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7 Cards in this Set
- Front
- Back
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3 Components of athersclerotic plaque
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1. Cell - SMC, Macrophages, T cells
2. ECM - Collagen, elastic fibers, proteoglycans 3. Lipid - Intra and extra-cellular |
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Atherosclerotic sites (vessels)
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Order of descending frequency:
Abdominal Aorta Coronary artrey Popliteal artery Internal carotids |
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Components of fibrous cap
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SMC
dense collagen |
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Necrotic center is composed of what?
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Cellular debris
cholesterol crystals foam cells |
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What are the consequences of atherosclerosis
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MI
CVA Aortic aneurysm peripheral vascular disease |
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Hyaline Arteriosclerosis
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Homogeneous hyaline thickening of the walls.
Basement membrane leaks plasma components across vascular endothelium. Excessive ECM by SMC. |
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Hyperplastic Arteriosclerosis
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"Onion-skin", Concentric, Laminated thickening of the wall.
SMC proliferation and duplicated basement membrane. Characteristic of malignant hypertension. (diastolic > 120mmHg) Necrotizing arteriolitis (Fibrinoid deposits and wall necrosis) |
