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41 Cards in this Set

  • Front
  • Back

Female reproductive cycle averages how long? Consist of how many cycles?

28 days; consists of two cycles

Two cycles involved with female reproduction

Ovarian (maturation of oocyte)


Menstrual (prep endometrium for implantation)

Controlled by gonadotropin releasing hormone from hypothalamus

Hormonal regulation

____ stimulates the release of FSH and LH from anterior pituitary.

GNRH

____ initiates follicular growth and secretion of estrogens

FSH

___ Stimulates further development of the follicle, full secretion of estrogens, ovulation, development of the corpus Luteum, and stimulates production of hormones

LH

How many estrogens? # of significant?

6, 3 significant

Promotes development and maintenance of female reproductive structures, secondary sexual characteristics, and breast development

Estrogen

Estrogen increases? Lowers? And inhibits?

Increases protein anabolism, lowers blood cholesterol, and inhibits release of GNRH, FSH, & LH

Secreted by corpus luteum

Progesterone

Functions of progesterone?

Acts synergistically with estrogen for endometrial development and helps maintain pregnancy

Progesterone inhibits what?

Release of GNRH & LH

Released by corpus luteum; released by placenta

Relaxin

Functions of relaxin

Relaxes uterus, improving chances of implantation; increases flexibility of public symphysis at end of pregnancy

Secreted by growing follicle and corpus luteum

Inhibin

Inhibin inhibits secretion of what?

FSH

What happens at beginning of menstrual cycle?

Several follicles begin to mature into secondary follicles; GNRH and FSH are high; may take months

Endometrial lining is shed due to lack of progesterone; how much is lost?

Menstrual flow; 50-150 ml of blood, fluid, and tissue

Between menstruation and ovulation

Pre ovulatory phase

What happens during pre ovulatory phase?

Follicles continue to grow under influence of FSH; about day 6 one follicle outgrows others; LH levels begin to rise at end of phase

About day 6 what happens?

Dominant follicle secretes estrogen and inhibin, FSH levels decrease, other follicles undergo atresia, and endometrial lining thickens

Occurs generally on day 14

Ovulation

What causes ovulation?

High levels of LH caused by high levels of estrogen

Release of secondary oocyte when?

9 hrs after LH spike

Last approx 14 days; LH stimulates ruptured follicle to become corpus luteum

Post ovulatory phase

Corpus luteum secretes what during post ovulatory phase?

Progesterone and some estrogens, relaxin, and inhibin

During pre ovulation ___ and ___ stimulate growth of endometrium

Estrogen and progesterone

Wall thickest when?

About 1 week after ovulation

If oocyte not fertilized, corpus luteum survives how long?

About 2 weeks

If oocyte not fertilized what happens?

Progesterone and estrogen levels decrease, levels of GNRH and FSH begin to rise

If fertilization occurs what happens?

Embryo implants to endometrial lining/ produces human chorionic gonadotropin, HCG stimulates growth of corpus luteum, corpus luteum continues to secrete hormones

Occurs w/in a day of ovulation in Fallopian tube

Fertilization

Sperm make trip in how long?

30-120 mins

Secondary oocyte covered by what?

Corona radiata (granules cells, protective layer)

Sperm must digest through what?

Acrosome

Intact sperm contacts zona pellucidum (digestion)

Oocyte activation

During fusion of oocyte and sperm what happens?

Depolarization of oocyte (-Na+) & (ca+2)


Compution of meiosis II (ovum)


Harding of zona pellucidum (pollyspermy)

Formation of pronuclei and spindle called what? Happens when?

Amphimixis (first cleavage) 30 hrs after

Pre embryo continues to divide and moves through Fallopian tube

Blastocyst formation

Pre embryo arrives at uterus when?

Day 4 (known as morula)

Blastocyst formed when? Characteristics?

Day 6; hollow, trophoblast, blastoceal, inner cell mass