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36 Cards in this Set
- Front
- Back
Name 3 factors contributing to GERD.
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1) drinking alcohol
2) smoking cigarettes 3) consuming various foods (high fat content, caffiene, citrus, and spices) |
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Therapy for GERD
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Using a combination of medications
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Antacid agents used to treat GERD (2):
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1) aluminum hydroxide-magnesium carbonate (Gaviscon ES)
2) magnesium hydroxide (Milk of Magnesia) |
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H2 antagonists to treat GERD (2):
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1) cimetidine (Tagamet)
2) ranitidine (Zantac) |
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Name 3 agents used to treat GERD.
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1) antacids
2) H2 antagonists 3) Proton pump inhibitors |
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Name 4 therapeutic uses of ranitidine (Zantac).
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1) active duodenal ulcers
2) benign gastric ulcers 3) long-term prevention of duodenal ulcers 4) GERD |
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What are 2 proton pump inhibitor agents for GERD (2)?
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1) Iansoprazole (Prevacid)
2) omeprazole (Prilosec) |
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Which agents for GERD are indicated for short-term treatment?
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1) Iansoprazole
2) omeprazole |
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What is a primary side effect of omeprazole?
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diarrhea
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Which drug is indicated for short-term therapy of ulcers and esophagitis?
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Iansoprazole
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Name 3 common types of ulcers.
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1) Gastic
2) Duodenal 3) Stress |
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What is the prevalence of gastric ulcers?
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1) occur more in men than women
2) smokers 3) populations in Western Hemispheres |
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What is a duodenal ulcer?
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a peptic lesion in the duodenum
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Duodenal ulcers are more difficult to treat than gastric ulcers. Why?
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It is difficult to get medication to the duodenum.
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What causes stress ulcers?
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Severe physiological stress
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Patients in the ICU usually get stress ulcers. What do they receive to relieve these ulcers?
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prophylactic therapy of H2 antagonists
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Which 4 drugs may cause ulcers?
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1) alcohol
2) aspirin 3) anti-inflammatory drugs 4) corticosteroids |
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What is an adverse effect of alcohol?
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irritating to the GI tract
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What is an adverse effect of aspirin?
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irritating to the GI tract
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What is an adverse effect of anti-inflammatory drugs?
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reduce production of mucus
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What is an adverse effect of corticosteroids?
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reduce the mucosal barrier
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What is the cause of most peptic ulcer?
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H. pylori
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How does H.pylori cause peptic ulcers?
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it secretes enzymes that neutralize stomach acid.
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What is the mainstay therapy for pharmacologic treatment of H. pylori?
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Antibiotics
-mixed w/antacid or proton pump inhibitor |
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Name 2 antibiotic agents for H. pylori.
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1) amoxicillin
2) tetracycline |
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NON-OPIOIDS CARD SET
NAME 3 NON-OPIODS. |
1) SALICYLATES
2) NSAIDS 3) ADJUNCTS |
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NON-OPIOID CARD SET
GIVE AN EXAMPLE OF A SALICYLATE. |
ASPIRIN (BAYER)
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NON-OPIOID CARD SET
WHAT DOES NSAID STAND FOR? |
NON-STEROIDAL ANTI-INFLAMMATORY DRUGS
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NON-OPIOID CARD SET
GIVE 4 EXAMPLES OF NSAIDS. |
1) IBUPROFEN (MOTRIN, ADVIL)
2) NAPROXEN (NAPROSYN) 3) NAPROXEN SODIUM (ALEVE) 4) KETORALAC (TORADOL) |
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NON-OPIOID CARD SET
NSAIDS COMPETE WITH _____ FOR _________________. |
-ASPIRIN
-PROTEIN BINDING SITES |
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NON-OPIOID CARD SET
NAME 3 THINGS THAT NSAIDS HELP TO DECREASE. |
1) FEVER
2) INFLAMMATION 3) PAIN |
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NON-OPIOID CARD SET
WHICH NSAID DOES NOT HELP DECREASE INFLAMMATION? |
ACETAMINOPHEN
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NON-OPIOD CARD SET
WHICH ENZYME IS RESPONSIBLE FOR THE SYNTHESIS OF PROSTAGLANDINS AND THROMBOXANE A? |
CYCLOOXYGENASE (COX)
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NON-OPIOD CARD SET
WHAT NSAID INHIBITS THE SYNTHESIS OF CYCLOOXYGENASE? |
ASPIRIN
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NON-OPIOID CARD SET
WHAT ARE THE NEGATIVE EFFECTS OF ASPIRIN? |
1) GI ULCERATION
2) INCREASE BLEEDING 3) DECREASE RENAL ELIMINATION 4) DECREASE UTERINE CONTRACTION DURING LABOR |
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NON-OPIOID CARD SET
HOW IS ACETAMINOPHEN (TYLENOL) DIFFERENT FROM ASPIRIN? |
ACETAMINOPHEN ONLY INHIBITS SYNTHESIS OF CNS PROSTAGLANDINS.
IT DOES NOT HAVE PERIPHERAL SIDE EFFECTS LIKE ASPIRIN. |