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73 Cards in this Set
- Front
- Back
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Citalopram
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SSRI
Fewest drug-drug interactions |
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Escitalopram
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SSRI
Levo-enantiomer of citalopram, possibly fewer side effects |
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Fluoxetine
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SSRI
Longest half-life, used in kids common sleep changes, elevates levels of neuroleptics |
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Fluvoxamine
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SSRI
approved for OCD nausea and vomitting common |
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Paroxetine
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SSRI
more anticholinergic effects shorts half-life = withdrawal |
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Sertraline
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SSRI
Highest risk for GI disturbances |
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Venlafaxine
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SNRI
Can increase BP |
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Desvenlafaxine
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SNRI
Can increase BP |
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Duloxetine
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SNRI
also used for neuropathic pain more dry mouth and constipation than SSRIs |
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Trazodone
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Serotonin antagonist and reuptake inhibitor
sedation, priapism |
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Amitriptyline
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TCA
usefule in chronic pain, migraines, and insomnia |
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Clomipramine
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TCA
more serotonin specific, useful in treatment of OCD |
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Doxepin
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TCA
useful in treating chronic pain (and potentially sleep aid) |
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Imipramine
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TCA
Useful in enuresis and panic disorder Has IM form |
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Amoxapine
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TetraCA
May cause EPS becuase it's a metabolite of loxapine |
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Desipramine
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TCA
More activating least sedating, least anticholinergic |
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Nortriptyline
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TCA
Least likely to cause orthostatic hypotension treats chronic pain |
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Protriptyline
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TCA
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Bupropion
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Norepinephrine/Dopamine reuptake inhibition (behavioral effects attributed to Norep)
Mild psychostimulant, increased seizure risk |
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Mirtazapine
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a2-antagonist, specific serotonin antagonist
weight gain and sedation useful side-effects |
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Isocarboxazid
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MAOI
hypertensive crisis, orthostatic hypotension, drowsiness, weight gain, sexual dysfunction, dry mouth |
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Phenelzine
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MAOI
hypertensive crisis, orthostatic hypotension, drowsiness, weight gain, sexual dysfunction, dry mouth |
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Selegiline
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MAOI
hypertensive crisis, orthostatic hypotension, drowsiness, weight gain, sexual dysfunction, dry mouth |
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Tranylcypromine
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MAOI
hypertensive crisis, orthostatic hypotension, drowsiness, weight gain, sexual dysfunction, dry mouth |
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Alprazolam
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Intermediate Acting Benzo
Onset of Action: Fast-Intermediate Causes euphoria, high abuse potential |
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Chlordiazepoxide
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Librium (10mg), benzo
Onset of Action: Fast |
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Clonazepam
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Long-Acting Benzo
Onset of Action: Intermediate |
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Clorazepate
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Tranxene (7.5mg), benzo
Onset of Action: Fast |
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Diazepam
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Long-Acting Benzo
Onset of Action: Fast |
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Estazolam
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ProSom (0.33mg), benzo
Onset of Action: Fast |
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Flurazepam
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Dalmane (30mg), benzo
Onset of Action: Intermediate |
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Halazepam
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Paxipam (20mg), benzo
Onset of Action: Intermediate |
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Lorazepam
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Intermediate Acting Benzo
Onset of Action: Intermediate Not metabolized by the liver |
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Midazolam
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Short Acting Benzo (<6hours)
Onset of Action: Intermediate Primarily used in surgical settings |
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Oxazepam
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Intermediate Acting Benzo
Onset of Action: Slow Not metabolized by the liver |
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Prazepam
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Centrax (10mg), benzo
Onset of Action: Slowest |
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Quazepam
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Doral (15mg), benzo
Onset of Action: Fast-Intermediate |
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Temazepam
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Intermediate Acting Benzo
Onset of Action: Intermediate Not metabolized by the liver |
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Triazolam
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Short Acting Benzo (<6hours)
Onset of Action: Intermediate Primarily used in surgical settings |
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Zolpidem
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Bind benzo receptor 1
Onset of Action: Fast half-life: 2-2.5 hours |
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Zaleplon
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Bind benzo receptor 1
Onset of Action: Fast-Intermediate half-life: 1 hour |
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Eszopiclone
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Bind benzo receptor 1
half-life: longest of sleep aids |
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Carbamazepine
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Mood Stabilizer: stabalized inactivation of Na+ channels
Especially useful in treating mixed episodes and rapid-cycling bipolar, also used for trigeminal neuralgia Need CBC and LFTs before treatment Stevens-Johnson Syndrome, leukopenia, hepatitis, neural tube defects, aplastic anemia, agranulocytosis, autoinduction |
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Lamotragine
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Mood Stabilizer: stabalized inactivation of Na+ channels
Bipolar depression (not acute mania) Stevens-Johnson levels increased by valproate |
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Lithium
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Used to treat acute mania and help prevent relapses of manic episodes
Need ECG, basic chemistries, thyroid function tests, CBC, and a pregnancy test. SE: tremor, nephrogenic DI, ECG changes, Ebsteins's anomaly |
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Oxcarbazepine
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Mood Stabilizer: stabalized inactivation of Na+ channels
like carbamazepine but less risk of rash and hepatic toxicity |
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Topiramate
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Mechanism of action unknown
Helpful with impulse control and anxiety, beneficial side effect is weight loss can cause non-anion gap metabolic acidosis, kidney stones, and cognitive slowing |
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Valproic Acid
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↑ Na+ channel inactivation,↑GABA concentration
Monitoring LFTs and CBC is necessary normal range in blood 50-150 |
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Aripiprazole
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atypical antipsychotic
little weight gain/EPS partial D2 agonism can be more activiating (akathisia) and less sedating |
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Asenapine
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atypical antipsychotic
sublingual tab, little anticholinergic effects |
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Clozapine
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atypical antipsychotic
Lost of Sedation, Anticholinergic, orthostatic hypotension, weight gain 0 eps angranulocytsis and seizures |
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Iloperidone
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atypical antipsychotic
little eps, moderate weight gain |
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Olanzapine
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atypical antipsychotic
Large weight gain, little eps can inject, dissolve tab |
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Paliperidone
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atypical antipsychotic
moderate SE profile metabolite of risperidone, long acting injectable form |
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Quetiapine
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atypical antipsychotic
high sedation + orthostatic hypotension little eps/anticholenergic |
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Risperidone
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atypical antipsychotic
little anticholinergic can cause increased prolactin long-acting injectable available |
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Ziprasidone
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atypical antipsychotic
little weight gain, little anticholenergic can inject |
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Acetophenazine
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conventional antipsychotic
high potency |
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Chlorpromazine
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conventional antipsychotic
low potency (high anti-cholinergic and anti-histaminic, lower EPS) orthostatic hypotension, bluish skin, photosensitivity higher seizure rates than high potency |
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Droperidol
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conventional antipsychotic
high potency |
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Fluphenazine
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conventional antipsychotic
high potency decanoate form available |
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Haloperidol
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conventional antipsychotic
high potency decanoate form available |
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Loxapine
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conventional antipsychotic
medium potency higher risk of seizure |
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Mesoridazine
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conventional antipsychotic
Low potency |
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Perphenazine
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conventional antipsychotic
high potency |
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Pimozide
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conventional antipsychotic
high potency associated with heart block, vtach |
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Prochlorperazine
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conventional antipsychotic
high potency |
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Thioridazine
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conventional antipsychotic
low potency (high anti-cholinergic and anti-histaminic, lower EPS) associated with retinitis pigmentosa higher seizure rates than high potency |
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Thiothixene
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conventional antipsychotic
medium potency can cause ocular pigment changes |
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Trifluoperazine
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conventional antipsychotic
high potency can reduce anxiety |
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Buspirone
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Partial agonist at 5HT-1A
Slow onset of action, no abuse potential Anxiolytic |
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Gabapentin
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Often used adjunctively to help with anxiety, sleep
Little effect in bipolar |
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Pregabalin
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Used in GAD and fibromyalgia
Little effect in bipolar |
