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3 Cards in this Set

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  • Back
What percentage of pregnancies spontaneously abort? of those, what percent have a chromosome abnormality?
15% of recognized pregnancies spontaneously abort

50% chromosomally abnormal (mostly 1st trimester)

The math works out to ~1 in 13 conceptions.
Most common chromosome abnormalities in 1st trimester abortions?
45, X (Turner syndrome)
Trisomy 16
Triploidy
After 2 or more unexplained pregnancy losses...what should you start thinking about?
After 2 or more unexplained pregnancy losses, there is a high chance of a chromosome abnormality (usually balanced translocation) is ~1 in 20

think about cytogenetics