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8 Cards in this Set
- Front
- Back
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Drugs -
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Agents intended for use in the diagnosis, treatment, cure or prevention of disease. Drugs are rarely administered as a pure ingredient.
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Medicines -
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Allow the administration of drugs in a safe, efficient and convenient way. Medicines rarely contain drugs on their own, but instead require additives as well to turn them into dosage forms.
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Bioavailability -
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The relative AMOUNT of the administered drug that reaches 'systemic circulation' intact and the RATE at which this occurs.
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Excipients/ additives -
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Ingredients added with no therapeutic effect (e.g. flavour)
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Purpose of dosage forms:
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- Controls the accuracy of the dosage
- Convenient - easy to use and sell - Protects the drug if its unstable - Can deliver the drug at an appropriate rate - Packaging prevents contamination |
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What are the factors that influence what route of administration is chosen?
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- Body's protective barriers (e.g. a drug that can't cross the skin - can't be used as a cream)
- The drugs physical and chemical properties (degraded by acid - can't be used in GIT) - Clinical need - certain diseases may need certain administration - Patient preference - Prescribers inclination |
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Systemic routes of administration -
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- Enteral (through the GIT, e.g. oral or rectal)
- Parenteral (injections, IV) - Transmucosal (buccal, sublingual, nasal, vaginal, rectal) |
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Local routes of administration -
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- Skin (dermal)
- Mucosal (ophthalmic, nasal, otic) - Inhalation (respiratory) |
