Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
8 Cards in this Set
- Front
- Back
|
Prevention of developement of resistance in tuberculosis |
Rifampin Isoniazid Pyrazinamide Ethanbutol 2 for 4 = 4 drugs for 2 months followed by 2 drugs(isoniazid and rifampin) for 4 months |
|
|
Isoniazid |
Isolated ranger middle lobe bullet hole = primary TB Sleeping guy = treat latent infection Mycolic acid cacti on wall Mycobacteria cowboy shot off wall = inhibits mycolic acid production Aggravating G tailed cat = Activated by catalase-peroxidase (silencing it causes to have resistance) |
|
|
Isoniazid Side effects |
Bandit in stockings and gloves = May cause peripheral neuropathy Slow acetyl-gunslinger = Isoniazid is normally metabolized by liver N-acetyltransferase - slow acetylaters have a higher risk of side effects Pair of dice= pyridoxine (vitamin B6) excretion - addition of B6 prevents peripheral neuropathy Motion lines = may cause seizures COw liver spot = hepatotoxicity Raised LFT flag = causes asymptomatic rise in aminotransferase Lupus wolf = lupus can happen MUD PILES = anion gap metabolic acidosis Broken chrome bumper = inhibits Cytochrome P450 |
|
|
Rifampin |
The Rifle Speeding chrome bumper = rifampin activated cytochrome P450 Shot RNA track switch = binds DNA dependant RNA polymerase Meningitis mohawk = Neisseria meningitidis H-plane = Maemophilus influenzae |
|
|
Rifampin side effects |
Cow Liver = hepatotoxicity Puking orange = produce orange body fluids |
|
|
Ethambutol |
Ethel the horse whisperer Arabian horse at carbohydrate wall after it knocks some of it down = blocks arabinosyl tranferase, inhibiting carbohydrate formation at the cell wall Halt! the horse = bacteriostatic |
|
|
Ethambutol |
Red-green blinders Optic neuritis (loss of visual acuity, red-green color blindness) DEgeneration of the macula
central scotoma |
|
|
Pyrazinamide |
The pyro knitting Needles = causes hyperuricemia and needle shaped uric acid crystal formation Yarn ball on toe = may precipitate gout attacks Cow Liver = hepatotoxicity |
