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7 Cards in this Set

  • Front
  • Back

Parts

The proximal renal tubule, loop of Henle, distal renal
tubule and collecting ducts

Func of ?

are responsible for reabsorp­
tion of water, electrolytes and other solutes, as well
as regulating acid–base balance, calcium metabolism,


rbc prd

Conversion

They also play a key
role in regulating calcium homeostasis by converting
25­hydroxyvitamin D to the active metabolite 1,25­
dihydroxyvitamin D (p. 1126). Failure of this process
contributes to the pathogenesis of hypocalcaemia and
bone disease which occurs in chronic kidney disease

Erythropoietin which cells?


loc?

Fibroblast­like cells that lie in the intersti­tium of the renal cortex are responsible for production of erythropoietin, . .

func?

which in turn is required for produc­
tion of red blood cells

reg of erythpoitin secr?

Erythropoietin synthesis is
regulated by oxygen tension; anaemia and hypoxia
increase production, whereas polycythaemia and hyper­oxia inhibit it

why anaemia in CKD?

Failure of erythropoietin production
plays an important role in the pathogenesis of anaemia
in CKD.