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13 Cards in this Set
- Front
- Back
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What is Allergic Bronchopulmonary Aspergilosis?
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is a hyper sensitivity of the lungs to fungal antigens that colonize the bronchial trees.
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Presentation of ABPA? |
Look for asthmatic patient with recurrent episodes of brown flecked sputum and transient infiltrates on chest x ray. |
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ABPA Diagnostic Testing? |
peripheral eosinophilia skin test reactivity to aspergillum antigens precipitating antibodies to aspergillus on blood test elevated serum IgE levels Pulmonary infiltrates on chest x ray
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Treatment for ABPA? |
Oral Steroids-Prednisone Itraconazole ORAL for recurrent |
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What is Cystic Fibrosis? |
is an autosomal recessive disease caused by a mutation in the genes that code for chloride channels. Leads to abnormal thick mucus in the lungs liver pancreas small intestines gu sinuses. |
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Cystic Fibrosis Presentation? |
Look for young adult with chronic lung disease -cough,sputum,hemoptysis,bronchiectasis, wheezing, and dyspnea with recurrent infection episodes. |
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What area CF gastrointestinal manifestations? |
Meconium ileus Pancreatic Insuffiency Recurrent Pancreatitis Distal Intestinal obstruction Biliary cirrhosis |
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CF GU manifestations? |
Azoospermia thick cervical mucus |
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What is most accurate test for CF? |
increased sweat chloride test |
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What increases sweat production? |
Pilocarpine increases acetylcholine which in turn increases sweat production. |
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What is the number that diagnoses in sweat chloride test? |
60meq/L |
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what is found in sputum culture of CF? |
H influenza Pseudomonas aerugenesa staph aureus Burkholderia cepacia |
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Treatment for CF? |
1. Antibiotics are routine (same as bronchiectasis) 2. rhDNASE 3. Inhaled Bronchodilator 4. Pneumoccal +influenza vaccine 5. Lung transplantation |
