Rhds Exam - Chapter 1

Front 1

route of administration of biologics

Back 1

injection or infusion

Front 2

What is the brand name for a biologic used for the treatment of rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, psoriasis?

Back 2

Enbrel

Front 3

What is the brand name for etanercept

Back 3

Enbrel

Front 4

What is the brand name for a medication that is a synthetic version of a protein developed from the saliva of the Gila monster??

Back 4

Byetta

Front 5

What is the brand name for trastuzumab?

Back 5

Herceptin

Front 6

What is the brand name for a biologic used for the treatment of breast cancer?

Back 6

Herceptin

Front 7

What biologic medication is used for the treatment of diabetes?

Back 7

Byetta

Front 8

What is the brand name for quadrivalent HPV Types 6, 11, 16, and 18 recombinant vaccine?

Back 8

Gardasil

Front 9

What is the brand name for a biologic vaccine for prevention of cervical cancer, vulvar cancer, vaginal cancer, genital warts, and various precancerous genital lesions caused by certain types of human papillomavirus

Back 9

Gardasil

Front 10

What is the brand name for infliximab?

Back 10

Remicade

Front 11

What biologic medication is used for the treatment of Crohn disease, ulcerative colitis, rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, plaque psoriasis?

Back 11

Remicade

Front 12

What 2 terms refer to products that are claimed to have the same mechanism of action and treat the same clinical indications as the original biologic?

Back 12

"biosimilar" or "follow-on biologic"

Front 13

Name 3 follow-on biologics that are marketed in third-world countries and are in development in the US?

Back 13

erythropoietin, growth hormone, & insulin

Front 14

What are three classes of commonly used medications that are increasing in popularity and market share?

Back 14

Biologics (biotics), nutraceuticals, combination drugs

Front 15

The FDA defines _______________________________ as “therapeutic and diagnostic products that combine drugs, devices, and/or biological products.”

Back 15

combination drugs

Front 16

a combination of ezetimibe (brand name Zetia) and the statin drug simvastatin (brand name Zocor), used in the treatment of dyslipidemia

Back 16

Vytorin

Front 17

a combination of rosiglitazone (Avandia) and glimepiride (Amaryl), used in the treatment of type 2 diabetes

Back 17

Avandaryl

Front 18

combination of repaglinide (brand name Prandin) and metformin HCl (Fortamet), used in the treatment of type 2 diabetes

Back 18

Prandimet

Front 19

combination of atorvastatin (Lipitor) to treat hypercholesterolemia and amlodipine (Norvasc) to treat hypertension

Back 19

Caduet

Front 20

combination of amlodipine (Norvasc) and valsartan (Diovan), used in the treatment of hypertension

Back 20

Exforge

Front 21

Which class of medications does not have to be approved by the FDA before marketing?

Back 21

nutriceuticals

Front 22

One notable example of a nutraceutical is the use of ______________ in pregnant women to help prevent neural tube defects in the baby

Back 22

folic acid

Front 23

Name the nutraceutical:
There is evidence that these fatty acids lower triglycerides, reducing the risk of death, heart attack, dangerous heart rhythms, and strokes in people with known cardiovascular disease & slow the buildup of plaques.

Back 23

Omega-3

Front 24

Name the nutraceutical:
microorganisms that may help with digestion and offer protection from harmful bacteria

Back 24

Probiotics

Front 25

Name the nutraceutical:
an antioxidant that may help maintain a healthy cardiovascular system

Back 25

Coenzyme Q10

Front 26

Name the nutraceutical:
may enhance the immune system, contribute to cardiovascular health, and reduce cancer risk

Back 26

Antioxidants

vitamin E, vitamin C, beta-carotene, coenzyme Q10

Front 27

In terms of the FDA, what does NME stand for?

Back 27

new molecular entity

Front 28

What is a new molecular entity used to treat schizophrenia?

Back 28

Latuda

Front 29

What medication class does Botox belong to?

Back 29

biologics

Front 30

Which of the following is responsible for the rise in popularity of combination drugs?
a. Government requirements and restrictions
b. Consumer convenience and safety
c. Manufacturer convenience and safety
d. Electronic health records

Back 30

b. Consumer convenience and safety

Front 31

The combination of atorvastatin and amlodipine marketed as which of the following drugs?
A. Jalyn
B. Caduet
C. Advil
D. ASA

Back 31

B. Caduet

Front 32

All of the following are considered biologic medications except which answer below?
A. Humulin
B. Enbrel
C. Herceptin
D. Protonix

Back 32

D. Protonix

Front 33

What is one of the primary routes of biologic administration?
A. Tablets
B. Topical
C. Injection
D. Inhalation

Back 33

C. Injection

Front 34

To what class of medication does Coenzyme Q10 belong?
A. Combination
B. Biosimilar
C. Nutraceutical
D. New molecular entity

Back 34

C. Nutraceutical

Front 35

What is the expected result when prescribing probiotics?
a. Lower blood pressure
b. Aid with digestion
c. Treat restless leg syndrome
d. Treat obstructive sleep apnea

Back 35

b. Aid with digestion

Front 36

Krystexxa is a new biologic approved by the FDA in 2010. What is the generic name for this drug?
a. Ibuprofen
b. Gardasil
c. Pegloticase
d. Pantoprazole

Back 36

c. pegloticase

Front 37

Actemra

Back 37

tocilizumab

Rheumatoid arthritis

biologic

Front 38

Ampyra

Back 38

dalfampridine

multiple sclerosis

NME

Front 39

Vpriv

Back 39

velaglucerase alfa

Gaucher disease--a genetic disease in which a fatty substance (lipid) accumulates in cells and certain organs

NME

Front 40

Xiaflex

Back 40

Collagenase clostridium histolyticum

Dupuytren contracture

biologic

Front 41

Asclera

Back 41

polidocanol

Varicose veins

NME

Front 42

Carbaglu

Back 42

carglumic acid

Chronic hyperammonemia

NME

Front 43

Natazia

Back 43

estradiol valerate; estradiol valerate dienogest

Oral contraception

NME

Front 44

Lumizyme

Back 44

alglucosidase alfa

Pompe disease -- an inherited disorder caused by the buildup of a complex sugar called glycogen in the body's cells. The accumulation of glycogen in certain organs and tissues, especially muscles, impairs their ability to function normally.

biologic

Front 45

Jevtana Kit

Back 45

cabazitaxel

Metastatic prostate cancer

NME

Front 46

Prolia

Back 46

denosumab

Osteoporosis

biologic

Front 47

Pradaxa

Back 47

dabigatran etexilate mesylate

Prevent blood clots and strokes in atrial fibrillation

NME

Front 48

Dulera

Back 48

formoterol fumarate; mometasone furoate

Asthma