Review: Immune System And Complement

Front 1

Organs of the Immune system

How many categories?

Back 1

2

List

Hint 1

Primary lymphoid and Secondary lymphoid organs

Front 2

Organs of the immune system

2 Categories

Back 2

Primary

Secondary lymphoid organs

Front 3

Organs of the immune system

___________

Secondary lymphoid organs

Back 3

Primary lymphoid organs

How many?

Hint 3

2

Front 4

Primary lymphoid organs

How many?

Back 4

2

List

Hint 4

Thymus

Bone marrow

Front 5

2 Primary lymphoid organs

Back 5

Thymus

Bone marrow

Front 6

2 Primary lymphoid organs

___________

Bone marrow

Back 6

Thymus

What occurs in this organ?

Hint 6

T Cell development

Front 7

2 Primary lymphoid organs

Thymus

What occurs in this organ?

Back 7

T cell development

Front 8

2 Primary lymphoid organs

Thymus

_________________

Back 8

Bone marrow

What occurs in this organ?

Hint 8

B cell development

Front 9

2 Primary lymphoid organs

Bone marrow

Back 9

B cell development

Front 10

Organs of the immune system

Primary

______________

Back 10

Secondary lymphoid organs

How many examples?

Hint 10

2

Front 11

Secondary lymphoid organs

How many examples?

Back 11

2

List

Hint 11

Spleen

Lymph nodes

Front 12

Secondary lymphoid organs

2 examples

Back 12

Spleen

Lymph nodes

Front 13

Secondary lymphoid organs

What occurs in these organs?

Back 13

Contact with Ag

Lymphocyte activation

Front 14

Secondary lymphoid organs

What occurs in these organs?

2

Back 14

Contact with Ag

Lymphocyte activation

Review: 2 examples of secondary lymphoid organs

Hint 14

Spleen

Lymph nodes

Front 15

B lymphocytes, what do they develop into?

Back 15

Plasma cells

What do they make?

Hint 15

Ab

Front 16

Plasma cells

What do they make?

Back 16

Ab

Made by ______, which are derived from ________

Hint 16

Plasma cells

Derived from B lymphocytes

Front 17

T lymphocytes

How many main functions?

Back 17

2

List

Hint 17

Cell-mediated immunity

Regulate immune response

Front 18

T lymphocytes

2 functions

Back 18

Cell-mediated immunity (Direct/Indirect role?)

Regulate immune response

Hint 18

Direct role

Front 19

T lymphocytes

_______________

Regulate immune response

Back 19

Cell-mediated immunity

Role?

Hint 19

Direct role

Front 20

T lymphocytes

Direct role in cell-mediated immunity

Cells involved

How many?

Back 20

2

List

Hint 20

CTL

TH1

Front 21

Direct role in cell-mediated immunity

2 Cells are involved

Back 21

CTL

TH1

Front 22

Direct role in cell-mediated immunity

2 Cells are involved

_____

TH1

Back 22

CTLs

What do they do?

Hint 22

Lyse virus-infected and tumor cells

Front 23

CTLs

What do they do?

Back 23

Lyse virus infected and tumor cells

Front 24

Direct role in cell-mediated immunity

2 Cells are involved

CTL

______________

Back 24

TH1

What do they do?

Hint 24

Produce cytokines

Type IV hypersensitivity

Front 25

TH1

What do they do?

Back 25

Produce Cytokines

Type IV hypersensitivity

Front 26

T lymphocytes

Direct role in cell-mediated immunity

___________________

Back 26

Regulate immune response

How many cells are involved?

Hint 26

3

Front 27

T lymphocytes

Regulate immune response

How many cells are involved?

Back 27

3

List

Hint 27

TH1

TH2

T reg

Front 28

T lymphocytes

Regulate immune response

3 cells involved

Back 28

TH1

TH2

T reg

Front 29

T lymphocytes

Regulate immune response

_______

TH2

T reg

Back 29

TH1

Function

Hint 29

Help cell-mediated responses

Front 30

TH1

Function

Back 30

Help Cell-mediated responses

Front 31

T lymphocytes

Regulate immune responses

TH1

______

Treg

Back 31

TH2

Function

Hint 31

Help Ab responses

Front 32

T lymphocytes

Regulate immune responses

TH2

Back 32

Help AB resposes

Review: TH1

Hint 32

Help Cell-mediated response

Front 33

T lymphocytes

Regulate immune responses

TH1

TH2

______

Back 33

Treg

Function

Hint 33

Suppress immune response

Front 34

Treg

Function

Back 34

Suppress immune response

Function of TH2

Hint 34

Help Ab responses

Front 35

NK cells

Lymphocytes?

Back 35

Y

Function

Hint 35

Destroy virus-infected and tumor cells

Front 36

NK cells

Function

Back 36

Destroy virus-infected and tumor cells

Same as?

Hint 36

CTL

Front 37

M and DC cells

Full name

Back 37

Macrophages and Dendritic Cells

How many functions?

Hint 37

2

Front 38

M and DC cells

How many functions?

Back 38

2

List

Hint 38

Phagocytosis and killing of foreign material

AP to T cells in humoral and cell-mediated immune response

Front 39

M and DC cells

2 Functions

Back 39

Phagocytosis and killing of foreign material

AP to T cells in humoral and cell-mediated immune response

Front 40

PMN

Full name

Back 40

Polymorphonuclear cells

How many?

Hint 40

3

Front 41

PMN

How many?

Back 41

4

List

Hint 41

Neutrophils

Eosinophils

Basophils and Mast cells

Front 42

PMN

________________

Eosinophils

Basophils and Mast cells

Back 42

Neutrophils

Major role in?

Hint 42

Innate defenses and inflammation

Front 43

Neutrophils

Major role in?

Back 43

Innate defenses and inflammation

Function of neutrohpils

Hint 43

Phagocytosis and killing of foreign Ag

Front 44

Neutrophils

Function

Back 44

Phagocytosis and killing of foreign Ag

Neutrohils play a major role in?

Hint 44

Innate defenses and inflammation

Front 45

PMN

Neutrohils

___________

Basophils and Mast cells

Back 45

Eosinophils

Major role in?

Hint 45

Parasitic infections

Allergic reactions

Front 46

Eosinophils

Major role in?

Back 46

Parasitic infections

Allergic reactions

Functions of eosinophils

Hint 46

Phagocytosis and killing

Front 47

Eosinophils

Functions

Back 47

Phagocytosis and killing

Major role of eosinophils

Hint 47

Parasitic infections

Front 48

PMN

Neutrophils

Eosinophils

_______________

Back 48

Basophils and mast cells

Major role in?

Hint 48

Allergic rxns

Front 49

Basophils and mast cells

Major role in?

Back 49

Allergic rxns

Front 50

Location of isotopes on Ig

Back 50

Some (1) in CL, meaning

Most (3) in CH, meaning

Hint 50

Constant light chain

Notes: 1/2

Constant Heavy

Notes: 1/2

Front 51

Location of allotypes on Ig

Back 51

Some (1) in CL

Some (3) in CH

Front 52

Location of idiotypes

Back 52

All are in VL and VH

Distribution?

Hint 52

VL: 2

VH: 3

Front 53

Idiotypes are found in CL?

Back 53

N

Where they are found?

Hint 53

VL

VH

Front 54

Idiotypes are found on CH?

Back 54

N

Where they are found?

Hint 54

VL

VH

Front 55

Idiotypes are found in VL?

Back 55

Y

They are found on CL?

Hint 55

N

Front 56

Idiotypes are found on VH?

Back 56

Y

They are found on CH?

Hint 56

N

Front 57

Primary vs. secondary antibody responses

Similarities

Back 57

First: IgM

Second: IgG

HIgher total Ab titers?

Hint 57

Secondary

Front 58

Primary vs. secondary Ab responses

differences

Back 58

Secondary

Shorter Lag

Higher IgG titers

Persistence of IgG over time

Front 59

Primary vs. secondary Ab responses

Lag?

Back 59

secondary is Shorter

IgG titers

Hint 59

Higher

Front 60

Primary vs. secondary Ab

IgG titers

Back 60

Secondary is higher

Front 61

Primary vs. secondary Ab

Persistence of IgG over time

Back 61

Secondary