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61 Cards in this Set

  • Front
  • Back

the integumentary system

the largest system in your body


17-20 sq. feet if a person was skinned


makes up about 16%of your body weight


has the most diseases associated with this system vs. any other system in the body


about 5% of your blood is ass. with this system

dermatology

the study of skin

functions of the skin

protection


water barrier: prevents desiccation and provides waterproofing


protects from UV light


protects you from microbes, environmental things, and poisons


first line of defense against disease


regulates body heat


tactile receptors


separates you from the outside world


allows for movement


important in electrolyte balance


helps make vitamin D through vitamin D synthesis


can be important in absorption such as trans-dermal patches




epidermis

the outside of the skin

keratinocyte

most numerous cells of the skin. hardened by keratin. important in waterproofing and immunity

melanocytes

very distinct cells located at the base of the epidermis. associated with the brown pigment melanin. melanin is responsible for protection against UV light.

melanin

responsible for the color of skin.




in Caucasians: melanin would be located in stratum basale in a lower place




in brown skin; melanin would be located higher up in the stratum basale



albinism

have the same number of melanocytes but they are not working properly; such as problems in tyrosine.

vitiligo

have patchy white or colorless spots on the skin. results of melanin mal-metabolic functions



tyrosine

is important in the formation of melanin

langerhans cells

rise from the bone marrow and migrate to the epidermis. these cells are important in immunity. work in conjunction with a type of lymphocyte called a killer T.

grinstein cells

these cells help in protection of UV light. They help with suppressor cells made up of stratified squamous tissue.

Thick skin

type of skin that has 5 layers


ex: soles of the feet,palms of your hands


more involvement of the dermis



thin skin

type of skin made up of 4 layers


stratum corneum

outermost layer of skin


located in thick and thin skin


flat, dead, filled with keratin


good for waterproofing


you shed this layer of the skin constantly


associated with perspiration

insensible perspiration

...

sensible perspiration

...

stratum lucidum

found in thick skin only


ex: the palms of your hand and soles of your feet


contains droplets of eliden, which is important informing keratin



stratum granulosum

flat in cells about 5 layers thick


contains the chemical keratohylin


the nucleus is in the process of dying


keratinzation is still occurring


tonodilaments: help in slowing down water loss

stratum spinosum

contains spine-like stuctures called prickle cells


langerhans cells


demosomes


shape varies


these cells are alive



stratum basale or germinativum

the innermost layer of the skin


cubodial or columnar shaped


undergo cell division


25%of the cells are melanocytes


associated with epidermal ridges


mekel cells: sensitive to touch



pallor

a type of paleness of the skin that may be due to several things

bronze

a bronzing of the skin, almost metallic; due to addison's disease

jaundice

a yellowing of the skin or sometimes the whites of the eyes. can be cause by alcoholism or a bacterial infection such as herpes.

hematoma

bruising of the skin

erythema

a redness of the skin such as being due to embarrassment, fever, hypertension

dermis

very thick in some areas such as the feet and the palms of the hands


contains numerous blood vessels


associated with hair follicles


have a lot of nerve cells

papillary area

the outer region of the dermis, such as the fingerprints.


you see numerous ridges called dermal papillae

reticular area

under the papillary area


the innermost portion of the dermis


it's tougher, more dense, and has a lot of collagen


a lot of fat and blood vessels associated with this area


contains hair follicles and macrophages


associated with wrinkles


allows for swelling



striae

stretch marks

hypo-dermis

attached to the dermis on its upper end and a membrane on its lower en


made up of connective tissue and fat

hair

the most obvious accesory organ in mammals


found all over the body


it's ornamental


it can be used for heat regulation


can be used for touch


provides protection


reduces friction

lanugo hair

fine hair that we usually loose after birth. hormones contribute to the loss of this hair

vellus hair

fine hair


you may see this on the legs and arms of little kids



terminal hair

the hair on you hair or eyebrows

hypertichosis

wolf man; excessive hair

atrichosis

lack of hair

hirsutism

excessive hair on females such as the bearded lady, cause by a tumor on the adrenal gland

3 distinct regions of hair

1. cuticle: outermost region of the hair. highly keratinized.


2. cortex: the middle part of the hair. containd the pigments of hair.


3. Medulla: the innermost region of the hair. has a lot of air spaces.

sebum

produced by sebaceous glands; keep hair healthy and shiny

alopecia

balding (more common in males)



nails

highly keratinized regions in the terminal portions of toes and hands


help to protect the tops of our hands

3 parts of the nail

1. nail body: most of your nail


2. the free edge: the end of your nail


3. lunular: the cuticle, the outermost region of the nail

sudoriferous glands

sweat glands


important in thermo regulation

cystic fibrosis

sweat excessively

mammary glands

a type of sweat gland that is designed to produce milk


this gland destroys itself in the act of making milk


the number of these glands is set genetically (ex:humans have 2)

ceruminous glands

wax glands of the ear


trap dirt and other foreign objects

lacrimal glands

tear glands

meiobian glands

modified sebaceous glands; they secrete oil onto the eyeball

epidermal healing

what happens when your cat nicks you


cell division increases and heals in a couple of days

dermal healing

takes longer to heal


causes scarring

sepsis

A life-threatening complication of an infection.

the rule of nine

1st degree burns

superficial burn


just makes your skin red and swelling


is painful


usually heals in 2-3 days without special attention


may peel

2nd degree burns

partial thickness burn


blistered pink region around the burn


red color and swelling


effects the epidermis and the upper dermis


painful


heals well in a couple of weeks


usually hair and glands with repair themselves

3rd degree burn

full thickness


tissue damage is extensive


Involves massive necrosis


Can vary in color (white, black red)


You can smell the tissues burning


They can be dried out or they can be wetEschar: the crusty appearance around 3rd degreeburns


Involve intensive medical care.


Make require skin grafts

neoplasm

an abnormal growth of cells; mostly benign and not cancerous

basal cell carcinoma

the most common type of skin cancer


due to UV exposure


Have lesions in the skin exposed portion of the body such asthe face


Startsoff shiny then it starts becoming dome shaped and in the middle of the domethere will be an ulcer.


Thelayer of the skin effected the most with this type of skin cancer is the Basalelayer.


Can be cut out


Itwon’t spread (metastasis) for the most part.

squamous cell carcinoma

Develops in the stratum spinosum and the keratinocytes

Scaly and red lesions


Appear on the scalp, back of hand, or ear.Requires a lot of incisions or chemotherapy


for the most part recovery is okay.

ABCDE rule of skin moles

A: asymmetry- A benign mole has smooth, even borders, unlike melanomas.


B: border- A benign mole has smooth, even borders, unlike melanomas.


C: color-Most benign moles are all one color


D: diameter-Benign moles usually have a smaller diameter than malignant ones.


E: evolving-Common, benign moles look the same over time.

aging and integument

The skin thinsBruising will increase

The immune response to the skin decreases Melanocyte production fails


The hair will lose pigment or fall out


The skin will take longer to heal


The dermis will thin andlose its elastic ability The circulation of blooddecreases within the skin


Thermos regulatory problems.