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12 Cards in this Set
- Front
- Back
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(-)ssRNA Paramyxoviridae virus
prodrome of fever, cough, conjunctivitis erythematous macular rash spreads from face down transmission by respiratory droplets highly contagious, esp. during prodrome live attenuated vaccine available |
Measles
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(-)ssRNA Paramyxoviridae virus
2 surface glycoproteins are hemagglutinin-neuraminidase and fusion protein classic prodrome is parotitis, possible complications include orchitis, meningitis, pancreatitis, and encephalitis does not involve skin rash transmission by respiratory droplets live attenuated vaccine available Ab to S antigen indicates current infection, Ab to V antigen (HN protein) indicates past infection |
Mumps
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(+)ssRNA Togaviridae virus
characteristics include variable rash, joint pain, lymphadenopathy, and fetal problems; greatest concern is the effect on the fetus classic triad of CRS is deafness, cataracts, and patent ductus arteriosus late onset effects include behavioral disorders |
Rubella
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ssDNA Parvoviridae virus
erythematous, macular rash bestowing "slapped cheek" appearance (erythema infectiosus, 5th disease) lytic infection of RBC precursor cells can lead to aplastic crisis other clinical manifestations include arthropathy and hydrops fetalis cases most commonly occur in the spring |
Erythrovirus B-19 (parvovirus)
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(+)ssRNA viruses of the Picornaviridae family
cause a variety of diseases (for this section notably herpangina, summer rash, and hand, foot and mouth disease) most infections in summer and fall transmitted by the fecal-oral route |
Enteroviruses (Coxsackie, Echo)
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dsDNA Herpesviridae virus
primary lesion is vesicular lesions in anterior of mouth; recurrent infections can present as clusters of vesicles around mouth and nose potential additional characteristics include genital lesions, keratitis, and encephalitis latent stage in the ganglia (viral DNA present, but no viral proteins) |
Herpes Virus 1
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dsDNA Herpesviridae virus
erythematous, maculopapular lesions progressing to vesicles, pustules and scabs latent phase in ganglia chickenpox is the primary infection, shingles (VZV) is the reactivation latency in ganglia important nosocomial infection in malignancy wards live attenuated vaccine available |
varicella zoster virus (shingles)
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dsDNA Herpesviridae viruses
associated w/ Roseola abrupt high fever and macular rash on face that spreads downward |
HHV-6 and HHV-7
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dsDNA Herpesviridae virus
causes Kaposi's sarcoma, common in AIDS patients |
HHV-8
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dsDNA Papovaviridae virus
causes warts on hands, feet, and genital areas transmitted by direct contact associated w/ cervical cancer |
Papillomavirus
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dsDNA Poxviridae virus
replication in cytoplasm, independent of host cell nucleus |
Smallpox
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unclassified poxvirus
dome shaped, translucent nodules transmitted by direct contact eosinophilic inclusion bodies in cytoplasm of infected cells no latent stage |
Molluscum Contagiosum
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