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57 Cards in this Set

  • Front
  • Back
Racial, inc melanin, normal cell #
Physiolgic Pigmentation
Inc in melanin, normal cell #
Post-inflammatory pigmentation
Inc in melanin, normal cell #
FLAT, uniformly pigmented, well-defined, normal surface texture, lower lip
Labial melanotic macule
Chronic sun exposure, age, inc # of melanocytes
Well-demarcated, multiple, hands/face/arms
Solar Lentigo (liver spots)
Change in pigmentation of face due to pregnancy and oral contraceptives
Sun exposed skin, inc melanin, FLAT, women
Melasma (mask of pregnancy)
“Stucco keratosis” greasy look, warty, benign
Diff Dx: Melanoma
TMT: cosmetic
Not the same as seborrheci dermatitis
Seborrheic keratosis
greasy warty
Seborrheic keratosis
(Pigmented skin in flexural areas, most benign, monority assoc w/ underlying condition)

Pigmented – Neoplastic
Acanthosis nigricans)
Benign, flat/raised pigmented, <6 mm
One subtype to know: Spitz is more common in young women, looks bad, pink/red lesion
Melanocytic nevus (mole)
3rd most common skin cancer, (BCC 1st, SCCA 2nd)
Risk factors: family Hx, light skin, Hx of childhood sunburns
Warning signs: Asymmetry, Boarder irreg, Color mottled, Diameter >6mm
“In-situ phase” – superficial spreading, most common, does not metastasize
Vertical growth phase – invasive, metastatic potential, (80% die if deeper than 4mm)
Nodular – arises & invades rapidly, usually dark
- “melanoma-in-situ,” sun exposed skin, elderly, fair skin, large, slow expanding
Lentigo maligna
under nails, palms, soles, mucosa – most common melamnoma in Black & Asian
Prognosis – depth (Clark’s levels & Breslow), worst sites Back, Arm, Neck, Scalp
TMT: surgical excision (+/- lymph node removal/chemo)
Acral Lentiginous
Esp palate & gingiva, 20% no pigment
Immune-mediated Pigmented
Oral melanoma
pigmenetary loss with local patches
Syndrome-associated Pigmented
CafÈ-au-lait macules (melanin pigmented patches of skin) syndromes:
Neurofibromatosis I
McCune Albright
Adrenal corical deficeiency , overproduction of ACTH/MSH
Bronzing of skin
Signs of hypoadrenocortism
Addison’s Disease
Blue color, blanch on diascopy Lower lip, ventral tongue
Malignant proliferation of basal layer, sun exposure, some NBCCS related
Most common skin cancer, most head & neck, 30% of whites by 55 y/o
“Rodent ulcer”, variable, borders raised, ulcer in middle, telangectasias
Slow growing, rarely metastasizes, rarely fatal
TMT: surgical excision (5-10 mm margins)
Basal Cell Carcinoma
Chronic sun exposure. Lower lip (actinic chelitis), ears, forehead, nasal bridge
Appearance variable
Prog: not as good as BCC, worse than oral SCCa
Squamous cell carcinoma
HHV-8 related, classic, endemic, immunodef subtypes
Kaposi’s sarcoma
Rare red variant of skin carcinoma. Looks like SCCa,
Significant percentage have metastasized @ Dx.
Much more aggressive than SCCa and Basal cell.
Merkel cell carcinoma
Inflammation of dermis around mouth w/ clear zone around lips, women
Caused by topical steroids, cosmetics, and maybe tartar control toothpaste.
Perioral dermatitis
inflam hair follicle, Staph/candida, in-grown hairs (shaving)
Dilated superficial blood vessels
Related syndromes
CREST syndrome
Too much sebum being produced à crusty, scaly, oily looking skin
Seborrheic dermatitis
acute superficial cellulitis from strep.
strawberry tongue
Scarlet Fever
Tetracycyline/minocycline root staingin
Follicular hyperkeratosis,
follicular bacterial production,
inflammatory process in involving hair follacles.

Multifactorial, Instability of vessels
Hot beverage, alcohol, spices
Erythema, esp cheeks
Bulbous leasions of nose
Silvery looking scales like fish. Koebner’s reaction
2% population
Defect in control of keratinocyte proliferation
Well defined erythematious plaque
- “infantile eczema”
Immediate allergic reactions to things.
Very common in infants, most outgrow it.
TX: keep skin moist
Atopic dermatitis
– also a mucocutaneous disease.
Significant percentage have skin lesions.
Red to purple polygonal shaped surfaces.
Redish looking lesions,
fingernail changes
Lichen planus
RARE, Autosomal recessive, inablitily to repair UV Damage
1000-4000 x higher incidence of cancer
Subnormal intelligence
Xeroderma pigmentosum
inherited, bad smell, Greasy
Small % in mouth
Gingiva or hard palate
2-3 mm white papules on oral keratinzed tissue
Darier’s disease (follicular keratosis)
Enlargement of bone in area
Klippel-Trenaunay-Weber syndrome (angiohypertrophy syndrome)
Enlargement of bone in area
low grade variant of SCCA
Rolled borders, keratin plug in middle
10% vermillion border of lip (usually lower)
HPV, chemical carcinogens
Premalignant change of skin – small % develop into SCCA
Rough scaly oveal plaques
Light skinned
Forehad, cheeks, lower lip, ear, lateral neck
Actinic keratosis (lip=actinic chelitis)
Yelowish plauques, macules
Esp. upper eyelids
Tx: none
Umbilicated papules
Transmitted by direct contact
White to flesh colored, autoinnoculate
Viral (poxvirus)
Micro: moluscum bodies (viral inclusions)
Molluscum contagiosum
“boil” – deep infection of hair follicle
Staph aureus
Danger zone of face – cavernous sinus thrombosis
Verruca vulgaris
hangy looking gross thing
“Skin tag”
Acrochordon (Skin tag)
rare genetic syndrome, mental retardation sesiures angiofibomas. Potato looking thing in brain
fibrous papules on gingiva
enamel pitting on anteriors
Shagreen skin patches
Hypopigmented areas on skin (ashleaf spots)
Cardiac Rhabdomyomas
Angiofibromas of Tuberous sclerosis
Inherited, multiple small papules around facial orifices (hamartomas of hair follicles)
Warty appearing growths on dorcal hand
Palmar-plantar keratosis
Benign polyps of intestines
Breast cancer
Thyroid adenomas/carcinomas
Multiple hamartoma syndrome (Cowden Syndrome)
Oral cavity= “primary herpetic gingivostomatitis”
Vescicles on attached and unattached mucosa
Generalized gingival erythema
Primary Herpes
only on attached gingiva and hard palate
multiple vesciles, then ulcers
Secondary Herpes
Post herpetic nerualgila
Ramsay-Hunt syndrome
Facial and auditory nerves
Facial paralysis
Ear vescicles
Tinnitius, vertigo, deafness
V-1 involvement risk of ocular damage
Rare pulpal necrosis
Herpes zoster –shingles
strep or staph. Superficial bacterial skin infection
highly contagious
reaction to some foreign agent – allergen, etc.
Contact dermatitis
Acute onset
not chronic (self limiting)
Target (Bull’s eye) skin lesions
Hemorrhagic crusting of lips
Erythema multiforme
Erythema Multiforma variants:
Erythema multiforme Minor
Most cases
Skin +/- oral

Erythema multiforme Major (aka Stevens-Johnson syndrome)
Skin +/- oral + ocular or genital mucosa
Diffuse slouging of all skin/mucosa
High mortality
TEN (Toxic Epidermal Necrolysis)
will/could kill you
Oral lesions preceed skin lesions
+ Nicolski’s sign
Pemphigus vulgaris
– hardened skin
Raynaud’s phenomenon
Claw like appearance
Fibrosis of salivary glands – xerostomia
widening of PDL
Resorption of condylar head, ramus, coronioid
mild variant of scleroderma
Cacinosis cutis
Raynaud’s Phenomenon
Esophageal dysfunction
rubber man syndrome
Inherited defect in collagen formation