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126 Cards in this Set

  • Front
  • Back
steroid acne is described as...?
monomorphous red papules with NO open/closed comedones.
Tx for breastfeeding jaundice
mild/moderate - continue breastfeeding

severe/high bili - stop for 24 hrs then continue
Neonatal sepsis trick.

Looks alot like jaundice + fever/hypothermia.
ok
When is IV pyelography indicated?
diagnose renal calculi, GU neoplasm, papillary necrosis.
Oliguria in pt with no renal disease is...?
< 400 cc per day
What is the most important step of management in rib fracture? Why?
Pain control to maintain ventilation. Severe pain is the cause of hypoventilation.
Undiagnosed pleural effusion with or without suspicion of diagnosis, is diagnosed with...?

unless 1 exception.
thoracentesis.

clearcut CHF.
Name 3 tests for infertility due to aging in women.

Random fact: 20% women runs out of ovaries at age 35.
1) clomiphene challenge
2) early FSH level
3) inhibin B level.
Target limit of HbA1c is...?

Normal HbA1c is...?
<7% by studies. this is diabetic goal.

<6% is what normal ppl have.
tx of small cell cancer is mainly chemo. remember it can also cause SIADH.
ok
Tricks of Diabetic neuropathy

If UMN signs are mentions, consider spinal compression and get MRI. DM neuropathy is primarily LMN defect. Motor defects are very late in DM's.
UMN include babinski, hyper-reflexia.
Some key statistics numbers.
RR = 1 > 1 < 1 means...?
p<0.05 means what confidence interval?
p<0.01 means what confidence?
RR > 1 = positive association. = 1 means control and trial group is the same.
95%
99%
Cellulitis Facts
1) they have systemic signs like fever chills etc.
2) What does fungus have to do with cellulitis??
3) Tx
1) ok
2) fungus predisposes to cellulitis, esp for recurrent ones.
3) IV nafcillin or cefazolin for cellulitis w/ systemic signs
4) Oral dicloxacillin for cellulitis w/o systemic signs.
Extra-renal complications of AutoDom polycystic kidney diseases include...?

PKD has PAINLESS bilateral palpable ab mass! usually a-sx with HTN.

Tx
cerebral aneurysm
hepatic/pancreatic cysts
valvular defects
colon diverticula

ACEi is preferred for HTN. surgery if progressed that far.
Klinefelter XXY vs Fragile X CGG-3peat.

what's the diff?
XXY think of girly guy with small testes, moobs, etc

Fragile X think big testes, lax joints, long face, retard.
adenosine is not useful in ventricular tachy. it is for SVT.
k
Prostate causing urinary sx in elderly is a given. what is the next step before giving meds?
U/S to assess hydronephrosis.
chronic cougher with obvious cause such as GERD, smoker, postnasal drip should start with first gen anti-H2 (chlorphreniramine) or anti-H2 + decongestants.
no inhaled steroids somehow??? wtf is this shyt.
Some fkin bullshyt piece of crap about diarrhea.

Traveler. Any length of time (even up to 4 wks). Diarrhea. Prescribed Abx does not help (did not prescribe metronidazole).

Mechansim?
Giardia

adhesion and malabsorption.
Bronchoalveolar lavage takes samples

it is indicated for?
suspicions of malignancy or opportunistic infxn. Not very useful for everything else.
Golf ball feel under the skin of a lesion

-wtf does this mean?
lipoma!
Trichomonas... pt and partner or just pt? oral vs topical abx?
oral metronidazole for both to prevent recurrences.
Thalassemia keywords.

Look for target cells on smears! B-thalassemia is very similar to Fe deficiency but the MCV is sosososo low whereas Fe def may be moderately low.
ok
In any fkin case of fractures, look for signs of vascular compromise such as bruits or coldness etc. What is your next step if you find these signs?
angiogram!
CLL is a pretty good disease of older population. Apparently, it is usually incidentally found. CLL is benign unless severe.

What is the one biggest clue in peripheral smear that it is CLL?
smudge cells = fragile cells that smudges out during preparation process.

The one biggest poor prognostic factor is thrombocytopenia.
Esophageal cancer diagnostic steps?
Barium swallow followed by endoscopy

if negative but still suspect, try PET scan.
Tricks

-pt comes in with terrible wbc differential concerning for bone marrow malignancy. You consider doing bone marrow biopsy. However, he also has symptomatic hypercalcemia. What is the best next step?
treat hyperca first w/ IVF.

Asx or mild hyperCa (<12) = no tx, avoid dehydrate.
Severe >14 HyperCa: acutely IVF, chronic bisphosphonate.
Diaphragmatic Injury
-common after accidents.
-xray shows opacity of left lower lobes (which is actually the hernia)
-which side is more common?
left side more common since right side is protected by liver.
Physician has obligation to court order parents to comply with certain treatments that will do much more good than harm. Also non-treatment has high mortality risk.
dam
what etiology of hypercalcemia is treated with steroids?
sarcodosis and lymphoma.
This is something you just gotta memorize

Medulloblastoma in kids. #2 MCC posterior fossa tumor (after cerebellar astrocytoma). Most commonly affects....which area and what are the sx?
cerebellar vermis

sx = all typical mass effect signs + gait, trunk dystaxia, nystagmus.
Primary Hyperaldosterone... odd facts.

-Pt are usually asx and found to have familial HTN.
-Pt are very prone to hypoK+ after starting HCTZ!
if this happens, think hyperaldo and measure renin-aldo ratio!
Prolactinoma (pituitary adenoma) are always treated with DA agonists first.

Bromocriptine and Cabergoline (remember this trick).
d
You got this right, but were a little hesitant. Just a reminder.

Conduct Disorder (<18yo) = Antisocial Personality (18+yo)
k
4 Indications of PCN ppx during delivery given that GBS status is unknown.
1) delivery < 37wks.
2) membrane rupture > 18hrs ago.
3) GBS bacteruria at anytime during the pregnancy.
4) Prior hx of GBS sepsis infant after preg.
Finally you get to learn Fanconi's Anemia!
>>X-recessive onset anytime before age 16!
*Aplastic anemia (maybe pancytopenia)!
*hypopigmented, abn thumb bones!
*middle ear abnormalities!
Tx? Mechanism of Fanconi?
Tx is stem cell transplant

Mechanism of Fanconi anemia is some chromosomal break.
Oddly enough, thymoma has pure red cell aplasia.
not sure why. dont feel like finding out.
What are most of the drugs that can potentiate warfarin?

what diet has plenty of vitamin K to decrease warfarin ASE?
acetaminophen
NSAID
amiodarone
abx

--veges!
HSV encephalitis. As if clinical or CSF diagnosis is not enough, PCR is the gold diagnosis.
ok
Xanthelasma, as you know, is well associated w/ XOL. but guess what, it's also associated with PBC! that female autoimmune biliary cirrhosis with the positive AMA
lel
Tx of claudication or PAD.

3 steps of management!
1) low dose ASA and statin.
2) supervised exercise program.
3) if 1,2 fails, surgery.
Another trick of Kawasaki.

If you don't have strawberry tongue but has fissures of the lip, it still counts as mucositis!
ok
Pancreatic cancer
1) what are the few associated events that causes you to think this diagnosis? among the other staple sx.
2) HOw do you diagnose this in terms of presentation with jaundice vs non-jaundice?
3) What can you say about the tumor location with respect to abv question?
1) recent onset DM, migratory thrombophlebitis.
2) U/S if jaundiced. CT if not
3) Jaundiced = tumor at head of pancreas. Not jaundiced = tumor at body or tail of pancreas.
Open angle glaucoma opthal exam

just remember these keywords.

Tx
cupping of optic disk

slow loss of peripheral vision "tunneling"

Tx: PGE (lanoprost), Timolol, physostigmine, etc.
More Associations
1) Aortic Regurg = widened pulse (pt feels like palpitation at times).
2) Aortic Stenosis = weak pulse
most common cause of aortic regurg is rheumatic fever worldwide. In USA, it is aortic root dilation and bicuspid aortic valve.
YOu seem to be pretty ret@rded when it comes to calcium. So here goes again.

ANY Fkin ab defect can cause malasorption hence hypo-Vit D hence low Ca. Body reacts by secondary hyperPTH restoring normal Ca but low P. Bone is hurt. ok
fk you.
Selegiline or however you spell this shyt is MAOi that's all you need to remember.
cuz fkin q bank always use the most obscure drug of a class.
Another fkin obscure drug.

Trihexyphenidyl is....? what is it for...? what other are in its class?
anticholinergic, for parkinson, like benztropin.

You know what, anticholinergics can induce glaucoma. that's why you can use physostigmine to treat open glaucoma.
CXR for pneumonia
1) when to get it?
2) when is it negative despite its pneumonia?
1) everytime you suspect pneumonia! confirmatory test!
2) <24hrs of onset, dehydrate, PCP, neutropenia, or atypical pneumo.
Leprosy!!! is a chronic granulomatous disease that affects.... which 2 things???
nerves and skin! do skin biopsy for acid fast bacilli mycobacterium leprae.

you may see hypopigmented skin lesion w/ no feeling on that lesion!
ASD is asx mostly. No cyanosis.

If there is a mumur it will be where and why?
pulmonic valve due to extra load.
VSD will not have cyanosis either.

murmur is holosystolic.
ok
Just remember lead poisoning is microcytic anemia. also does renal dmg, neuro stuff. ok
ok
Fking Hyperbilirubinemia Syndromes
1) Defect in Hepatic Storage
2) Auto-recessive cause of elevated unconjugated bilirubin.
3) Dubin-Johnson is like #1 except?
4) Liver steatosis due to long long OCP use
1) no sx. nothing elevated except both direct and indirect bili.
2) this is the only one that's fatal and req phototherapy or liver transplant (crigler-najjar = crazy name = bad fate).
3) just direct bili is elevated primarily. and biopsy shows really black hepatocytes for some reason.
4) yeah ok, your gonna have elevated AST/ALT.
Renal or ureter stones.

- what is the preferred diagnostic test?
#1 is non-contrast CT of ab and pelvis.

#2 is IV pyelography (used to be favored, but not anymore due to contrast). Know that pyelography is xray with contrast. Xray in itself cannot see 15% of radiolucent stones.
Waldenstrom's Macroglobulinemia is rare chronic plasma cell neoplasm that shows spike in IgM in PCR. it invades marrow and causes anemia, thrombocytopenia and demyelinates crap.

How does it differ from MGUS or MM?
MGUS is mostly asx or have mild sx.

MM is very similar in presentation but IgA and IgG are involved instead. IgA is the heavy chain.
Complicated pregnancy matters.

If Father is Rh + and Mother is Rh -, we give anti-Rh IgG obviously at 28wk and postpartum. However, if later we find the mother to be strongly anti-Rh+, it is obvious the therapy has failed. What is the most likely reason it has failed?
Low post-partum anti-Rh+ dose.
NSAID and pregnancy

be specific
No NSAID during 3rd trimester for sure. Premature closure of PDA.
Obstructive lung disease FEV/FVC ratio

Restrictive lung disease
below 80%

>80%.
Osgood-Schlatter's Tibial Bone Dz.

It is apophysitis of patella/tibia knee region worse w/ adolescent exercise and extension of the knee!

Tx?
NSAID, stretching, less activity.
Significant H&P's to diagnosis
1) bursitis
2) tendonitis
1) pain w/ direct pressure (sleeping), maybe swelling.
2) not sure but has pain/swelling/heat after a noticeable tweak. just remember you tweaking your ankles in basketball games.
Baker's cyst occurs in popliteal fossa where inflammed synovium makes too much fluid.

Associated with which 3 conditions?
Tx?
RA
OA
cartilage tears.

Mostly, no Tx. Steroid, drainage may be done if asked.
Avascular Necrosis: Radiology

X-ray
MRI

Tx
xray will be negative in first few months

MRI is the most accurate.

Tx is mostly surgical. Non-surgical is unfavorable.
Rotator Cuff Tendinitis vs Adhesive Capsulitis
1) Rotator Tendinitis: very similar except lidocaine injection allows significant improvement in ROM. Even rotator cuff tear does not improve w/ lidocaine.

2) Adhesive is fibrosis of shoulder capsule and does not improve with lidocaine injection.
Must remember association:

Myeloproliferative Disorder (such as poly vera) causes shyt-tons of basophil production. So what you get after hot shower?
HA and extreme itch!
If no neuro sx... even if description of back pain suggest dangerous things, start with x ray first. then MRI if xray negative.
lol k.
If a young adult female has very RA-like sx plus facial rash, some renal red flags, etc...think lupus.

SLE joints differ from RA joints because?
non-deforming! less likely to have erosions.
Coffin lid shaped crystal is associated with struvites. Don't get confused when placed in same sentence as rhomboid shaped CPPD crystal!

CPPD is associated with which systemic disorder?
hyper-PTH. Recall inc Ca intake reduces gout.
Giant cell arteritis's famous complication.

Think of it this way. which system is giant cell arteritis part of? hence its complication? how do you manage it?
aortic aneurysm!

serial CXR!
Any inflammatory arthritis that resolves within 2 month should be considered viral. Hep, B19, mump, rubella, etc.
ok
Erythema nodosum dDx and next steps
1) If pt has no acute GI exacerbations...?
2) If pt has acute GI exacerbations..?
1) CXR for sarcoidosis, TB (may sub PPD), or ASO titer.
2) colonoscopy.
RA vs polymyalgia rheumatica

If sx of joint pain are mostly confined to neck, spine, hip without mentioning fingers (and swelling etc)... cross RA off the list. Tx is...?
steroids, with great success.


In RA, small joints are invovled first. large joints late in disease.
Charcot's neurogenic arthropathy is a gay one.

-imaging looks like OA but has deformities and shyt like RA. Also grossly deformed.

Cause?
repeat insult to weight bearing joint commonly associated w/ DM, and any other nerve dmg.

pain is mild.
Chronic ankylosing spondylitis results in osteoporosis and complications include easy vertebral fx

sx therefore will be severe persistent back pain out of little injuries.
k.
migratory arthritis causes include...?
gono
SLE
lyme's
rheumatic arthritis
For reasons only to trick you, those who have osteomyelitis may not have fever or elevated WBC.
fk you then
Common Question missed
> End stage cancer pt with anorexia and wt loss shoudl take which drug to improve eating?
steroids

PGE analog (megestrol or medroxyprogesterone).
Wiskott-Aldrich =
recurrent pneumonia, eczema, thrombocytopenia from impaired platelet production.
polycythemia requires hematocrit > 65%
ok
Pt with evidence of pulm embolisms should be given anti-coags first then diagnostic tests.

Pt w/ low suspicion of DVT should be d-dimer test first but higher suspicion should be given compression ultrasound first. So for DVT, diagnostics first.
ok
Management for SIADH tumor cells is resect tumor if possible. Otherwise if decided to wait, how do you stop the SIADH?
fluid restriction. not DDAVP.
Hairy cell leukemia specials.
1) Bone marrow shows? successful or no?
2) cytochemical shows?
3) prog
4) tx
1) Dry tap, often unsuccessful due to fibrosis.
2) TRAP stain (tartaric resistant acid phosphatase).
3) Prog = most benign leukemia
4) Tx w/ cladribine.
Hemolytic anemia + Thrombocytopenia

+/- AMS, renal failure, slight fever.

What is the likely diagnosis? What will peripheral blood smear show?
TTP = clinical diagnosis. ADAMTS13 not needed.

lots of shistocytes!
Citrates in packed red blood cell transfusions can chelate Ca and Mg much like albumin and cause paresthesias.
ok
Glucagonoma
- presentation
- easily mistakened for?
-mild DM, hyperglycemia, necrotic migratory erythema, watery diarrhea, anemia, wt loss!
-DM, but is quite easily treated w/ oral agents and diet changes unlike real DM.
Small cell carcinoma = which sx?

Squamous cell carcinoma = which sx?
ACTH and SIADH.

PTHrp only
women with multiple spontaneous abortions + DVT... think think think?
lupus or APL
Leukemoid Reaction is an extreme rxn to stress or infxn maniefsts with high WBC count >50k and slightly high platelet count > 400k. BUt normal Hb.
k
Superficial Thrombophlebitis
1) associated with what?
2) presents with what?
1) occult cancers! pancreas, stomach, lungs! associated w/ smokers
2) unusual site of migratory thrombophlebitis like arms and chest.
If anemia is accompanied by reticulocytosis, then it's hemolytic anemia.
1) warm hemolytic anemia associations?
2) Tx
1) associated w/ NHL and CLL
2) prednisone, else splenectomy.
Pernicious Anemia is most common in which groups of folks?
Euros. so think other autoimmune crap.
Serous otitis media.. how do you get this crap?
HIV = big lymph nodes = compress.
INH toxicity = what types of tox?

no skin problems you dumbfk
neuro tox and hepatotox.
New onset diabetes.... name the fkin things that cause it. don't just give me one. give me at least 3!
hemochromatosis
pancreatic cancer
some other crap donno.
Trastuzumab for Her2/neu positive patients

what's ASE w/ chemo?
heart tox hence perform echo.
Normally, sickle cell pt has high reticulocyte count. But in aplastic crisis, sickle cell patients have ~1% reticulocyte count.

1% is normal though. BUt for sickle cell pt, 1% is like non-existent!
ok
acidified glycerol lysis test is for?

eosin maleimic binding test is used too.
spherocytes. i think it's part of osmotic fragility test.
In breast cancer

Her2/neu expression is considered worse prognosis BUT... can be treated with trazustunub.
kk
Tricks

Metastatic brain lesion most commonly occur where? and is solitary or multiple?

what is the prefered tx?
solitary AND multiple! it can appear as either!

gray-white junction!

best tx for solitary brain met is surgery! then radiate anything left!
Small cell carcinoma of the lung is the only one that cannot be surgically removed. Must use combo chemo!
kk
CML vs leukemoid rxn (given the labs with high high WBC with mostly bands, high platelet, and anemia).
1) difference in sx?
2) difference in lab tests?
3) what is tartrate resistant acid phosphatase?
1) CML has B-sx
2) leukemoid rxn has elevated leukocyte alklaline phosphatase (LALP) while CML has decreased LALP.

3) it's present in hairy cell leukemia dumb fk.
Pt comes in with mouth papules that blanch, random hx of nose bleeds, signs of digital clubbing (aka low O2 aka erythrocytosis aka high hematocrit).

Labs show normal WBC and platelet. what is this disorder? and why the nose bleed?
Hereditary telangiectasia (Osler Weber Rendu)

***diffuse AVM that can occur anywhere! shunting in lungs cause clubbing. AVM in nose = epistaxis = nose bleed.
Tips of lung cancer

-which cancers are central and which are peripheral? it's easier than you think! just think the two most memorable ones are central!
-which one can have cavitations and necrotic? this is easy!
-what is the only lung cancer that can have gynecomastia or galactorrhea (up PRL)?? this is tough! you haven't heard this before so it can't be the typical ones!
1) sq and small cell!
2) sq
3) large cell carcinoma
Hyposthenuria is inability to concentrate urine so results in nocturias.

Usually you see FHx of siblings with blood disorder. If you still don't get it, usually they're African American.

What's the cause?
sickle cell trait or sickle cell dz!
Breast Cancer Tips
1) Pt w/ no hx of skin disease develops breast rash unresponsive to standard therapy think...?
2) Most paget's has what type of cancer?

sx = unilateral eczematous nipple rash unresponsive to tx.
1) breast cancer! not fibroadenoma and shyt, but cancer! most likely paget's!
2) adenocarcinoma!
ITP Tx: very different approach from kids to adults!
1) Kids - when to observe vs give IVIG/steroids?
2) Adults- when?
1) Observe if only see petechiae but NO bleed yet. Tx if bleed. Even if platelet is 0, you don't treat.

2) Adults should be treated if platelet <30k! OR bleed! either one!
Put it all together!

Young Adult!
Northern European!
Anemia!
Jaundice, possible cholecystitis!
Splenomegaly!

What is the Dx and how are these things related??
Hereditary Spherocytosis (common in N. Euro).

hemolysis -> pigmented cholecystitis.
Thalassemia vs Fe deficiency again!

1) labs!

2) What does abnormal iron utilization mean?
1) thalassemia has all labs normal! RDW, ferritin, iron binding capacity.
---Fe def = RDW increased, Low serum Fe + ferritin! High others.

2) a way of describing anemia of chronic disease!
Most accurate test for lactose intolerance is ?
acid breath test after giving lactose.
FAP = familial adenomatous polyposis = how to treat?

HNPCC (hereditary nonpolyposis crap) = how?
100% cancer rate so colectomy if find (usually around 20yrs old).

--impaired DNA mismatch with high cancer risk, surgery too.
Pt with brain metastasis. Without any other info, what's the most likely origin?
Lung > breast > ? > melanoma > colon. the rest are not likely.
HIT 1 vs HIT 2

You already have a flashcard on this but this one discuss a different matter. What is the two biggest difference that determines management? Hint (timing and platelet count)
HIT 1 = first 1-4 days and platelets >100k! OBSERVE!

HIT 2 = 5-10 days after heparin and platelet usually < 100k!
DIC vs Vitamin K deficiency

Given elevated PT and PTT.
Given Platelet > 100k.
Vit K deficiency.
Surgery Preparation
1) Pt under age 35 w/o CAD Hx, what must be done?
2) Pt w/ Hx of CAD, what must be done preop?
3) Smokers
1) EKG
2) EKG + Stress test + Echo for EF!
3) PFT
Trauma And Airway
1) Facial Trauma requires?
2) No facial trauma, which type of intubation?
3) cervical spine injury?
1) crciothyrodotomy
2) orotracheal tube
3) orotracheal tube done by flexible bronchoscopy.
SIRS = 2/4 of what?
Temp <36 or >38
HR > 90
RR > 20 or pCO2 < 32.
WBC < 4k or >12k.
In which type of shock is....
1) PCWP elevated?
2) extremeties warm?
3) treated w/ fluid and pressors?
1) cardiogenic
2) spetic and neurogenic
3) all except cardiogenic. add abx for septic.
SIgns vs Ab Trauma
1) Cullen's Sign or Bruise around umbilicus
2) Bruising around flank
3) seatbelt bruise
4) Free air under diaphragm on XR
1) hemorrhagic pancreatitis or ruptured AAA
2) retroperitoneal hemorrhage
3) deceleration injury.
4) Bowel perforation
Blood at Urethral meatus + high riding prostate

next step management?
KUB + retrograde urethrogram

then foley for voiding but never before.
Bowel Ischemia next step managements!
IVF angio surgery.
Orthopedics: Fracture rules
1) Alwyas diagnosed with?
2) Closed reduction is for?
3) Open reduction + internal fixation for?
4) Open reduction for?
1) xray
2) mild fx w/o displacement, except stress fx.
3) severe fx w/ displacement.
4) skin must be closed and bones debridement in OR.
Trigger finger
1) mechanism
2) Tx
1) steonsis of tendon sheath of finger
2) steroid, else surgery.
Fat Embolism pO2 is generally around?
< 60mmHg, so management should keep pO2 > 95%.
ACL is generally tx'd with? (significant swelling)

MCL/LCL is tx?

Meniscal tx? (popping w/ flexion and extension)
all are arthroscopic repair + rehab

all dx with MRI.
surgery is indicated for AAA > ?cm
5cm
wind water walk wound wonder by POD's is in interval of 2's.

1-2 days (wind). 3-5 days (water). 5-7 days (walk). 7 days (wound). 1wk-2wks (wonder).
z