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7 Cards in this Set
- Front
- Back
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Mannitol
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Osmotic Diurectic that increases urine
USE: Shock, drug OD, decrease intracranial and ocular pressure DONT USE WITH CHF acts in PCT |
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Acetazolamide
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Carbonic Anhydrase inhibitor
Causes NaHCO3 diuresis and reduces total HCO3 stores USE: Glaucoma, urinary alkalinization, metabolic alkalosis, altitude sickness ACIDazolamide causes ACIDosis Acts in PCT |
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Furosemide
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Sulfonamide loop diuretic
Inhibits Na/K/2 Cl cotransporter in the thick accending limb Prevents concentration of urine and also leads to Ca excretion USE: Edematous states (CHF, cirhossis, nephrotic) HTN, and hypercalcemia TOXIC: OH DANG! -ototoxic, hypokalemia, dehydration, allergy, nephritis, gout |
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Ethacrynic Acid
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Not a sulfonamide but clinically similar to Furosemide
USE: for diuresis in patients allergic to sulfa drugs |
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Hydrochlorothiazide
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Thiazide Diuretic
Inhibits NaCl reabsorption in the distal tubule also decreases Calcium excretion USE: HTN, CHF, nephrogenic Diabetes Insipidus Toxic: Hyper GLUC hypergycemia, hyperlipidemia, hyperuremia, hypercalcemia |
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K Sparing Diuretics
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Spironolactone, triamterene, Amiloride- The K+ STAys
Spironolactone is a competitive aldosterone receptor antagonist in the cortical collecting tubule USE: Hyperaldosteronism, K+ depletion, CHF TOXIC: hyperkalemia and spironolactone can cause gynecomastia and anti androgen effects |
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ACE Inhibitor
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Captopril, enalapril, lisinopril
Inhiibits ACE--> reduces AT2 and prevents inactivation of bradykinin a potent vasodilator USE: HTN, CHF, diabetic renal disease TOXIC: cough, angiedema, proteinuria, taste change, hypotension, pregnacy problems, Rash, increased renin, low AT 2 CAPTOPRIL |
