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47 Cards in this Set

  • Front
  • Back
what are the low potency antipsychotics
chlorpromazine
thioridazine
what are the side effects of thioridazine
most cardiotoxic in OD
irreversible retinal pigmentation
what are the side effects of chlorpromazine
hepatic toxicity
derm problems (skin eruptions, discoloration)
deposits in lens and cornea
most sedating
are low or high potency antipsychotics more associated with neurologic side effects?
non-neurologic?
high potency
low potency
examples of high potency antipsychotics
haloperidol
perphenazine
fluphenazine
what are EPS
pseudoparkinsonism
akathisia
acute dystonia
aside from EPS what are other neurologic side effects
TD
NMS
decreased seizure threshold
how to treat acute dystonia
anticholinergic
antihistamine
how to treat NMS
stop the offending drug immediately
give skeletal muscle relaxant
provide medical support
switch to low potency med
how to treat TD
substitute low potency or atypical antipsychotic
how to treat pseudoparkinsonism
anticholinergic (genztropine, ex)
b/c DA normally suppresses ACh activity, if you give anticholinergic it will cause increased release of DA and relieve sx
can also tx with antihistamine
which neuro side effect takes >6mo to develop?
TD
Side effects of amitryptiline
sedation
anticholinergic
which HCA is most serotonin specific
clomipramine
which HCA is least sedating
desipramine
which HCA has the least anticholinergic effects
desipramine
which HCA stimulates appetite
desipramine
what are the effects of desipramine
least sedating
stim appetite
least anticholinergic
effets of doxepin
sedation
antihistaminergic
anticholinergic
which HCA is likely to cause orthostatic hypotension
imipramine
which HCA may cause seizures
maprotiline
which HCA has low cardiotoxicity
maprotiline
which HCA is LEAST likely to cause orthostatic hypotension
nortriptyline
other than depression, uses for amitryptiline
depresssion with insomnia
chronic pain
other than depression, uses for clomipramine
OCD
other than depression, uses for desipramine
panic do
depression in elderly
eating DO

(think of side effects)
other than depression, uses for doxepine
GAD
PUD
other than depression, uses for maprtoiltine
anxiety with depressive features
other than depression, uses for nortriptyline
depression in elderly
pruritus
pts with cardiac dz
which HCAs are good for treating depression in elderly?
nortriptyline
desipramine
General side effects from SSRIs?
SIG HAS
Sexual side effects
Insomnia
GI probs
HA
Anorexia
Serotonin syndrome (if given w MAOIs)
What are SSRIs used to treat?
OCD (fluvoxamine)
Premature ejac
Panic d/o
PMDD (fluoxetine)
Social phobia (paroxetine)
Hypochondriasis
Chronic pain
PTSD
paraphilias
which SSRI --> weight loss
fluoxetine
which SSRI --> agitation and insomnia
fluoxetine
"one FLU over the cuckoo's nest"
which SSRI is most sedating
paroxitine
which SSRI is most anti-cholinergic
paroxitine
which of sSRIs is most likely --> GI probs
sertraline
which SSRI is most cardiotoxic
citalopram
SNRI
Venlafaxine
duloxetine
5HT and NorE reuptake inhib
NDRI
buproprion
norE/DA reuptake inhib
SARI
Nefazodone
Trazodone
5HT antagonist and reuptake inhib
NASA
Mirtazapine
norE and 5HT antag
advantage to SNRIs
rapid sx relief
few sexual side effects
other than depression, uses of duloxetine
refractory depression
urine stress incontinence
other than depression, uses of venlafaxine
refractory depression
GAD
social phobia
contradindications for buproprion
seizures
eating d/o
psychosis (at higher doses, high DA effects)
mania
other than depression, uses of MAOIs
atypical depression
pain d/o
eating d/o
panic d/o
social phobia