Response To Cheat Sheet For Midterm Exam

Front 1

Define Pharmacokinetics

Back 1

What the body does to the drug:

• Absorption
• Distribution
• Metabolism
• Elimination

Front 2

Define Pharmacodynamics

Back 2

What the drug does to the body

• agonist ("mimetic")
• antagonist ("lytic")

Front 3

List all of the enteral drug routes (3)

Back 3

1. oral
2. sublingual
3. rectal

Front 4

List all of the parenteral drug routes (7)

Back 4

1. IV
2. IO
3. ETT
4. Inhalation
5. IM
6. Transdermal
7. Subcutaneous

Front 5

List all of the drug routes (enteral and parenteral) from fastest to slowest

Back 5

1. IV / IO
2. ETT
3. Inhalation
4. Rectal
5. Sublingual
6. IM
7. Transdermal
8. SQ
9. Oral

Front 6

What are agonists?

Back 6

• drugs that elicit a physiological response
• lock and key
• have both affinity and efficacy

Front 7

What are antagonists?

Back 7

• drugs that counteract a physiological response
• false substrates

Front 8

Name the two divisions of the autonomic nervous system?

Back 8

Sympathetic, parasympathetic

Front 9

What receptors are associated with the sympathetic nervous system?

Back 9

adrenergic

Front 10

What receptors are associated with the parasympathetic nervous system?

Back 10

cholinergic

Front 11

What are the two types of adrenergic receptors?

Back 11

alpha and beta

Front 12

What is the main adrenergic neurotransmitter?

Back 12

epinephrine

Front 13

What are the other neurotransmitters?

Back 13

norepinephrine, dopamine

Front 14

What are the two divisions of alpha and beta receptors?

Back 14

alpha 1, alpha 2

beta 1, beta 2

Front 15

Which receptors are presynaptic?

Back 15

alpha 2

Front 16

What is one other type of receptor in the adrenergic ns?

Back 16

dopaminergic

Front 17

What are the two types of cholinergic receptors?

Back 17

Muscarinic, Nicotinic

Front 18

What is the main neurotransmitter for these?

Back 18

acetylcholine

Front 19

What are the six rights of drug administration?

Back 19

1. Rt. Patient
2. Rt. Drug
3. Rt. Dose
4. Rt. Time
5. Rt. route
6. Rt. to know

Front 20

What does a sympathomimetic do?

Back 20

Stimulates the sympathetic nervous system

Front 21

What does a sympatholytic do?

Back 21

blocks the sympathetic nervous system

Front 22

What does a parasympathomimetic do?

Back 22

stimulates the parasympathetic nervous system

Front 23

What does a parasympatholytic do?

Back 23

blocks the parasympathetic nervous system

Front 24

Give an example of a parasympathomimetic

Back 24

pilocarpine (used in glaucoma, reduces eye pressure)

Front 25

Give an example of a parasympatholytic

Back 25

atropine (given during symptomatic bradycardia, blocks the SA node parasympathetic drive, lets the sympathetic NS take over)

also given in organophosphate poisining

Front 26

Give an example of a sympathomimetic

Back 26

epinephrine

Front 27

Give an example of a sympatholytic

Back 27

clonidine (blood pressure medication, blocks sympathetic tone and keeps vessels dilated, keeps BP down)

Front 28

Where does biotransformation primarily occur?

Back 28

liver

Front 29

where does elimination occurr?

Back 29

kidneys, lungs, sweat, feces, breast milk, metabolized in the body

Front 30

What is a mnemonic for Pharmacokinetics?

Back 30

ADME:

• Absorption
• Distribution
• Metabolism
• Elimination

Front 31

Where are Alpha 1 and Alpha 2 receptor sites?

Back 31

kidney, GI tract

Front 32

Where are Beta 1 receptor sites?

Back 32

heart

Front 33

Where are beta 2 receptor sites?

Back 33

lungs / skeletal muscle

Front 34

Where are dopaminergic receptor sites

Back 34

pulmonary artery, atria, kidneys

Front 35

Name examples of specific B1 blockers

Back 35

bisoprolol until metoprolol (after "m" they become unspecific (B1/B2)