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17 Cards in this Set
- Front
- Back
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What are the main causes of malabsorption?
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1) Pancreatic insufficiency due to chronic pancreatitis
2) Coeliac dz 3) Extensive small bowel resection 4)Crohn's disease |
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Man just came back from SE Asia and developed malabsorption weeks after acute diarrhoeal infection. What condition does he have and what treatment will you give him?
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Tropical Sprue
Tetracycline, folic acid and B12. |
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Which malabsorption diseases show villous atrophy?
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Coeliac dz
Tropical sprue Giardiasis Whipple's disease |
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What is the cause of Whipple's disease?
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Tropheryma whippeli
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What is coeliac disease?
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Villous atrophy due to gliaden fraction in gluten
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Which is the most common malignant tumour in the small intestine?
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Primary Lymphoma
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How do you detect T cell lymphoma and B cell lymphoma in SI?
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T cell lymphoma - CD3 +ve
B cell lymphoma - CD20 +ve |
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What are the causes of appendicitis?
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Most cases of appendicitis arise due to obstruction and infection.
Obstruction: faecolith, appendix tumour, foreign body, gallstone. Infection with virus etc |
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What are the consequences of appendicitis?
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Perforation --> peritonitis
Localised abscess |
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What histological changes are seen in celiac disease?
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Villous atrophy
Crypt hyperplasia Lymphoplasmocytic infiltrate Increased intraepithelial lymphocytes |
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What are the main causes of malabsorption?
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Pancreatic insufficiency due to chronic pancreatitis
Crohn's disease Celiac disease Extensive small bowel resection |
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Man just returned from SE Asia. He has malabsorption after having diarrhoea. What disease does he have and what treatment shld be given to him?
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Tropical sprue
Tetracycline, Vit B12 and folic acid. |
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What causes Whipple's disease?
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Tropheryma whippelii.
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What genetic defect is associated with celiac disease?
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HLA 2 & 8.
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How does malabsorption present?
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Failure to thrive
Steatorrhoea Anaemia Weight loss |
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How does bowel obstruction present?
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Colicky abdominal pain with distension. anorexia, N&V with relief. constipation
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What are the main causes of bowel obstruction?
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Hernia
Adhesion |
