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15 Cards in this Set

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ANA + peripheral pattern
SLE
ANA + diffuse pattern
nonspecific
SLE, drug-induced lupus, RA (low titer, normal elderly
ANA + speckled pattern
nonspecific
high titers in MCTD, low in normal elderly
ANA + centromere pattern
limited scleroderma (CREST), PBC
ANA + nucleolar pattern
scleroderma, Sjogren syndrome
anti-ds-DNA
SLE ONLY (60-75%)
is an indicator of dz activity
DO NOT find in drug-induced SLE
anti-Sm(ith)
SLE ONLY (25%)
anti-SS-A (Ro)
- SLE, neonatal SLE, Sjogren syndrome, ANA negative SLE.
- NOT seen in scleroderma
- assoc w/DR3
- neonatal lupus w/congenital heart block, Ab passive transfer from mom
anti-SS-B (La)
SLE, Sjogren syndrome (30%)
anti-U1-RNP
MCTD (100%), SLE
anti-histone
drug-induced lupus (95%) and SLE (25%)
- main use is to rule out drug-induced lupus
anti-topoisomerase 1
Diffuse scleroderma
anti-mitochondrial Ab
PBC
anti-Jo
polymyositis with mechanic's hands, arthralgias, ILD
anti M12
anti PM1
sclerodema-myositis overlap syndromes