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10 Cards in this Set
- Front
- Back
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patient with HSV that requires extremely aggressive therapy
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neonate
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nucleoside analog similar to guanosine, but contains an acyclic sugar group
close to a perfect antiviral drug (specific, nontoxic) highly effective against HSV requires an HSV thymidine kinase to function **guanine derivative** |
acyclovir
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**regimen for acyclovir administration
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**three to five times a day
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ester prodrug of acyclovir
able to be given twice a day |
valacyclovir
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major difference among the different guanosine derivatives
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pharmacokinetics
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prodrug of penciclovir
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famciclovir
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guanosine derivative that is given to transplant patients
increased bone marrow suppression possible what is it's ester prodrug? |
ganciclovir
valganciclovir |
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topical antivirals (ocular or skin)
what patients should not recieve these drugs |
penciclovir
idoxuridine (ocular) trifluridine (ocular) vidarabine (ocular) podofilox imiquimod pregnant women should not use these drugs |
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pyrimidine nucleoside mimic
incorporates iodine into elongating viral protein less selectivity than acyclovir between HSV and host cells |
idoxuridine
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drug that is synthesized and purified from plant families
severe reactions w/in 1st 2 weeks of treatment, including bleeding of skin burning, itching, and pain are experienced more by women used in treatment of external genital warts what is the cream that stimulates interferon alpha? |
podofilox
imiquimod |
