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What SNRI has the prominent side effect of hypertension, and a short half-life (less than 24 hours, even an extended release formula)?

Venlafaxine (Effexor)

What SNRI Can treat depression as well as help with chronic pain conditions, such as neuropathic pain, or fibromyalgia?

Duloxetine (Cymbalta)

What are the effects of boosting norepinephrine?

Increased energy and focus