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19 Cards in this Set

  • Front
  • Back
Diphenhydramine
1st gen H1 reversible blocker
Allergy, Motion Sickness, Sleep Aid
Tox: sedation, antimuscarininic, anti-α-adrenergic, antiserotinergic
Dimenhydrinate
1st gen H1 reversible blocker
Allergy, Motion Sickness, Sleep Aid
Tox: sedation, antimuscarininic, anti-α-adrenergic, antiserotinergic
Chlorpheniramine
1st gen H1 reversible blocker
Allergy, Motion Sickness, Sleep Aid
Tox: sedation, antimuscarininic, anti-α-adrenergic, antiserotinergic
Loratidine
Desloratidine
2nd gen H1 reversible blocker
Allergy
Tox: far less sedating b/c of low CNS entry
Fexofenadine
2nd gen H1 reversible blocker
Allergy
Tox: far less sedating b/c of low CNS entry
Cetirizine
2nd gen H1 reversible blocker
Allergy
Tox: far less sedating b/c of low CNS entry
Isoproterenol
Nonspecifc β-agonist: bronchodilation (β2)
Asthma
SE: tachycardia (β1)
Albuterol
β2-agonist
Acute Asthma exacerbation
Salmeterol
β2-agonist (long acting)
Asthma prophylaxis
SE: tremor, arrhythmia
Theophylline
Methylxanthine: blocks adenosine & inhibits phosphodiesterase= ↑cAMP
Asthma- narrow therapeutic index

Tox: cardio, neuro

Metabolized by P450
Ipratropium
M receptor antagonist= prevents bronchoconstriction
Asthma, COPD
Cromolyn
Mast Cell Stabilizer
Asthma Prophylaxis
Beclomethasone
Corticosteroid: ↓cytokines, ↓inflammatory agents, ↓NF-KB= ↓TNFα
Chronic Asthma (1st line)
Prednisone
Corticosteroid: ↓cytokines, ↓inflammatory agents, ↓NF-KB= ↓TNFα
Chronic Asthma (1st line)
Zileuton
5-lipoxygenase pathway inhibitor: ↓leukotrienes
Asthma
Zafirlukast
Montelukast
Leukotriene receptor antagonist
Aspirin-induced Asthma
Guaifenesin
Robitussin: removes excess sputum; does NOT suppress cough reflex
N-acetylcysteine
Mucolytic
Cystic Fibrosis patients

Antidote for acetaminophen OD
Bosentan
Endothelin-1 receptor competitive antagonist= ↓pulmonary vascular resistance
Pulmonary Hypertension