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33 Cards in this Set

  • Front
  • Back

Synaptic communication

Chemical - Neurotransmitter


Pre and postsynaptic specializations


Electrical - Gap junctions





Axiomatic synapse

Axon to cell body

Axodendritic synapse

Axon to dendrite or dendrite spine

Axoaxonic synapse

axon to axon

Excitatory neuron

increase probability that the motor neuron will fire

Inhibitory neuron

decrease probability that the motor neuron wildfire an action potential

1000- 10000

connections to a motor neuron

Steps in synaptic communication

action potential comes to invade a nerve tunnel opening calcium gates

Neurotransmitter examples

Excitatory- acetylcholine, glutamine, serotonin


Inhibitory- GABA, glycine


Small peptides- substance P, VIP, CCK


Gaseous transmitters- nitric oxide

Thickenings on slides

define synapses for transmission for dendrites where vesicles are not present.




Synaptic vesicles are axon to axon

striated outer lining on slides

myelin sheath



Central nervous system - Cerebral cortex

6 layers




Distinguish between glial cells, neurons, blood vessels.

CNS- Cerebellar cortex

Basket cells


Dendrite of purkinje cell


purkinje cell body


Granule cells ( small neurons)


axons

Granule cells

small neurons

Supporting cells CNS

Neuroglia: oligodendrocytes, astrocytes, microglia ( bone marrow ), enpendyml cells

Supporting cells PNS

Schwann cells, satellite cells

Enpendyml cell

line the brain ventricle


junctional complexes that restrict movement of CSF between cells


motile cilia that set up current in the spinal fluid that fills the ventricles



Astrocyte

neurotransmitter uptake


fibrous ( white matter ) and protoplasmic ( grey matter )


Astrocytic feet on capillaries influence blood- brain barrier


Physically an metabolically support " neuropil"

microglial

macrophages of the nervous system


Phagocytose for a living


migrate for immune surveillance





H&E stain section neuroglial

small, dense nucleus, not much cytoplasm

protoplasmic astrocyte

found in grey matter with all of the neurons

white matter

lots of myelin where we find fibrous astrocytes

microglia

smaller than astrocyte. small branches

oligodendrocytes

produce and maintain myelin in CNS


single cell can myelinated multiple axons


myelinated with processes



schwann cells

myelinated one segment per cell. Go to the axon and rotate around and lay down the myelin sheath with its cell body

spinal cord

covered by the meninges- dura matter, arachnoid, pia matter


posterior horn- receives info


anterior horn - send info out , motor neurons ( biggest cell bodies)


posterior root and anterior root combine to go out to foot.


Dorsal root ganglian


"butterfly " grey matter surrounding it is white matter



PNS terms and concepts:

nerve( group of axons in the PNS ) vs. neuron(complete cell of the nervous system ) vs. tract.( group of axons within CNS nerve going into brain)


Neuron cell body locations ( located in the spinal cord and in the dorsal root ganglia )


motor neuron cell bodies, axons


sensory neuron cell bodies

epineurium outer layer , perineurium layer in between , endoneurium individual outer layer

covering sheaths of nerves

Myelinated vs. Unmyelinated

Schwann cells wraps around a neurolemmocyte.


and conducts rapidly




unmyelinated responds more slowly

PNS

ganglion

CNS

nucleus

Dorsal root ganglia

along side the spinal cord


contain primary sensory neurons


satellite cells

gamma motor neurons

send signals to the spindles to tell them to contract a little to stay in the range of sensitivity