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65 Cards in this Set

  • Front
  • Back
Anabolism
Build up; synthesis of proteins; syn. Of triglycerides from fatty acids and glycerol; syn of glycogen from glucose
Catabolism
Breaking down; oxidation of glucose to CO2+H2O+energy in the form of ATP
Deamination
Loss of amino group
Decarboxylation
Loss of carboxyl group
Dehydrogenation
Loss of hydrogens; H picked up by NAD
Metabolism
All chemical reactions that occur in our body.
Acetyl Co-A
2 carbon acetyl group(NADH+H+CO2) combined with coenzyme-A; the "ticket" to the kreb's cycle (prepares pyruvic acid for the krebs cycle)
Acids in the Kreb cycle
Oxaloacetic(6)
Citric(6)
Isocitric(6)
A-ketoglutaric(5)
Succinyl CoA(4)
Succinic(4)
Fumaric(4)
Malic(4)
Oxaloacetic(4)
Glycogenesis
Conversion of glucose to glycogen stimulated by INSULIN. Glycogen stored in liver and muscle
Glycogenolysis
Conversion of glycogen back to glucose. Glycogen converted completely to glucose only in the liver bc this is the only place where enzyme phosphatase is located. Under control of EPINEPHRINE and GLUCAGON.
Gluconeogenesis
Glucose from a new source such as the conversion of amino acids, fatty acids, and glycerol to glucose. Process stimulated by CORTISOL (adrenal gland) and GLUCAGON (pancreas). Occurs in the liver when glucose levels are low.
Lipogenesis
Conversion of glucose or amino acids to fats. Requires precursor molecules, intermediates, and coenzymes and INSULIN.

Lipid anabolism
Beta oxidation
removal of carbons two at a time. Two carbon fragments may be conv to acetyl CoA which can enter the krebs cycle or can be conv to glucose. Most are conv to ketone bodies.
Ketosis (aka acidosis)
Excess of ketone bodies. Happens in diabetes mellitus where glucose is unavailable and fats are burned in excess.
Ketogenesis
2 carbon fragments are converted to ketone bodies
The principal classes of nutrients are:
carbohydrates, lipids, proteins, minerals, vitamins, and water
in discussing metabolism we emphasized that the breaking down process is known as?
catabolism
what best describes biological oxidation?
loss of Hydrogen
reduced form of NAD?
NAD
the enzyme that was emphasized as being the primer for glucose was?
hexokinase (in liver)
what is the primary oxidizing agent in biological systems?
NAD
gycolysis is?
the breakdown of glucoase to two pyruvic acid molecules
anaerobic occurs in the ______ of O2 and produces ______ energy (ATP) for the cell than aerobic respiration.
absence, less
a molecule that moves electrons from the citric acid cycle to the electron transport chain is:
pyruvic acid
in the absence of O2 pyruvic acid is converted to ____, and most of this is dealt with via the _______ cycle.
lactic acid; cori
T/F the "net" gain of ATP in glycolysis is 4.
false
net gain is 2
which one was emphasized as being a 5 carbon compound?
fumaric/citric/alpha ketoglutaric/malic/oxaloacetic
alpha ketoglutaric
which one was emphasized as being the first to lose a carbon?
isocitric/succinyl CoA/citric/fumaric/acetyl CoA
isocitric
______ & _______ are the compounds that enter the electron transport chain.
FADH2 & NADH2
the iron containing compounds in the ETC that accept electrons are known as?
cytochrones
the TERM for the loss of CO2 by pyruvic acid is ?
decarboxylation
once O2 enters the metabolic process that we discussed in class, how many times did we see CO2 removed from a molecule that was involved in the process?
three
FAD is involoved in the Kreb's cycle between which two "players"?
succinic and fumaric
both the Kreb's cycle and the elctron transport reactions occur in which organelle of the cell?
mitochondria
oxygen is needed in:
glycolysis/krebs cycle/ETC
none of these
the four products that are eliminated from the krebs cycle are
NADH2, FADH2, CO2, H+
"2"carbon compound associated with the Kreb's cycle
the acetyl group
there is one molecule of ATP generated for each cycle of the Kreb's cycle. This occurs between ____ & ____ molecules?
succinyl CoA and succinic
list acids in the Krebs cycle in the proper squence

(partial list)
citric, a-ketoglutaric, succinyl CoA, succinic
when oxygen is consumed in the ETC there is resultant formation of?
CO2
glycogenesis occurs under the influence of which one of the following hormones?
glucagon/cortisol/norepinephrine/insulin
insulin
when do you suppose would be the MOST LIKELY time for glycolysis to occur?
between meals
lipids that are not used by the body are usually...
stores in adipose tissue
which hormones are involved in catabolizing fats?
HGH, glucagon, epinephrine
in lipogenolysis we saw that glycerol is first converted to
glyceraldehyde-3-phosphate
the TERM for the loss of CO2 by pyruvic acid is ?
decarboxylation
once O2 enters the metabolic process that we discussed in class, how many times did we see CO2 removed from a molecule that was involved in the process?
three
FAD is involoved in the Kreb's cycle between which two "players"?
succinic and fumaric
both the Kreb's cycle and the elctron transport reactions occur in which organelle of the cell?
mitochondria
oxygen is needed in:
glycolysis/krebs cycle/ETC
none of these
lipids are primarily stored as what?
triglycerides
beta oxidation is a term that has reference to the catabolism of?
fatty acids
T/F it was emphasized that the carbon fragments from beta oxidation can be converted to glucose
false
T/F glycogen can be converted to free glucose in the liver because the liver contains phosphates
true
it was emphsized that amino acid fragments must go through the process of glycolysis before they can enter the Kreb's cycle
false
NH3 is converted to urea via the ____ cycle, and the process occurs in the ___?
ornathine; liver
transamination and deamination are terms associated with ?
protein metabolism
amino acids...
*are classified as essential/nonessential
*can be synthesized in a transamination reaction
*can be used as a source of energy
*can be converted to keto acids
Cellular respiration
The oxidation of glucose to produce ATP. It involves four sets of reactions: glycolysis, the formation of acetyl CoA, the krebs cycle, and the electron transport chain
Glycolysis
The conversion of glucose to pyruvic acid. Occurs in the cytosol and is anaerobic
Ketone bodies
Ex of: Acetone and acetoacetic acid
Liver can't conv ketone bodies to intermediate products therefore they are dumped into the blood where they are carried to cells where they are conv to acetyl CoA
2 things that must happen to pyruvic acid before it can enter the krebs cycle
Decarboxylation and dehydrogenation and the 2 carbon acetyl group must combine with coenzyme A to form acetyl CoA (ticket to Krebs)
How many ATP generated with oxidation of one glucose molecule?
38~ 2 glycolyisis
2 Krebs cycle
34 ETC
Intracellular fluid (ICF) makes up what % of total body water?
62.5%
Lymph
Formed by filtration of the blood-same as tissue or interstitial fluid except when it enters the lymphatic vessels it is called lymph