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65 Cards in this Set
- Front
- Back
Anabolism
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Build up; synthesis of proteins; syn. Of triglycerides from fatty acids and glycerol; syn of glycogen from glucose
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Catabolism
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Breaking down; oxidation of glucose to CO2+H2O+energy in the form of ATP
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Deamination
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Loss of amino group
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Decarboxylation
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Loss of carboxyl group
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Dehydrogenation
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Loss of hydrogens; H picked up by NAD
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Metabolism
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All chemical reactions that occur in our body.
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Acetyl Co-A
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2 carbon acetyl group(NADH+H+CO2) combined with coenzyme-A; the "ticket" to the kreb's cycle (prepares pyruvic acid for the krebs cycle)
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Acids in the Kreb cycle
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Oxaloacetic(6)
Citric(6) Isocitric(6) A-ketoglutaric(5) Succinyl CoA(4) Succinic(4) Fumaric(4) Malic(4) Oxaloacetic(4) |
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Glycogenesis
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Conversion of glucose to glycogen stimulated by INSULIN. Glycogen stored in liver and muscle
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Glycogenolysis
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Conversion of glycogen back to glucose. Glycogen converted completely to glucose only in the liver bc this is the only place where enzyme phosphatase is located. Under control of EPINEPHRINE and GLUCAGON.
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Gluconeogenesis
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Glucose from a new source such as the conversion of amino acids, fatty acids, and glycerol to glucose. Process stimulated by CORTISOL (adrenal gland) and GLUCAGON (pancreas). Occurs in the liver when glucose levels are low.
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Lipogenesis
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Conversion of glucose or amino acids to fats. Requires precursor molecules, intermediates, and coenzymes and INSULIN.
Lipid anabolism |
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Beta oxidation
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removal of carbons two at a time. Two carbon fragments may be conv to acetyl CoA which can enter the krebs cycle or can be conv to glucose. Most are conv to ketone bodies.
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Ketosis (aka acidosis)
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Excess of ketone bodies. Happens in diabetes mellitus where glucose is unavailable and fats are burned in excess.
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Ketogenesis
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2 carbon fragments are converted to ketone bodies
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The principal classes of nutrients are:
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carbohydrates, lipids, proteins, minerals, vitamins, and water
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in discussing metabolism we emphasized that the breaking down process is known as?
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catabolism
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what best describes biological oxidation?
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loss of Hydrogen
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reduced form of NAD?
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NAD
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the enzyme that was emphasized as being the primer for glucose was?
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hexokinase (in liver)
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what is the primary oxidizing agent in biological systems?
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NAD
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gycolysis is?
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the breakdown of glucoase to two pyruvic acid molecules
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anaerobic occurs in the ______ of O2 and produces ______ energy (ATP) for the cell than aerobic respiration.
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absence, less
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a molecule that moves electrons from the citric acid cycle to the electron transport chain is:
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pyruvic acid
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in the absence of O2 pyruvic acid is converted to ____, and most of this is dealt with via the _______ cycle.
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lactic acid; cori
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T/F the "net" gain of ATP in glycolysis is 4.
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false
net gain is 2 |
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which one was emphasized as being a 5 carbon compound?
fumaric/citric/alpha ketoglutaric/malic/oxaloacetic |
alpha ketoglutaric
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which one was emphasized as being the first to lose a carbon?
isocitric/succinyl CoA/citric/fumaric/acetyl CoA |
isocitric
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______ & _______ are the compounds that enter the electron transport chain.
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FADH2 & NADH2
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the iron containing compounds in the ETC that accept electrons are known as?
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cytochrones
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the TERM for the loss of CO2 by pyruvic acid is ?
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decarboxylation
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once O2 enters the metabolic process that we discussed in class, how many times did we see CO2 removed from a molecule that was involved in the process?
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three
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FAD is involoved in the Kreb's cycle between which two "players"?
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succinic and fumaric
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both the Kreb's cycle and the elctron transport reactions occur in which organelle of the cell?
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mitochondria
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oxygen is needed in:
glycolysis/krebs cycle/ETC |
none of these
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the four products that are eliminated from the krebs cycle are
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NADH2, FADH2, CO2, H+
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"2"carbon compound associated with the Kreb's cycle
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the acetyl group
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there is one molecule of ATP generated for each cycle of the Kreb's cycle. This occurs between ____ & ____ molecules?
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succinyl CoA and succinic
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list acids in the Krebs cycle in the proper squence
(partial list) |
citric, a-ketoglutaric, succinyl CoA, succinic
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when oxygen is consumed in the ETC there is resultant formation of?
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CO2
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glycogenesis occurs under the influence of which one of the following hormones?
glucagon/cortisol/norepinephrine/insulin |
insulin
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when do you suppose would be the MOST LIKELY time for glycolysis to occur?
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between meals
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lipids that are not used by the body are usually...
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stores in adipose tissue
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which hormones are involved in catabolizing fats?
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HGH, glucagon, epinephrine
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in lipogenolysis we saw that glycerol is first converted to
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glyceraldehyde-3-phosphate
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the TERM for the loss of CO2 by pyruvic acid is ?
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decarboxylation
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once O2 enters the metabolic process that we discussed in class, how many times did we see CO2 removed from a molecule that was involved in the process?
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three
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FAD is involoved in the Kreb's cycle between which two "players"?
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succinic and fumaric
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both the Kreb's cycle and the elctron transport reactions occur in which organelle of the cell?
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mitochondria
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oxygen is needed in:
glycolysis/krebs cycle/ETC |
none of these
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lipids are primarily stored as what?
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triglycerides
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beta oxidation is a term that has reference to the catabolism of?
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fatty acids
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T/F it was emphasized that the carbon fragments from beta oxidation can be converted to glucose
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false
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T/F glycogen can be converted to free glucose in the liver because the liver contains phosphates
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true
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it was emphsized that amino acid fragments must go through the process of glycolysis before they can enter the Kreb's cycle
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false
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NH3 is converted to urea via the ____ cycle, and the process occurs in the ___?
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ornathine; liver
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transamination and deamination are terms associated with ?
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protein metabolism
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amino acids...
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*are classified as essential/nonessential
*can be synthesized in a transamination reaction *can be used as a source of energy *can be converted to keto acids |
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Cellular respiration
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The oxidation of glucose to produce ATP. It involves four sets of reactions: glycolysis, the formation of acetyl CoA, the krebs cycle, and the electron transport chain
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Glycolysis
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The conversion of glucose to pyruvic acid. Occurs in the cytosol and is anaerobic
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Ketone bodies
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Ex of: Acetone and acetoacetic acid
Liver can't conv ketone bodies to intermediate products therefore they are dumped into the blood where they are carried to cells where they are conv to acetyl CoA |
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2 things that must happen to pyruvic acid before it can enter the krebs cycle
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Decarboxylation and dehydrogenation and the 2 carbon acetyl group must combine with coenzyme A to form acetyl CoA (ticket to Krebs)
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How many ATP generated with oxidation of one glucose molecule?
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38~ 2 glycolyisis
2 Krebs cycle 34 ETC |
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Intracellular fluid (ICF) makes up what % of total body water?
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62.5%
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Lymph
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Formed by filtration of the blood-same as tissue or interstitial fluid except when it enters the lymphatic vessels it is called lymph
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