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23 Cards in this Set

  • Front
  • Back
three types of fungal diseases
mycotoxicoses
hypersensitivity diseases
colonization/infection
fungal infections of the stratum corneum w/ little or no inflammatory response
superficial mycoses
4 types of superficial mycoses
tinea (pityriasis) versicolor
tinea nigra
black piedra
white piedra
brown/black macules on palms and/or soles

superficial and asymptomatic

no host immune response

caused by Exophiala wernickii
Tinea Nigra
scaly hypo- or hyperpigmented patches on neck, torso, and limbs

infection largely cosmetic

caused by Malassezia furfur
Tinea (pityriasis) versicolor
superficial fungal infection that appears as cream, yellow or beige nodules along the hair shaft

caused by Trichosporon sp.
White piedra
fungal infection of scalp hair causing hard, gritty, brown/black nodules firmly attached to hair shaft

caused by Piedraia hortae
black piedra
three genera of dermatophytes

they produce keratinase

transmission can be anthropophilic, zoophilic, or geophilic
Trichophyton
Microsporum
Epidermophyton
infection that is commonly called ringworm

caused by dermatophyte fungi
tinea
dermatophytosis of the glabrous skin of the face, trunk, and limbs

zoophilic and geophilic varieties are apt to cause inflammatory lesions

prevalent in warm, humid climates
tinea corporis (ringworm of body)
dermatophytosis of the plantar surface of the feet and toe webs

most common pathogens are T. rubrum and T. mentagrophytes
tinea pedis (athlete's foot)
dermatophytosis of the medial upper thighs and the inguinal, pubic, perineal, and perianal areas

most common pathogen is T. rubrum
tinea cruris (jock itch)
hyphal invasion of scalp spreads to hair follicle

caused by Microsporum and Trichophyton species

acute inflammation of hair follicle (favus)
tinea capitis
dermatophytosis of the facial beard area of men

most common agents are T. mentagrophytes and T. verrucosum
tinea barbae
common pathogen involved in fungal infection of the nail (tinea unguim)
Trichophyton rubrum
most common locations for subcutaneous mycoses
hands, feet, arms, legs

introduction following trauma
fungus found in soil, introduced into skin following trauma (eg. rose thorn)

causes chronic nodular and ulcerative lesions

bug?
lymphocutaneous sporothrichosis

Sporothrix schenckii
chronic, localized cutaneous to subcutaneous infection causing warty nodules at inoculation site w/ "cauliflower like" appearance
chromoblastomycosis
fungal infections that fluoresce under UV light during Wood's lamp exam

2 other tests used in diagnosis of superficial and cutaneous mycoses
Microsporum spp.

KOH prep and culture
treatment of superficial mycoses
treat w/ topical agents (cream or shampoo)
characteristic triad of indurated swelling, multiple sinus tracts, and localization on foot
mycetoma
treatment of cutaneous mycoses:
1) tinea corporis
2) tinea capitis and barbae
3) onychomycosis
4) hair infections
1) topical allylamines
2) systemic treatment
3) systemic treatment
4) oral griseofulvin
treatment of subcutaneous mycoses:
1) sporotrichosis
2) chromomycosis
3) mycetoma
1) saturated solution of KI
2) 5-fluorocytosine
3) varies (amphothericin B or aoles)