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161 Cards in this Set

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Biology

The study of living organisms and their environments

Atom

Smallest unit of an element of matter composed of electrons, protons, and neutrons

Structural unit of all matter

Molecule

Union of 2 or more atoms of the same or different elements

Tissue

A group of similar cells that perform a particular function

A group of cells with a common structure and function

Humans are

Multicellular

All living things

Take energy via environment; need energy to survive

E.G., Humans - eat food

Organ

Composed of tissues functioning together for a specific task

Organ system

Several types of organs that work together to accomplish a common purpose

The brain works with the spinal cord to send commands to body parts by way of nerves

Organism

A collection of of organ systems


An individual


Complex individuals contain organ systems

E.G., Trees and humans; all living things

Species

A group of Interbreeding organisms

Population

A group of species/ organisms in a particular area

E.g., a tropical grassland - zebras, acacia trees, and humans

Community

Interacting populations in a particular area

Ecosystem

A community plus the physical environment

Biosphere

Made up by the Earth's ecosystems


Regions of the Earth's crust, waters, and atmosphere inhabited by living things

Levels of biological organization

Atom


Molecule


Cell


Tissue


Organ


Organ system


Organism


Population


Community


Ecosystem


Atmosphere

Matter

Anything that occupies space

Cell

The structural and functional unit of all living things

Can survive on its own

What characteristics are shared by living organisms?

Organized from the atom to the biosphere


Use materials and energy from the environment


Maintain a relatively constant internal environment (homeostasis)


Respond to internal and external stimuli


Reproduce and grow


Have an evolutionary history through which organisms change over time

How do we classify humans?

Domain: Eukarya


Kingdom: Animalia


Phylum: Chordata


Class: Mammalia


Order: Primates


Family: Hominidae


Genus: Homo


Species: Sapiens

How do we classify house cats?

Domain: Eukarya


Kingdom: Animalia


Phylum: Chordata


Class: Mammalia


Order: Carnivora


Family: Felidae


Genus: Felis


Species: Domesticus

What distinguishes humans?

Cultural heritage or patterns of our behavior passed from one generation to the next


Highly developed brains


Completely upright stance


Creative language skills


Varied tool use


Modification of our environment for our own purpose which may threaten the biosphere

What do we know about science?

Science is a way of knowing about the natural world


Science and scientists should be objective


Scientific conclusions may change or be modified as our understanding and technology increase


Science is studied using the scientific method

Cell Theory

All organisms are composed of cells, and new cells only come from pre-existing cells

Homestasis

The internal environment of an organism stays relatively constant

Genes

Organisms contain coded information that dictates their form, function, and behavior

Ecosystem

Populations of organisms interact with each other and the physical environment

Evolution

All organisms have a common ancestor, but each is adapted to a particular way of life

The steps of the scientific method

Observation


Hypothesis


Experiment/ Observations


Conclusion - goes back to Hypothesis


Scientific Theory

How the cause of ulcers was discovered

Observations: Many patients had a particular bacterium near their ulcers


Hypothesis: Helicobacter pylori is the cause of gastritis and ulcers


Experiment/observations: 1) H pylori was isolated and grown from ulcer patients


2) Humans swallowing a H pylori solution developed inflammation in their stomachs


Conclusion: H pylori was the cause of most ulcers and can be cured by antibiotics

Experimental Variable

The variable that is purposely changed or manipulated


All other variables need to remain constant

Test Group

A group of subjects that are exposed to the experimental variable

Control Group

A group for comparison that is not exposed to the experimental variable

Double Blind Study

The doctor doesn't know if the patient is in the control or test group


The patient doesn't know if they are in the control or test group

Reading about scientific information

Scientific journals are considered the best source of information but can be difficult for the lay person to understand


Often the lay person reads secondary sources and must be wary of information taken out of context


Be careful of information on the internet by using reliable sources such as URLs with .edu, .gov, and .org

What should you look for when you read about science

Beware of anecdotal data


Understand methodology and results


Does the data justify the conclusions inferred by the scientists?


Be able to read a graph


Have some understanding of statistics

Does science have social responsibilities?

Science is a way of acquiring knowledge about the natural world through a systematic process separating it from ethics, religion, and aesthetics

Technology

The application of scientific knowledge to human interests

Biotechnology

Genetically modified bacteria and genetically modified crops

Gene technology

Cloning of humans or gene therapy to modify inheritance

Embryonic stem cells

Use of stem cells from embryos

Everyone is responsible

The Western World believes that science and technology improve our lives


All citizens should assume responsibility


Everyone needs to be involved in making value judgements about the proper use of technology

Tight junction

Neighboring cells are connected by a zipper-like barrier

Watertight seal

Gap junction

Communication channels between cells

Tunnels between cells

Adhesion junctions

Cytoskeletons of 2 adjacent cells are interconnected

Water and small molecules come through 'spot welds'

Cell theory

A cell is the basic unit of life


All living things are made up of cells


New cells arise from pre-existing cells

Flies and meat experiment

Endoplasmic reticulum

Often produces transport vesicles that are then sent to the plasma membrane or Golgi apparatus

Proteins and lipids are manufactured here

Surface-area-to-volume ratio

Small cells have larger surface area compared to the volume


An increase in surface area allows for more nutrients to pass into the cell and wastes to exit the cell more efficiently


There is a limit to how large a cell can be, and be an efficient and metabolically active cell

Compound light microscope

Lower magnification


Uses ligth beans to view images


Can view live specimens

Transmission electron microscope

2-D image


Uses electrons to view internal structure


High magnification, no live specimens

Transmission electron microscope

2-D image


Uses electrons to view internal structure


High magnification, no live specimens

Scanning electron microscope

3-D image


Uses electrons to view surface structures


High magnification, no live specimens

Cells vary in structure and function

Cells vary in structure and function

Cells vary in structure and function

Blood cells viewed with different microscopes

Carrier proteins

Are specific; aid in both facilitated transport and active transport

What are the 2 major types of cells in all living organisms?

Prokaryotic and eukaryotic cells

What are the 2 major types of cells in all living organisms?

Prokaryotic and eukaryotic cells

Prokaryotic cells

Thought to be the first cells to evolve


Lack a nucleus - but have DNA


Represented by bacteria and archaea


Unicellular; single/simple lifeforms i.e., amoeba, bacteria

PRO - NO

Eukaryotic cells

Have a nucleus that houses DNA


Many membrane-bound organelles


More organized than prokaryotes


Multicellular i.e., animals, humans, plants

EU - DO

What do eukaryotic cells look like?

What are some characteristics of the plasma membrane?

Phospholipid bilayer


Embedded with proteins that move in space


Contains cholesterol for support


Selectively permeable

What does selectively permeable mean?

Allows some things in while keeping other substances out

How do things move across the plasma membrane?

Diffusion


Osmosis


Facilitated transport


Active transport


Endocytosis and exocytosis

Diffusion

The random movement of molecules from a higher concentration to a lower concentration

Osmosis

The diffusion of water molecules

Only small molecules and water

Isotonic solutions

Have equal amounts of solute inside and outside the cell and thus do not affect the cell

Cells can only survive in isotonic solutions

Tonicity

Concentration of solution

Hypotonic solution

Has less solute than the inside of the cell and lead to lysis (bursting)

Lower molecules in solution, will enter cells for equilibrium; cause cells to burst, i.e., Haemophilia

Hypertonic solutions

Have more solute than the inside of the cell and lead to cremation (shriveling)


Water leaves cell and causes shriveling i.e., Anaemia

Solution

Solvent + solute

Cell membrane = strainer

Facilitated transport

The transport of molecules across the plasma membrane from higher concentration to lower concentration via a protein carrier

Active transport

The movement of molecules from a lower to higher concentration using ATP as energy; it requires a protein carrier

Active transport

The movement of molecules from a lower to higher concentration using ATP as energy; it requires a protein carrier

Endocytosis

Transports molecules or cells into the cell via invagination of the plasma membrane to form a vesicle

Transports inside cell

Exocytosis

Transports molecules outside the cell via the fusion of a vesicle with the plasma membrane

Transports outside cell

Exocytosis

Transports molecules outside the cell via the fusion of a vesicle with the plasma membrane

Transports outside cell

What structures are involved in protein production?

Nucleus


Ribosomes


Endomembrane system

Lysosome

Digests macromolecules and cell parts

Golgi apparatus

Processes and modifies cell parts

Proteins and lipids are modified here

Vesicle

Storage of cellular materials

Ribosomes

Protein synthesis

Ribosomes

Protein synthesis

Join with amino acids to form proteins

What is the structure and function of the nucleus?

Bound by a porous nuclear envelope


Houses chromatin: DNA with associated proteins


Nucleus contains ribosomal RNA (rRNA)

What is the structure and function of ribosomes?

Organelles made of rRNA and protein


Found bound to the endoplasmic reticulum and free floating in the Cytoplasm


Sites of protein synthesis

rRNA

Produced by nucleus

Cell membrane

Polar heads oriented to the outside and inside of the cell


Heads face watery sides of Membrane


Hydrophobic tails oriented inward toward each other

Pathways of cellular respiration

Glycolysis


Citric acid (Krebs) cycle


Electron transport chain

Domains

Archaea


Bacteria


Eukarya

Prokaryotes: archaea and bacteria; Eukarya: humans and animals

What is the Endomembrane system?

It is a series of Membrane in which molecules are transported in the cell


It consists of the nuclear envelope, endoplasmic reticulum, Golgi apparatus, lysosomes, and vesicles

What is the Endomembrane system?

It is a series of Membrane in which molecules are transported in the cell


It consists of the nuclear envelope, endoplasmic reticulum, Golgi apparatus, lysosomes, and vesicles

Biodiversity

Total number of different species in an ecosystem

Standard error

The value that describes how far off an average could be

Endoplasmic reticulum

Proteins and lipids are manufactured here

Rough endoplasmic reticulum

Studded with ribosomes used to make proteins

Smooth endoplasmic reticulum

Lacks ribosomes but aids in making carbohydrates and lipids

Golgi apparatus

Flattened stacks that process, package, and deliver proteins and lipids from the ER

Lysosomes

Membranous vesicles made by the Golgi that contain digestive enzymes

Used to digest substances into simple subunits

Vesicles

Small membranous sacks used for transport

What is the cytoskeleton?

A series of proteins that maintain cell shape, as well as anchors and/or moves organelles in the cell


Made up of 3 fibers: large microtubules, thin actin filaments, and medium-sized intermediate filaments

Aids in cell division, structural support, and anchors organelles

Microtubules

Large filaments organized by the centrosome

Actin filaments

Long thin fibers that occur in bundles

Intermediate filaments

Differ in size and structure in different cells

What are cilia and flagella?

Both are made of microtubules (i.e., spindle fibers in Mitosis)


Both are used in movement


Cilia are about 20X shorter than flagella

Flagella

Long; aid in movement

Cilia

Protect from bacteria in air (i.e., nose)

What are cell junctions?

Junctions between the cells of human tissue that allow them to function in a coordinated manner. 3 main types:


Adhesion


Gap


Tight

Adhesion junctions

Mechanically attach adjacent cells (common in skin cells)

Tight junctions

Connections between the plasma membrane proteins of neighboring cells that produce a zipper-like barrier

Common in digestive system and kidney where fluids must be contained to a specific area

Tight junctions

Connections between the plasma membrane proteins of neighboring cells that produce a zipper-like barrier

Common in digestive system and kidney where fluids must be contained to a specific area

Tight junctions

Connections between the plasma membrane proteins of neighboring cells that produce a zipper-like barrier

Common in digestive system and kidney where fluids must be contained to a specific area

Gap junctions

Communication portals between cells; channel proteins of the plasma membrane fuse, allowing easy movement between adjacent cells

What do Mitochondria do and what do they look like?

Highly folded organelles in eukaryotic cells


Produce energy in the form of ATP


Thought to be derived from an engulfed prokaryotic cell


In Cytoplasm

People who exercise = more Mitochondria

Cristae

Folds on the inner membrane of Mitochondria where ATP production occurs

Negative feedback

The primary mechanism for maintaining homeostasis


The output of the system dampens the original stimulus


Has 2 components: sensor and control center

What is homeostasis?

It is the ability to maintain a relatively constant internal environment in the body


The nervous and endocrine systems are key in maintaining homeostasis


Changes from normal tolerance limits result in illness or even death

Temperature, blood pressure, pH, blood sugar, heart rate

Positive feedback

A mechanism for increasing the change of the internal environment in one direction


An example is the secretion of oxytocin during birth to continually increase uterine contractions


Can be harmful such as when a fever is too high and continues to rise

What are the mechanisms for maintaining homeostasis?

Negative feedback: the output of the system resolves or corrects the original stimulus


Positive feedback: brings about an increasing change in the same direction as the original stimulus

Chloroplasts and Mitochondria

2 organelles that probably evolved after a large prokaryotic cell engulfed smaller prokaryotic cells

Enzymes are important for cellular respiration and many activities in the cell

Most enzymes are proteins


Enzymes are often named for the molecules that they work on, called substrates


Enzymes are specific to what substrate they work on


Enzymes have active sites where a substrate binds


Enzymes are not used up in a reaction but instead are recycled


Some enzymes are aided by nonprotein molecules called coenzymes

Speed up reactions

The substrate of an enzymatic reaction

Is another name for the reactant

In cell division, centrioles

Form spindles for mitosis

Chromatin

DNA - form of threads; inside nucleus

What is cellular respiration?

Production of ATP inside a cell


Includes glycolysis, citric acid cycle (Krebs cycle), and electron transport chain

What is cellular respiration?

Production of ATP inside a cell


Includes glycolysis, citric acid cycle (Krebs cycle), and electron transport chain

Glycolysis

Occurs in the Cytoplasm


Breaks glucose into 2 pyruvate


NADH and 2 ATP molecules are made


Does not require oxygen

Citric acid cycle (Krebs cycle)

A cylindrical pathway that occurs in the Mitochondria


Produces NADH and 2 ATP


Releases carbon dioxide as a waste product


Hydrogen and electrons are carried away by NADH

The fatty acids of lipids

Yield intermediate molecules that can enter the citric acid cycle

The digestion of fats

Produces glycerol which can be converted to pyruvate to enter glycolysis

Electron transport chain

Series of molecules embedded in the mitochondrial membrane


NADH made in steps 1 and 2 carry electrons here


32-34 ATP are made depending on the cell


Requires oxygen as the final electron acceptor in the chain


Part of cellular respiration; involves high energy electrons passing through a series of carriers that harvest their energy in order to make ATP

Endosymbiosis

The process by which certain organelles may have arisen from engulfed prokaryotic cells

What other molecules besides glucose can be used in cellular respiration?

Other carbohydrates


Proteins


Lipids

The substrates on the left side of an arrow

In a chemical equation are known as reactants

The substrates on the left side of an arrow

In a chemical equation are known as reactants

How can a cell make ATP without oxygen?

Fermentation: occurs in the Cytoplasm, doesn't require oxygen, involves glycolysis, makes 2 ATP and lactate in human cells, can give humans a burst of energy for a short time

Cell division

Restores the amount of surface area needed for adequate exchaof materials

Important components of metabolism

Coenzymes


Enzymes


Cellular respiration

Pinocytosis

When fluids are brought into a cell

4 major tissue types

Connective


Muscular


Nervous


Epithelial

4 major tissue types

Connective


Muscular


Nervous


Epithelial

Connective tissue

Binds and supports parts of the body


Has specialized cells, ground substance, and protein fibers


Ground substance is non-cellular and ranges from solid to fluid


Ground substance and protein fibers together make up the matrix of the tissue

3 main types of connective tissue

Fibrous


Supportive


Fluid

Fibrous connective tissue

2 types: dense and loose, but both contain fibroblast cells with a matrix of collagen and elastic fibers


Loose fibrous connective tissue is found in supporting epithelium and many internal organs


Adipose tissue is a special, loose fibrous tissue where fat is stored

Supportive connective tissue: cartilage

Cells are in chambers called lacunae


Matrix is solid but flexible


3 types distinguished by types of fibers: hyaline cartilage, elastic cartilage, and fibrocartilage

Hyaline cartilage

Fine collagen fibers


Location: nose, ends of long bones, and fetal skeleton

Elastic cartilage

More elastic fibers than cartilage fibers


Location: outer ear

Fibrocartilage

Strong collagen fibers


Location: disks between vertebrae

Supportive connective tissue: bone

Cells are in chambers called lacunae.


Solid and rigid matrix is made of collagen and calcium salts


2 types distinguished by types of fibers: compact and spongy

Compact fibers

Made of repeating circular matrix called osteons which contain the hard matrix, living cells, and blood vessels


Location: shafts of long bones

Spongy fibers

An open latticework with irregular spaces


Location: ends of long bones

Fluid connective tissue: blood

Made of fluid matrix called plasma and cellular components that are called formed elements (3 of them)

Red blood cells

Erythrocytes - Cells that carry oxygen

White blood cells

Leukocytes - cells that fight infection

Platelets

Thrombocytes - pieces of cells that clot blood

Fluid connective tissue: lymph

Matrix is a fluid called lymph


White blood cells congregate in lymph nodes

Muscle tissue

Allows for movement in the body


Made of muscle fibers/cells and protein fibers called act and myosin


3 types: skeletal, smooth, and cardiac

Flesh/meat - smooth and cardiac = involuntary control

Muscle tissue: skeletal

Appearance: long, cylindrical cells, multiple nuclei, striated fibers


Location: attached to bone for movement


Nature: voluntary movement

Muscle tissue: smooth

Appearance: spindle-shaped cell with one nucleus, lacks striations


Location: walls of hollow organs and vessels


Nature: involuntary movement

Muscle tissue: cardiac

Appearance: branched cells with a single nucleus, striations with darker striations called intercalated disks get cells


Location: heart


Nature: involuntary movement

Muscle tissue: cardiac

Appearance: branched cells with a single nucleus, striations with darker striations called intercalated disks get cells


Location: heart


Nature: involuntary movement

Nervous tissue

Allows for communication between cells through sensory input, integration of data, and motor output


Made up of 2 major cell types: nuerons and neurol