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74 Cards in this Set

  • Front
  • Back
The right coronary artery supplies the SA node what percent of the time? The AV node?
55%
90%
What is the primary treatment in the bradycardic patient who is unstable?
Transcutaneous pacing
Atropine to treat bradycardia is not useful in what type of patient?
Cardiac transplant, they have no vagal support
What is the dose of atropine in bradycardia?
What can you give if atropine is unsuccessful?
0.5 mg every 5 mins, up to 3 mg total
Epinephrine and dopamine
Treatment of a patient with stable, narrow complex tachycardia with regular rhythm?
What is the most likely diagnosis if it converts?
Vagal maneuvers
Adenosine 6 mg, then 12mg, then 12 mg --- IV PUSH!

AVRT
Treatment of a patient with stable, narrow complex tachycardia with irregular rhythm?
What is the most likely diagnosis?
Control rate with dilt or B-blockers

Probably atrial fib or flutter, consider MAT
What drugs do you want to avoid in WPW?
AV nodal blockers, dilt and b-blockers
Treatment of a patient with stable, wide complex tachycardia with regular rhythm?
What is the most likely diagnosis?
If Vtach or uncertain rhythm, amiodarone 150 mg IV over 10 min. Prepare for cardioversion.

If known SVT, give adenosine
Treatment of a patient with stable, wide complex tachycardia with irregular rhythm?
What is the most likely diagnosis?
If afib with WPW, avoid b-blockers and diltiazem. Consider amiodarone. Get a consultant.

If torsades, give magnesium 1-2 grams.

If polymorphic ventricular tachycardia, cardiovert
What cardiac disorder is characterized by abnormalities that produce a wide variety of intermittent supraventricular tachyarrhythmias and bradyarrhythmias?

What is the treatment?
Sick sinus syndrome

Pacemaker placement
What are the variations of regular, narrow complex tachycardia?

Irregular?
Sinus tachycardia, atrial tachycardia
Atrial flutter
AVRT
AVnRT
Junctional tachycardia

Atrial fibrillation
MAT
What is the success rate of vagal maneuvers in SVT?
20-25%
Any patient with a ventricular rate >300 should raise suspicion for what syndrome?
Preexcitiation syndrome such as WPW
When can and can't you give adenosine, calcium channel blockers, and b-blockers in people with WPW.
Can give adenosine in narrow complex regular tachycardia
Never give B-blockers or diltiazem
How is atrial fibrillation or atrial flutter with WPW treated?
With cardioversion, but can also consider procainamide
What are the doses for treating rate control of Atrial Fibrillation in the ED?
Diltiazem?
Metoprolol?
Diltiazem: 15 mg once over 2 minutes with a continuous infusion at 5 mg/h

Metoprolol: 5 mg IV every 5 minutes up to 15 mg.
What happens to the PR interval in junctional rhythm? Where are the beats arising?
PR interval shortens
They start from the AV node.
What other rhythm can ventricular tachycardia be confused with?
SVT with aberrancy
What is the first line treatment for unstable ventricular fibrillation?
Stable?
2nd line in stable?
cardioversion
amiodarone 150 mg every 10 minutes up to 2 g
Next procainamide 50 mg/min
2nd line: Lidocaine
Treatment of torsades de pointes?
Magnesium sulfate 2 g IV over 60-90 minutes
Treatment of ventricular fibrillation?
Defibrillation: 360 J if monophasic, 200 J if biphasic
CPR
Check pulse

If it continues Amdiodarone 300 mg IV bolus or Lidocaine 1.5mg/kg IV followed by halving the dose for 2 more doses.
1st degree block is characterized by a PR interval > __ seconds.
0.20
Widened QRS complexes, wide S leads in lead 1, V5, V6, and triphasic QRS in V1 is seen in what disease?
RBBB
Describe EKG findings for LBBB.
Large and wide R waves - lead I, avl, v5, v6
Small R wave follwed by deep S wave - leads II, III, avf, and V1-V3
What do patients with Brugada syndrome present with?
Syncope
When is lidocaine used in cardiac arrhythmias?
2nd line to amiodarone for vfib and pulseless vtach
Beta Blockers with Beta only activity such as atenolol, esmolol, and metoprolol are better choices (less likely to causes side effects) for patients with history of what diseases?
asthma, copd, diabetes - they are B1 only and don't affect B2
How fast is the onset of labetolol?

What is the initial IV dose and subsequent dosing?
2-5 minutes

20 mg, then double dose if not responding
Other than typical beta blocker side effects such as nausea, vomiting, bronchospasm, hyperglycemia, what symptom can sotalol produce?
It has pro-arrythmic properties
What is the dosing of amioderone in pulseless vtach and vfib?
300 mg bolus, which can be followed with another 150 mg bolus
What are the side effects of long term amioderone usage?
Thyroid
Pulmonary fibrosis
Liver damage
corneal infiltrates
Amiodarone is contraindicated in people with what allergies?
shellfish, iodone

Amiodarone contains iodine
What is the dose for atropine in bradycardia? How does atropine work?
0.5mg IV every 5 minutes

It is anticholinergic - also could be called an antiparasympathetic
T/F Atropine can be used in the stable, bradycardic patient.
False
Describe the dosing and time of adenosine in SVT.
6 mg, then 12 mg 2 minutes later, and then 12 mg again 2 minutes later if not responding
Other than standard flushing, headache, chest pain, what side effect can adenosine have?
It may induce bronchospasm
What are the basic signs of digitalis toxicity?
mental status changes
confusion
ha
anorexia
n
v
weakness
visual disturbances
seizures
What electrolyte abnormality increased the risk of digoxin toxicity?
Hypokalemia
Dobutamine has activity against which receptors?
B1, B2

Increased cardiac output and decreased peripheral resistance up to 20 mcg/kg/min, above that will increase HR and induce arrhythmias.
Under what situations is dobutamine the preferred agent in cardiogenic shock?
septic shock with low cardiac output ... cold septic shock
cardiogenic shock
Dobutamine has activity against which receptors?
B1, dopamine, alpha
Epinephrine is a non-selective alpha and beta adrenergic agonist that is useful in what clinical scenarios?
Anaphylactic shock
Asthma exacerbation
Myocardial stimulant in cardiac arrest
What is the dose, concentration, and route of epinephrine to be used in asthma?
0.3 to 0.5 mg 1:1000 SubQ every 20 to 30 minutes
What drug is used when dopamine or epinephrine infiltrate?
Phentolamine (Regitine)
What receptors dose norepinephrine stimulate? How does this differ from epinephrine?
Alpha and Beta-1

Levophed does not stimulate B2
What is the starting dose of norephinephrine?
2mcg/min ... titrate by 1-2 mcg every 3-5 minutes

Max dose 30 mcg/min
What receptors dose phenylephrine stimulate? Therefore, what is the mechanism of action?
Primarily alpha receptors with minimal B1 or B2

Peripheral vasocontrictor
Name the preferred medication in these scenarios:

1) Septic shock patient with bradycardia

2) Septic shock with asthma exacerbation

3) Septic shock with severe tachycardia

3) Infiltration of IV with epinephrine
1) norepinephrine or possibly dobutamine...Not phenylephrine as it can cause reflex bradycardia

2) epinephrine

3) phenylephrine

4) Phentolamine
Define shock.
Shock is a circulatory insufficiency that creates an imbalance betweeen tissue oxygen supply (delivery) and oxygen demand (consumption).
What is the normal central venous/mixed veous oxygen saturation?
65 - 75 %
What situations shift the oxygen dissocation curve to the right?
decreased pH
increased co2
increased temp
increased 2,3 - DPG
What are the 4 factors that make up SIRS?
Temperature <36 or > 38
RR > 20
HR > 90
WBC > 12, <4, > 10% immature cells
Dopamine does what to vessels at a dose of 0.5 to 5 mcg/kg/min? At > 10 mcg/kg/min?
Vasodiliation

Vasoconstriction
What does vasopression work on when used in sepsis?
It is a pure vasoconstrictor
What receptors does isoproterenol work at?
B1 with minimal B2...Opposite of phenylephrine
What drug is receptor opposite of isoproterenol?
phenylephrine
What is the purpose of intubation during shock?
Decreased work of breathing
In shock:

You want to maintain artial O2 saturations > __%. Transfuse hgb if it is below __ g/dl.
93%
10
A goal directed approach to septic shock includes what variables?
Urine output >0.5 ml/kg/hr
MAPs 65 to 90
CVP 8 to 12
Sv02 > 70%
What is the advantage of LR over NS in shock patients?
LR can buffer acidosis
What is a safe pH in which bicarbonate can be used in sepsis? Why would you not want to use it before then?
<7.25

Shifts oxygen curve to left. Less O2 delivery.
What are some of the causes of coagulopathy in trauma?
Massive hemorrhage
Hypothermia
Consumption of clotting factors, platelets
Dilution of clotting factors
Massive blood transfusions
Hypocalcemai
Define class I,II, III and IV hemorrhage by percentages.
Class I: <15%
Class II: 15 - 30 %
Class III: 30 - 40%
Class IV: >40%
Bradycardia or lack of tachycardia can occur in up to 30% of patient with what type of bleed into this body cavity? Why?
Intrabdominal
Increased vagal tone
What is the concern for starting PPV in a patient who has not had sufficient IV fluids?
PPV in the setting of hypovolemia can diminish venous return and decrease cardiac output
What is the ratio of IV fluid to blood in the hemorrhaging patient?
3:1
In addition to pRBCs in massive trauma, what else is given and what is the ratio?
1:1:1
pRBCs, FFP, platelets
With suspected anaphylaxis, the single most important treatment in the ED is what?
epinephrine
What is the dose, route, and formula of epinephrine in anaphylaxic shock? What are second line therapies?
0.3 to 0.5 mg of 1:1000 dilution IM repeated every 5-10 minutes.

IV fluids, methylprednisolone (solumedrol 125 mg IV), benadryl 50 mg IV.
Explain the differences between IM and SC epinephrine in anaphylaxic shock?
IM is faster, more consistant than SC doses.
What is the next step if patient is refactory to IM epinephrine in anaphylaxic shock?
Epinephrine IV 100 mcg bolus, then drip at 1 -4 mcg/min
What are second line therapies and doses in anaphylaxic shock?
IV fluids, methylprednisolone (solumedrol 125 mg IV), benadryl 50 mg IV. H2 blockers, albuterol
What medications are given when discharging a patient with anaphylactic reaction?
Epipen
Benadryl for several days
Prednisone burst
Instructions
What medications are useful in treating angioedema related to ACEi use?
None really.

Antihistamines and steriods don't work because it is not an IgE response. Epinephrine has also not shown to be useful.