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36 Cards in this Set

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Monogenea

-fish parasites, not in humans


--every body part has a different kind


-mostly ectoparasites


-haptor:posterior large muscular structure with spokes to stick onto surface of fish


-haptor irritates skin, fish produces mucous, feeds off mucous


-Feeding Stations: smaller fish eating parasites off larger fish


-Subclasses: Monopisthocotylea and Polypisthocotylea

Monopisthocotylea

Monogenea subtype


-Single posterior haptor


-Ectoparasites only


-Direct Lifecycle (No mollusk intermediate)


-Species in fish gills survive more -> trending towards endoparasites

Polypisthocotylea

Monogenea subtype


-Complex of multiple haptors that twist and tear flesh aggressively == more mucous


-Species that live on wall of frog urinary bladder,


-->eggs washed out with urine, hatch onchomiracidium


-->onchomiracidium are livae with hooks and cilia to swim


-->crawls into urinary bladder of frog/tadpole and matures


==>becoming ectoparasite

Aspidobothrea

-Freshwater clam parasites that aren't in humans


-live in pericardium of clam


-entire bottom surface == attachment organs to hold on as heart beats




-eggs hatch in pericardium and exit through intestine ==> Cotylocidium


-Cotylocidium enter next clam through gills


-Clams occasionally eaten by turtles


-->parasites survive in their small intestine




Significants: Trematodes living in mollusks and vertebrate





Digenea

Operculum = lid on egg


General Lifecycle:


-Egg


-Miracidium = covered in cilia, hatches from egg and swims randomly until chem signal from mollusk. Impacts surface->digestive enzymes->loses cilia and crawls through hole


-Sporocyst = sac containing internal subunits called "daughter sporocysts", which form identical "redia"


-Redia = break out and migrate in different directions. Stop close to skin. Divide internally to form "cercaria"


-Cercaria = break out of hole in redia and penetrate skin. Have tails like mini-trematodes. Penetrate something definitive host likes and form "metacercaria"


-metacercaria live in paratenic host


-Adult = lay eggs

Clonorchis sinensis

A Distome


TL;DR: liver problems in mammals in Asia from fish/shrimp


Host: humans, mink, pigs, dogs, cats, rats, camels, tigers


Life-cycle:


-human ingests metacercara in fish/shrimp


-intestine->bile duct->liver


-spines irritate liver => fibrotic response (fluke eats this


-Eggs dumped into bile duct


-Eggs containing miracidium defecated


-gets into water with mollusk


-cercaria infect shrimp/fish




ppp: 1 month




Symptoms:


-Liver enlargement


-eggs/worms forming nuclei of gallstones


-Thickening of bile ducts due to fibrosis


-Jaundice


-bile duct cancer




Zoogeographyb: ~Asia (14% Honk Kong)

Clornorchis-like trematodes

Distomes


TL;DR: heterophyids are smallest distomes. Live in small intestine. Can chew into blood thru villi -> heart attacks.


-Smallest of trematodes


Hosts: humans and other fish-eating animals


-Small intestine (Not Liver)


-So small, they sometimes cut into villi and get sucked into blood stream, carried to random places, 16% heart attacks in phillipines

Paragonimus westermani

A Distome




TL;DR: Brown streaks in sputum. Lung parasite in from crustaceans.Eating guinea pigs in Peru/Ecuador. Mistaken for TB/pneumonia




-Very large, important in USA**


-Mistaken for tuberculosis, pneumonia


-Can be caught by eating guinea pigs in Ecuador/Peru


Host: humans, dogs, cats, rodents pigs


Life-Cycle:


-adults in lung


-eggs coughed up as masses of brown streaks in sputum


-If sputum gets in water and mollusc, normal digenea life-cycle happens


-cercaria penetrate various crustaceans


-humans eat crustaceans


-small intestine -> blood -> lungs




PP: 20 years




Symptoms:


-eggs can form pseudotubercles


-brown streaks in sputum


-chest symptoms


-breathing difficulty


-chronic cough


-bloody sputum


-mistaken for TB/pneumonia




Zoogeography: Asia, Oceania (Australia), Central/South America




Diagnosis: flukes found on biopsy of x-ray detected tubercles

Fasciola hepatica

(liver rot disease) A Distome, fasciolid complex


TL;DR: Like C. sinensis, but metacercaria on aquatic plants. Humans and livestock.




Host: humans and livestock


Life-Cycle:


-adults lay eggs in liver


-bile ducts -> defecated out


-normal digenea life-cycle


-encysts as metacercaria on aquatic plants (like seaweed)


-plant eaten by human


-gets to liver through bile duct




Symptoms:


-pipestem(portal vein) fibrosis


-cirrhosis


-jaundice


-liver necrosis




Zoogeography: Europe, northern Africa, Cuba, SA



Fasciola gigantica

A Distome, fasciolid complex


TL;DR: more in sheep than humans




Host: sheep, some human cases


PPP: 40 days


Zoogeography: Africa, indo-China, Uzbeck Republic, Central Asia





Fasciola jacksoni

A Distome, fasciolid complex


TL;DR: elephants




Host: African Elephants


Symptoms:


-Can block bile duct:


-->anemia, weight loss, edema, death

Fascioloides magna

A Distome, fasciolid complex


TL;DR: swamp butterflies. Large. Cattle and Deer(stunts growth/antlers/reproduction).




-very large, twice size of quarter


-Swamp Butterflies: deep-fried in cornmeal coating and eaten like hush-puppies in SouthEastern US


Life-cycle:


-lives in liver parenchyma, response is calcareous cyst


-excretory system produces lots of melanin


Hosts: common in US Cattle (including in Taos), and in Deer and Elk


Symptoms:


Cattle:


-very severe


Deer and Elk:


-stunts growth in body and antlers, lower reproductive success



Fasciolopsis buski

A Distome, fasciolid complex


TL;DR: encysts on underwater plants, big flukes, metabolic byproducts in blood stream can be lethal.




-Very large, unbranched ceca


Hosts: humans and pigs


Life-Cycle:


-eggs take 7 weeks to hatch (a long time)


-cercaria encyst on underwater vegetation


-excyst in small intestine


PPP: 3 months


Symptoms:


-hemorrhage


-chronic diarrhea


-can be lethal: flukes are so big their byproducts can be passed into blood stream at sites of hemorrhage/irritation


Prevention: rinse veggies, dont use night soil

Nanophytes salmonicola

A Distome (salmon poisoning fluke of dogs)


TL;DR: contains neorickettsia hyperparasyte that kills dogs. Present in salmon. 10% lethal to dogs. Depresion, diahrrea, eye pus, etc.




-Not a problem itself, but it carries a smaller parasite that is (Neorickettsia helminthoeca)


Hosts: humans, dogs, cats, rats


Life-cycle:


-definitive host ingests undercooked salmon


-adults live in small intestine, eggs defecated


-normal digenea life-cycle


-cercaria infect salmon, metacercaria in muscle


(other fish species can also be infected, primarily salmon)




PPP: 4-6 days (dogs)




Symptoms:


(dogs):


-10% lethal


-depression


-loss of appetite


-facial swelling


-eye pus/discharge


-fever


-vomiting


-diarrhea


(humans): not lethal


Zoogeography: fast moving streams


Prevention: cook mollusks/fish thoroughly





Dicrocoelium dendriticum

A Distome (Lancet Fluke)


TL;DR: Snail->slimeball->ants->farm animal liver




-shaped like surgical lancet


-Thrives on land


Hosts: sheep, goats, cattle, pigs


Life-cycle:


-Adults live in liver


-bile duct -> defecate eggs


-snail eats poop


-cercaria move to slime gland


-form "slime ball" containing 500 cercaria


-ants cary to colony and feast on slime ball


-cercaria migrate to nerve ganglia controling mandible and form metacercaria


-->makes is to mandible can't open under 60 F


-->temp drops at night time = ants get stuck chomping on leaves/grass


-sheep eats ant/grass next morning


-liver through bile duct


-humans can get this by eating raw sheep liver (a delicacy in some places)




Zoogeography: Russia, Europe, Asia, North America

Haematoloechus medioplexus

(frog lung fluke) A Distome


TL;DR: The dragonfly one in frog lungs.




-rare in humans, kids have to eat a dragonfly


Host: frogs


Life-cycle:


-adults in lungs


-frogs defecate eggs into water


-normal digenea lifecycle


-cercaria swim into anus of dragonfly larvae


-->process aided by water being sucked into anal gills


-form metacercaria in rectal wall


-frog eats adult dragonfly



Prosthogonimus macrorchis

(oviduct fluke of birds) A Distome


TL;DR: The dragonfly one in bird oviducts.




-rare in humans, kids have to eat a dragonfly


Hosts: chickens, ducks, pheasants, crows, english sparrows


Life-cycle:


-Adults in bird oviducts


-->not enough inflammation to make sterile


-eggs get caught up in poop and defecated


-normal digenea lifecycle


-cercaria go into anus of dragonfly larvae


-bird eats adult dragonfly


-migrates into oviduct if female (defecated out if male)

Clinostomum companatum

A Distome


TL;DR: The bird esophagus one. Very rare laryngitis in humans. Paratenic= fish.




-rare in humans


Hosts: birds that eat freshwater fish, 3 cases in humans


Life-cycle:


-Adults in esophagus of bird


-bird cough up eggs


-normal digenea lifecycle


-cercaria encyst in fish muscle


-birds eat fish


PPP: 3 days


PP: 2 weeks


Symptoms: laryngitis in humans


Zoogeography: woman and 3 males in Japan, Israeli patient



Plagioporus sinitsini

A Distome


TL;DR: the fish one where the sporocyst doesn't break, and the first mollusk is the only intermediate. Humans have to put mollusk in mouth. Rare.




-rare in humans, have to put mollusk in mouth


Hosts: fish


Life-cycle:


-adults in fish gallbladder


-eggs defecate out


-snail eats poop


-UNUSUAL LIFE-CYCLE: sporocyst doesnt break. Contains metacercaria. No second intermediate.

Gorgodera amplicava

A Distome


TL;DR: Frog bladder -> fingernail clam -> snails, crayfish, and tadpoles.Rare in humans.




-rare in humans


-adults use large ventral sucker to hold onto urinary bladder




Host: frogs


Life-cycle:


-adults hold onto wall of urinary bladder


-eggs excreted


-miracidium penetrate fingernail clams, continue with normal digenea lifecycle


-cercaria penetrate lots of different snails, crayfish, and tadpoles


-frog eats paratenic host


-moves to urinary bladder

Characteristics of Echinostomes

-Two muscular lobes w/ sharp hooks around mouth


-->grind against each other to grind up tissue


-lots of pathology in humans


-intermediates: snails, shellfish, oysters


-many species in small intestine


-use lobes to eat a hole down into the small intestine


Zoogeography: all over, including New York


Symptoms:


-inflammatory lesions in intestines


-intestinal colic


-diarrhea


-in children: diarrhea, abd pain, anemia, edema



Echonostoma revolutum

An Echinostome


-humans get this by eating crayfish


-can infect and kill parasites in abnormal host


-good for biological control like cotylurus

Characteristics of Amphistomes

-Ventral sucker that is posterior, rather than in middle


-rarely transferred to humans by lifecycle involving it living on amphibians


-Normal digenea lifecycle, except:


-->cercaria encyst on frog skin


-->frog sheds skin and eats it


-->adults reside in rectum




-humans can pick up by eating frog legs

Gastrodiscoides hominis

An Amphistome


TL;DR: that amphistome in rats, pigs, and rhesus monkeys. Mucousy diahrrea




Hosts: rats, pigs, rhesus monkeys


Life-cycle: adults in cecum of ascending colon


Symptoms:


-one person got it and died of severe diarrhea


-flukes had bread and migrates all throughout his GI tract

Holostome characteristics

-sporocysts produce true daughter sporocysts (not redia). Unlike redia, these are single use, and are destroyed once they release cercaria.


-forked tail that hangs at water surface


-both first and second intermediates are (specific) snails


-Can infect trematode parasite in non-ideal host, killing the parasite


-tetracotyle metacercaria = flexible, no cyst


--allows it to bend and tear up parasite host using suckers

Cotylurus spp.

A holostome (the duck fluke)


-muscular pharynx around esophagus that grinds up food-


Host: ducks


-CDC introduces these ducks to lakes infected with other trematodes and it kills them



Alaria canis

A holostome


TL;DR: Dog small intestine holostome. Paratenic = tadpole then snake, mesocercaria in paratenic. Extra-intestinal migration in dog. Puppy thru mammary gland.



Hosts: various canadiae

Life-cycle:


-adults in small intestine


-eggs defecated out


-miracidium penetrates specific snail


-normal digenea lifecycle (except daughter sporocytes, not redia)


-cercaria with forked tail and no eyespot


-penetrates tadpole


mesocercaria: flexible metacercaria that doesn't encyst but migrates through body


-snake eats tadpole


-dog eats snake, mesocercaria comes out in intestine


-extra-intestinal migration


-matures in small intestine


-can get to nursing pup thru mammary gland


Symptoms: severe enteritis - often lethal


Zoogeography: Northern America

schistosome characteristics

-Most human infections of all trematodes


-daughter sporocytes rather than redia


-live in blood stream


-separate males and females


-->males wrap around females and carry through body


-Death is common


-Forked tail WITH eyespot

Schistosoma mansoni

A Schistosome

TL;DR: The human small intestine schistosome. Eggs flexible and porous->can move and secrete digestive enzymes. Break out of villi. Extreme blood loss. Symptoms gradual. Lateral spine. Weird symptoms from eggs being sucked back into blood.




Host: humans


Life-cycle:


-Adults in blood stream


-Male carries female to basal vessels of villus


-female extends into villus, excretes ~10 eggs


-->eggs porous & flexible


-->Miracidium secrete digestive enzymes through pores and can move due to flexibility


-Enzyme break down blood vascular in villus


-Eggs use lateral spine like rudder to move to top of villus


-breaks out, destroying villus, defecated out


-->(male carries female down and repeats next day)


-eggs hatch in water, miracidium -> snail


-unusual cercaria: forked tail WITH eyespot


-follows light to surface and hangs there


-detects disturbance made by human, penetrates skin


-tail drops off


-blood->lymph->lungs->heart->liver


-males wait for female in liver, embrace them


-small intestine




-sometimes eggs don't make it out of villus and sucked back into blood


-->liver, lungs,spleen, myocardium, spinal cord


PPP: egg depositing after 5-7, symptoms gradual


Symptoms: (increase with time)


-enormous blood loss => anemia


-classic mucousy/boody stool


-diarrhea


-weird symptoms in other organs due to eggs that got sucked back into blood


Zoogeography: egypt, porto rico, brazil, snails in Louisiana are susceptible.


Diagnosis: eggs with lateral spine in feces


-CDC trying to use duck fluke to eliminate

Schistosoma haematobium

A schistosoma


TL;DR: Human bladder schistosome, causes red urine. Terminal spine.




-S. mansoni-like


-Spine on terminus of egg, not lateral


Life-cycle: Males carry females to urinary bladder, not intestine


Symptoms: bloody red urine


Zoogeography: middle east (red sea and nile especially)


Diagnosis: eggs with terminal spine in urine



Schistosoma japonica

A Schistosoma


TL;DR: Asian human ileocecal schistosome that causes bad digestion -> emaciation, paleness, hardening tissue.




-S. mansoni-like


Host: humans


Life-cycle:


-ileocecal area rather than just small intestine


PPP: ~6 weeks


PP: up to 47 yrs


Symptoms:


-hard tissues


-weakness


-pale skin


-poor digestion => emaciation


Zoogeography: Asia

Schistosomatium douthitti

A schistosome


TL;DR: Rodent schistosome that causes cutaneous larval migrans called 'swimmers itch'.




Host: rodents and birds


Life-cycle:


-cant develop to maturity in humans


-free living aggressive cercaria still penetrate our skin


Symptoms:


-cutaneous larvale migrans calles "swimmer's itch"


Zoogeography:


-water puddles on oil fields

Platyhelminthes characteristics

-unsegmented


-flat


-cephalized


-Flame cells - excretion/osmoregulation


-Egg-shell system


-->egg released from ovary -> oviduct


-->vitellin cells in ovaduct coat egg in salt-like polyphenol crystals


-->egg moves to chamber connected to Mehlis gland, which secreted polyoxidase => essentially melts polyphenol crystals into shell



Which two parasites are used for biological control?

E. revolutum and cotylurus.




E. revolutum is used more often.

Smallest trematodes

heterophytes (which are Chlonorchis-like)

Watsonius watsoni

Amphistome




One guy got it and died of diarrhea