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19 Cards in this Set
- Front
- Back
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exotoxins that disrupt host cells
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cytotoxins
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an example of a pore forming cytotoxin
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Clostridium perfringens
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causative agent of gas gangrene
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C. perfringens
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what kind of toxin is the cholera toxin
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ADP ribosylating toxin
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rice water stools are associated with what toxin
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cholera toxin
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causative agent of whooping cough
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Bordetella pertussis
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what kind of toxin is pertussis toxin
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ADP ribosylating toxin
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morphology resembles chinese letters
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Corynebacterium
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what toxins ADP ribosylates host elongation factor (EF2) inhibiting protein synthesis and resulting in cell death
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diphtheria toxin
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what toxin cleaves synaptobrevins involved in the release of neurotransmitter
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botulinum toxin
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what is the net effect of botulinum toxin
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inhibits release of acetylcholine causing flaccid paralysis
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what toxin targets synaptobrevins in the CNS (not peripheral neurons)
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tetanus toxin
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what toxins blocks the release of GABA and glycine resulting in spastic paralysis
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tetanus toxin
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tetanus causes spastic paralysis whereas botulinum causes
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flaccid paralysis
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what type of toxin results in stimulation of numerous T cells causing a massive inflammatory reaction leading to shock
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superantigens
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what three major cytokines play an important role in eliciting fever
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TNF
IL-1 IL-6 |
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GI illness that is caused by ingestion of a preformed toxin
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food poisoning
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GI illness caused by ingestion of bacteria
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food infection
toxin is produced following infection |
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Salmonella is an example of what kind of GI illness
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a food infection
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