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13 Cards in this Set

  • Front
  • Back
APC
colorectal cancer, associated with FAP
BRCA
brast and ovarian cancer, DNA repair protein
CPD4/SMAD4
pancreatic cancer. DPC - deleted in pancreatic cancer
DCC
colon cancer - DCC - deleted in colon cancer
MEN1
men type 1.
NF1
neurofibromatosis 1, RAS GTPase activated protein (neurofibromin)
NF2
neurofibromatosis 2, Merlin (schwannomin) protein
p16
melanoma. cyclic dependent kinase inhibitor 2a
p53
most human cancer, Lu-Fraumeni syndrome. transcription factor for p21, normally blocks G1 to S phase
Rb
retinoblastoma, osteosarcoma
TSC
tuberous sclerosis. 1: hamartin protein. 2: tuberin protein
VHL
von Hippel-Lindau dz. inhibits hypoxia inducible factor la
WT
wilm's tumor. nephroblastoma