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60 Cards in this Set

  • Front
  • Back
What is neuronal plasticity?
parts of the brain remodel to compensate in response to changes in environment or received inputs
what is declarative memory?
memory for general and autobiographical facts
what is nondeclarative memory?
memory for learned behaviors both explicit and implicit. AKA procedural memory
What kind of metabolic activity is thought to occur in neurons to facilitate long term learning?
Synthesis of proteins and RNA in neurons that synapse during short term learning
The limbic system: collects imputs from?
the hypothalamus (and therefore collects visceral signals from sensory cortex and brainstem), prefrontal cortex and inferior temportal association cortex
The limbic system: mediates?
emotional and instinctual responses
The limbic system: important structures include?
Amygdala, hippocampus
the amygdala is involved in?
fear, anxiety
the hippocampus is involved in?
learning, memory
T/F the basal ganglia is deep gray matter?
TRUE
important structures of the basal ganglia include?
caudate, putamen, thalamus, neurotransmitter systems, and RAS
the caudate becomes severly in atrophies in what disease?
huntington's
the putamen and caudate have a high concentration of what kind of receptors which are the target of antipsychotic drugs, causing abnormal involuntary movements?
D2 receptors
the thalamus is involved in?
sensation and pain
what are the dopamine pathways?
nigrostriatal, mesocortical, mesolimbic, tuberoinfundibular
which dopamine pathway connects the substantia nigra to caudate and putamen?
nigrostratal
which dopamine pathway connects the VTA to the prefrontal cortex?
mesocortical
which dopamine pathway connects the VTA to amygdala and hippocampus?
mesolimbic
which dopamine pathway connects arcuate nucleous of the hypothalamus to the pituitary?
tuberoinfundibular
anti-psychotics block D1 and D2 that are rich in this pathway.
what the nigrostriatal pathway?
this dopamine pathway mediates cognition and is responsible for negativism seen schizo via D1, seratonin (5-HT) receptors.
whatis the mesocortical pathway?
excess dopamin here causes hallucinations seen in schizo?
what is the mesolimbic pathway?
blockade of dopamine via antipsychotics here causes elevated prolactin?
what is the tuberoinfundibular pathway
this association region of the brain recieves input from the neocortex, limbic regions, hypothalamic regions, brainstem, and most of the rest of the brain via the thalamus.
what is the prefrontal cortex?
the prefrontal cortex is responsible for what behavior?
executive function
exmaples of executive funtion?
abstract thought, creative problem solving, temporal sequencing of behavior
what are examples of tests that assess the intactness of the prefrontal cortex?
wisconsin card sorting, Go/No-Go tasks, Trails tests
with regards to prefrontal intactness, peeps with schizoprenia may be thought of as having?
hypofrontality
with regards to prefrontal intactness, people with OCD may be considered as having?
hyperfrontality
dopamine pathways in general originate from either the ____ or the ____?
ventral tegmental area, arcuate nucleus
the norepinephrine system arises from ____ and has projections to_____?
locus ceruleus, the entire brain
the serotonin (5-HT) system arises in?
the raphe nucleus
TBI most commonly affects the?
frontal lobes
another term for long term memory is?
consolidated memory
aphasia is a disorder of?
language, NOT speech
important structures associated with language are typically localized to?
the left hemisphere in most people
broca's area is where and controls what?
posterior frontal cortex, speech production and fluency
the wernicke's area is where and does what?
posterior temportal lobe, permits understanding or interpretation of language
lesions in this area cause expressive aphasia
what is broca's area?
lesions in this area cause receptive aphasia.
what is wernicke's area?
2 diagnostic criteria for TBI?
an injury occurred and there was alteration of consciousness
this excitatory amino acid neurotransmitter is thought to causes neurodegeneration through excessive excitation.
what is glutamate?
anxiolytic drugs are ____ agonists and and increase _____ tone in the CNS.
GABA, inhibitory
90% of the population is right handed and left hemisphere dominant for?
language and praxis
right hemisphere is dominant for?
complex perceptual processing such as facial recognition
lesions of the dominant parietal lobe can result in?
language abnormalities, tactile agnosia and apraxia
lesions of the non-dominant parietal lobe can result in?
anosognosia, constructional dyspraxia, and contralateral neglect
lesions of the dominant temporal lobe can result in?
anomia and anterograde verbal amnesia
lesions of the nondominant temporal lobe can result in?
anomia for facial expressions and anterograde visiospatial amnesia
bilateral lesions of the temporal lobes can cause?
korsakoff;s amnesia and kluver-bucy syndrome
What lesion? Tactile agnosia
L parietal
What lesion? Language Abnormality
L parietal
What lesion? Contralateral neglect
R parietal
What lesion? Disinhibition and impulsivity?
Frontal lobe
What lesion? Anomia, anterograde amnesia?
L temporal
What lesion? Anomina for facial expression, (visuospatial) anterograde amnesia?
R temporal
What part of the limbic does fear and anxiety?
amygdala
What part of the limbic does learning and memory?
hippocampus
T/F attentional defecits are NOT localizable?
TRUE;
Ach neurons from the nucleus basalis of meynert project to the ________ for memory, and the _______ for attention?
Hippocampus; Cingulate gyrus