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26 Cards in this Set

  • Front
  • Back

Bacteria

- circular DNA


- cell wall contains peptidoglycan


- reproduce by binary fission


- use organic chemicals, inorganic chemicals, or photosynthesis for energy (most diverse)

Viruses

- acellular


- consist of DNA OR RNA


- innermost layer: DNA or RNA


- inner layer: protein coat


- outer layer: envelope (optional)


- infectious but not alive

Fungi

- chitin walls


- use organic chemicals for energy


- mold and mushrooms


- yeasts are unicellular


- absorbers

Protozoa

- usually unicellular


- may be motile via pseudopods, cilia, or flagella

Helminths

- worms classified as a parasite


- live and reproduce from host

Algae

- cellulose cell walls


- use photosynthesis for energy


- produce molecular oxygen and organic compounds


- green from chlorophyll


- cause few medical problems

Louis Pasteur

- Germ theory: idea that microbes can be the cause of some illnesses


- conducted research in immunology (rabies vaccine)

Robert Hooke

- 1665


- reported that living things were composed of little cells


- developed compound microscope


- Hooke's Law

Antoni Van Leeuwenhoek

- 1673-1723


- described live microbes that he observed in teeth scrapings, rain water, and peppercorn infusions


- first to see live microbes using a hand-held simple microscope



Rudolf Virchow

- 1858


- Cell theory: all organisms are composed of cells and come from parent cells (biogenesis)

Spontaneous generation

living organisms arise from non-living matter (a "vital force" forms life)

Spontaneous Generation or Biogenesis?

1668


- Francis Redi filled six jars with decaying meet


- Disproved spontaneous generation from maggots




1745


- put boiled nutrient brother into covered flasks


- microbes do not come from spontaneous generation




1765


- boiled nutrients in flasks and sealed = no microbial growth




1861


- Louis Pasteur demonstrated that microorganisms are present in the air

Theory of Biogenesis

Pasteur's S-shaped flask kept microbes out but let air in


- disproved spontaneous generation for microbes

Louis Pasteur


Fermentation and Pasteurization

Microbes are responsible for fermentation and spoilage of food



Joseph Lister

First to use chemical antiseptics in surgery

Robert Koch

- fist proof that a particular bacteria can cause a disease (anthrax, TB)


- first solid proof of germ theory



Edward Jenner

- 1796


- used cowpox virus to protect from smallpox

Jenner Stems

- Father of immunology

Birth of Modern Chemotherapy

- treatment with chemicals in chemotherapy


- use of antibiotics to kill microbes


- penicillin was tested clinically and mass produced

Paul Ehrlich

- invented the precursor technique to gram staining


- antimicrobial chemotherapy

Modern Development in Microbiology

- immunology: study of immunity


- Rebecca Lancefield (1993): use of immunology to identify bacteria


- recombinant DNA is DNA made from two different sources

Elie Metchnikoff

- discovered the role of white blood cells in fighting infection


- noble prize for phagocytes

Selman Waksman

- streptomycin: first antibiotic effective against TB

Oswald Avery, Colin MacLeod, Maclyn McCarty

- 1944


- showed that DNA was the stuff of genes

Jim Watson and Francis Crick

- 1953


- puzzled out the structure of DNA

Nathans, Smith, and Arber

- developed way to cut and snip DNA with sticky ends for genetic engineering