Respiratory 2

Front 1

This prophylactic drug inhibits histamine from being released by working on the mast cell

Back 1

Cromolyn (only Mast Cell Stabilizer)

Front 2

If someone has an allergic reaction, Cromylin (a Mast Cell stabilizer) won't work right away. T or F

Back 2

True. Once histamine is released, it sits on H1 receptor. Once it comes off, it's metabolized by the body in approx. 3 days.

Front 3

Drugs can be used prophylactically for seasonal allergies.

Back 3

True

Front 4

Antihistamines work by blocking the______ receptor. May get partial relief w/ antihistamines due to:_______

Back 4

1. H1 receptor

(3 days to work because receptor is already occupied)

Anticholinergic affect (ACh receptor gets blocked)

Front 5

Won't get full antihistamine, anti-allergy affect, but some anticholinergic relief esp. with nasal allergies.

Back 5

True

Front 6

When the H1 receptors are blocked by antihistamines, the following BLOCKAGES occurs:

1. vasodilation of capillaries

2. itch on nerve endings

3. bronchoconstriction of bronchial smooth muscles.

Back 6

(opposite when H1 STIMULATES the receptors)

Front 7

What are the side effects of antihistamines?

Back 7

1. all have sedating properties
Diphenhydramine (Benadryl) is the most sedating.

2. Anticholinergic

Front 8

T or F, therapeutic use of antihistamines include:

1. Exudative Allergies (drainage, runny nose)

2. Allergic Dermititis (hives, urticaria/eyes)

3. Pruritis, or itching

Back 8

True

Front 9

Diphenhydramine (Benadryl) & Cetirizine (Zyrtec) are highly sedating antihistamines.

Back 9

True

Front 10

(Dimetane) & (Chlor-Trimeton) are less sedating antihistamines than Benadryl & Zyrtec

Back 10

True

Front 11

LONG acting antihistamines with a lower incidence of drowsiness:

(Allegra) & (Claritin)

Back 11

True

Front 12

Aminophylline & Theophylline (Theodur) are

Back 12

Theophyllines (The/oph/llines)

(treat asthma)

Front 13

The following effects describe:

1. Diuretic effect
2. Bronchodilation
3. Tachychardic at high doses
4. Seizures at high doses

WHICH?
A. Leukotriene Antagonists
B. Theophyllins
C. Adrenergic Bronchodialators

Back 13

Theopyllines

Front 14

Monitor patient when on Theophyllines--Two early signs of toxicity:

Back 14

1. Seizures
2. Increased heart rate (tachycardic)

Front 15

Category of asthma drugs that can induce seizures or Tachycardia at high doses

Back 15

Theophylines

Aminophylline & Theophylline

Front 16

Zafirlukast & Montelukast are what kinds of drugs?

Back 16

LEUKOtriene Receptor Antagonists

(relaxes bronchial smooth muscle)

ZafirLUKAST
& MonteLEUKAST

Front 17

Adrenergic drugs like:

Albuterol & Epinephrine

stimulates BETA 2 receptors

Back 17

(shouldn't overuse inhalers or could get chest pain)

Front 18

What is the best way to avoid spillover to Beta 1 (the heart)?

Bronchodialator with the least probability of Beta 1 spillover:

Back 18

Inhaler (for Beta 2 property of bronchodilation)

Albuterol

Front 19

Best route of administration for corticosteroids so it doesn't go systemic?

Back 19

Inhaler.

Wash out mouth (prone to thrush fungal infection)

Front 20

When given corticosteroids NASALLY, what are you treating?

Back 20

Allergic rhinitis (allergies, inflammation, runny nose)

Front 21

"Mast Cell Stabilizer"

1. Co-trimoxisole
2. Acetylcysteine
3. Cromolyn
4. Aminophylline

Back 21

Cromolyn

Front 22

Potassium Iodide (SSKI) is a

1. Antihistamines
2. Expectorant
3. Adrenergic Bronchodilator

Back 22

Expectorants

(controversial effectiveness) would have to drink 4 oz bottle every day & drink H20

Front 23

Robutussin & SSKI are _______that stimulate "production & viscosity" of mucous:

1. Antihistamines
2. Mucolytics
3. Expectorants

Back 23

Expectorants

Front 24

Antidote for Acetaminophine (Tylenol) overdose. It also protects kidneys from toxic dyes:

1. Robitussin
2. Fluticasone (Flovent)
3. Acetylcysteine (Mucomyst)

Back 24

Acetylcysteine (Mucomyst)

Administered via respiratory therapy (nebulizer)

Front 25

Parietal cells in the stomach release acid & intrinsic factors when _______is activated by the H2 receptor.

Back 25

Histamine

Front 26

This drug inhibits histamine prophylactically by working on the mast cell:

1. Cyproheptadine (Periactin)
2. Cromolyn
3. Albuterol

Back 26

Cromolyn

Front 27

Acetylcysteine (Mucomyst) protects kidneys from toxic dyes.

Back 27

True

(Also, a mucolytic agent)

Front 28

If given the following corticosteroids, we might be treating, what?

(Qvar), (Pulmicort), (Aerobid), (Flovent)

Back 28

Allergic Rhinitis

(allergies, inflammation, runny nose)

Front 29

Less chance of Beta 1 spillover with this Bronchodilator:

1. Metaproterenol
2. Albuterol
3. Terbutaline

Back 29

Albuterol

Front 30

Parietal cells in the stomach release:_______when histamine is activated. (H2 effect)

Back 30

acid & intrinsic factors

Front 31

Aminophylline & Theophylline treat:

1. Asthma
2. Ulcers
3. Urinary Tract

Back 31

Asthma (Bronchodialators)

Front 32

H2 Blockers (zantac, tagamet & pepcid) have a direct effect on parietal cells in the stomach by changing acid production.

(Benadryl, Zyrtec, Allegra & act on H1 Receptors during ALLERGIC reactions)

Back 32

True