulin (Regular Insulin) Mnemonic |
"Short-staffed nurses went from 30 patients to (2) 8 patients" 30 min, 2 hr, 8 hrs |
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Intermediate-acting Insulin Mnemonic |
"Nurses play hero to (2) 8 16 year olds"
2 hr, 8 hr, 16 hr |
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Long-acting Insulin |
Onset: 2 hrs No peak Duration: 24 hrs |
