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22 Cards in this Set
- Front
- Back
How do tetracyclines and corticosteroids cause pseudorenal failure?
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They increase protein catabolism leading to an increase in serum creatinine.
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Which drugs cause competitive inhibition of creatinine at the proximale tubule?
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Trimethoprim, Pyrimethamine or cimetidine
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What are the causes of hemodinamically mediated renal failure?
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Reduced glomerular capillary hydrostatic pressure ?<BR>Inhibition of prostaglandin-dependent renal blood flow<BR>Non-specific renal vasoconstriction<BR>Increased vascular permeability<BR>Increase in colloid oncotic pressure and blood viscoscity
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How do cephalosporine and furosemide cause pseudo renal failure?
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They interfere with the enzymatic measurement of serum creatinine
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What drugs cause reduced capilary hydrostatic pressure
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ACE and ARBs
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How do NSAIDS cause renal failure?
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Inhibition of prostaglandin dependent renal blood flow
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_______causes a transient decrease in CrCl and may cause ARF in the elderly. In combo with ________ ARF may occur in normal patients
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Triamtrene and NSAIDS
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_________renduces blood flow 10-20% in hypertensive patients
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Propanolol
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What drugs cause vasoconstriction and preglomerular arteriolar injury via decreased prostacyclin synthesis, decreased NO or increased thromboxanes synthesis?
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Cyclosporine, Tacrolymus
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________causes vascular permeability by __________secondary to release of ____________
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OKT3, capillary leak,cytokines
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Name the two drugs that cause an increase in oncotic pressure and blood viscocity
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Dextran 40 and Erythropeotin
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What two drugs cause systemic polyarteritis nodosa
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Meth, and penicillin and sulfonamide
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What do oral contraceptives, cyclosporine, mitomycin, cisplatin and quinine have in common
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They cause thrombotic micro angiopathy
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What drugs cause glomerular toxicities with minimal change to nephrotic syndrom
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NSAIDS, ampicillin, rifampin, phenytoin, lithium
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Focal segmental glomerulosclerosis syndrom is caused by?
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Heroin
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Gold and peniicilamine cause
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Membranous nephropathy
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Hydralazine causes
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Membranoprolipherative glomerulonephritis
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Active tubular necrosis is caused by
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A.G. Radio contrast dye, Amphotericin B
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Chronic interstitial nephritis is caused by
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cyclosporine and lithium
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Papillary necrosis
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phenacitin, aspirin, caffeine
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Acyclovir, indinavir and forscanet are involved in ________ a forn of ________
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renal tubular obstruction, obstructive nepropathy
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Succinylcholine
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Cholinolytique d'action directe:
- Jonction neuro-musculaire - Paralysie musculaire -empêche la transmission du NT au récepteur |