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22 Cards in this Set

  • Front
  • Back
How do tetracyclines and corticosteroids cause pseudorenal failure?
They increase protein catabolism leading to an increase in serum creatinine.
Which drugs cause competitive inhibition of creatinine at the proximale tubule?
Trimethoprim, Pyrimethamine or cimetidine
What are the causes of hemodinamically mediated renal failure?
Reduced glomerular capillary hydrostatic pressure ?<BR>Inhibition of prostaglandin-dependent renal blood flow<BR>Non-specific renal vasoconstriction<BR>Increased vascular permeability<BR>Increase in colloid oncotic pressure and blood viscoscity
How do cephalosporine and furosemide cause pseudo renal failure?
They interfere with the enzymatic measurement of serum creatinine
What drugs cause reduced capilary hydrostatic pressure
ACE and ARBs
How do NSAIDS cause renal failure?
Inhibition of prostaglandin dependent renal blood flow
_______causes a transient decrease in CrCl and may cause ARF in the elderly. In combo with ________ ARF may occur in normal patients
Triamtrene and NSAIDS
_________renduces blood flow 10-20% in hypertensive patients
Propanolol
What drugs cause vasoconstriction and preglomerular arteriolar injury via decreased prostacyclin synthesis, decreased NO or increased thromboxanes synthesis?
Cyclosporine, Tacrolymus
________causes vascular permeability by __________secondary to release of ____________
OKT3, capillary leak,cytokines
Name the two drugs that cause an increase in oncotic pressure and blood viscocity
Dextran 40 and Erythropeotin
What two drugs cause systemic polyarteritis nodosa
Meth, and penicillin and sulfonamide
What do oral contraceptives, cyclosporine, mitomycin, cisplatin and quinine have in common
They cause thrombotic micro angiopathy
What drugs cause glomerular toxicities with minimal change to nephrotic syndrom
NSAIDS, ampicillin, rifampin, phenytoin, lithium
Focal segmental glomerulosclerosis syndrom is caused by?
Heroin
Gold and peniicilamine cause
Membranous nephropathy
Hydralazine causes
Membranoprolipherative glomerulonephritis
Active tubular necrosis is caused by
A.G. Radio contrast dye, Amphotericin B
Chronic interstitial nephritis is caused by
cyclosporine and lithium
Papillary necrosis
phenacitin, aspirin, caffeine
Acyclovir, indinavir and forscanet are involved in ________ a forn of ________
renal tubular obstruction, obstructive nepropathy
Succinylcholine
Cholinolytique d'action directe:
- Jonction neuro-musculaire
- Paralysie musculaire
-empêche la transmission du NT au récepteur