Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
8 Cards in this Set
- Front
- Back
|
Drug: Acyclovir
What is the mechanism of action? |
PURINE ANALOG (Guanasine analog) Inhibition of viral DNA synthesis (DNA polymerase inhibition) = monophosphorylated by VZV thymidine kinase and not phosphorylated in uninfected cells --> few adverse effects.
|
|
|
Drug: Amantadine
What is the mechanism of action? |
Inhibition of viral entry or uncoating
|
|
|
Drug: Cidofovir
What is the mechanism of action? |
Viral DNA polymerase inhibitor Inhibition of viral DNA synthesis (DNA polymerase inhibition) = inhibits DNA polymerase, does not require phosphorylation by viral kinase.
|
|
|
Drug: Oseltamavir
What is the mechanism of action? |
Neuraminidase inhibitor:
Inhibition of release of influenza virus from infected cell |
|
|
Drug: Ribavirin
What is the mechanism of action? |
Guanine nucleotide synthesis Inhibition of viral nucleic acid synthesis = inhibits synthesis of guanine nucleotides by competitively inhibiting inosine monophosphate dehydrogenase.
|
|
|
Drug: Rimantadine
What is the mechanism of action? |
Inhibition of viral entry or uncoating |
|
|
Drug: Valacyclovir
What is the mechanism of action? |
Pro-drug for acyclovir |
|
|
Drug: Zanamivir
What is the mechanism of action? |
Neuraminidase inhibitor:
Inhibition of release of influenza virus from infected cell |
