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19 Cards in this Set
- Front
- Back
Diphenhydramine
|
1st gen H1 reversible blocker
Allergy, Motion Sickness, Sleep Aid Tox: sedation, antimuscarininic, anti-α-adrenergic, antiserotinergic |
|
Dimenhydrinate
|
1st gen H1 reversible blocker
Allergy, Motion Sickness, Sleep Aid Tox: sedation, antimuscarininic, anti-α-adrenergic, antiserotinergic |
|
Chlorpheniramine
|
1st gen H1 reversible blocker
Allergy, Motion Sickness, Sleep Aid Tox: sedation, antimuscarininic, anti-α-adrenergic, antiserotinergic |
|
Loratidine
Desloratidine |
2nd gen H1 reversible blocker
Allergy Tox: far less sedating b/c of low CNS entry |
|
Fexofenadine
|
2nd gen H1 reversible blocker
Allergy Tox: far less sedating b/c of low CNS entry |
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Cetirizine
|
2nd gen H1 reversible blocker
Allergy Tox: far less sedating b/c of low CNS entry |
|
Isoproterenol
|
Nonspecifc β-agonist: bronchodilation (β2)
Asthma SE: tachycardia (β1) |
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Albuterol
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β2-agonist
Acute Asthma exacerbation |
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Salmeterol
|
β2-agonist (long acting)
Asthma prophylaxis SE: tremor, arrhythmia |
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Theophylline
|
Methylxanthine: blocks adenosine & inhibits phosphodiesterase= ↑cAMP
Asthma- narrow therapeutic index Tox: cardio, neuro Metabolized by P450 |
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Ipratropium
|
M receptor antagonist= prevents bronchoconstriction
Asthma, COPD |
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Cromolyn
|
Mast Cell Stabilizer
Asthma Prophylaxis |
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Beclomethasone
|
Corticosteroid: ↓cytokines, ↓inflammatory agents, ↓NF-KB= ↓TNFα
Chronic Asthma (1st line) |
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Prednisone
|
Corticosteroid: ↓cytokines, ↓inflammatory agents, ↓NF-KB= ↓TNFα
Chronic Asthma (1st line) |
|
Zileuton
|
5-lipoxygenase pathway inhibitor: ↓leukotrienes
Asthma |
|
Zafirlukast
Montelukast |
Leukotriene receptor antagonist
Aspirin-induced Asthma |
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Guaifenesin
|
Robitussin: removes excess sputum; does NOT suppress cough reflex
|
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N-acetylcysteine
|
Mucolytic
Cystic Fibrosis patients Antidote for acetaminophen OD |
|
Bosentan
|
Endothelin-1 receptor competitive antagonist= ↓pulmonary vascular resistance
Pulmonary Hypertension |