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6 Cards in this Set

  • Front
  • Back

Trifluidine

Less toxic than idoxuridine and vidarabine


Transient burning and stinging


Contact dermatitis


Corneal punctate keratopathy and edema


Conj. hyperemia and chemosis


Impaired stromal wound healing


Keratitis sicca


Punctal narrowing


Increased IOP

Ganciclovir

Blurred vision


Ocular irritation


Punctate keratitis


Conjunctival hyperemia

Acyclovir

Topical


*Most common s/e are punctate superficial keratitis (10%) and burning and stinging on instillation (4%)



Very safe drug, SE frequent in patients with renal impairment



Common - nausea, vomiting, diarrhea, abdominal pain



Other - skin rash, photosensitivity, HA, dizziness, hallucinations, lethargy, confusion and seizures



Rare - anemia, leukopenia, thrombocytopenia, increases in blood urea and creatinine, acute renal failure, reversible increases in bilirubin and liver enzymes, hepatitis and jaundice

Valacyclovir

Similar to acyclovir



Acyclovir:


Topical


*Most common s/e are punctate superficial keratitis (10%) and burning and stinging on instillation (4%)



Very safe drug, SE frequent in patients with renal impairment



Common - nausea, vomiting, diarrhea, abdominal pain



Other - skin rash, photosensitivity, HA, dizziness, hallucinations, lethargy, confusion and seizures



Rare - anemia, leukopenia, thrombocytopenia, increases in blood urea and creatinine, acute renal failure, reversible increases in bilirubin and liver enzymes, hepatitis and jaundice

Famciclovir

Most common side effects - HA, nausea, and GI disturbances



Other side effects - fatigue, pruitus, paresthesia, migraine and dysmenorrhea

Ganciclovir - Vitrasert

*Eye pain, swelling, redness or watering


*Severe burning or itching of your eyes


*Vision changes, increased sensitivity to light


*Tunnel vision, problems with peripheral (side) vision


*Seeing flashes of light, halos around lights or "floaters" in vision


*White patches on your eyes


*Cloudiness in the pupils or iris of your eyes


*Bleeding, oozing, or crusting of your eyes


*Sudden vision loss



Less serious side effects


*Blurred vision (may last up to 4 wks after implant)


*Mild eye irritation


*Increased tearing