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42 Cards in this Set

  • Front
  • Back
Amitriptyline
Elavil
(TCA)

for depression, migraine prophylaxis
Imipramine
Tofranil
(TCA)

for depression, panic disorder, enuresis
Nortriptyline
Aventyl
(TCA)

for depression, panic disorder, smoking cessation
Citalopram
Celexa
(SSRI)

for depression

Dose: 20 mg daily, increase 20 mg at > 1 wk intervals
Effective dose: 20-40 mg daily
Escitalopram
Lexapro
(SSRI)

for depression, GAD

Dose: 10 mg daily, increase 10 mg at > 1 wk intervals
Max 20 mg daily
Fluoxetine
Prozac
(SSRI)

for depression, OCD, bulimia, panic disorder

Dose: 20 mg daily
Max dose: 80 mg daily
Fluvoxamine
Luvox
(SSRI)

for depression

Dose: 50 mg qhs, increase 50 mg q4-7 days
Effective dose: 100-300 mg daily
Max: 300 mg daily
Paroxetine
Paxil
(SSRI)

for depression, GAD, OCD

Dose: 20 mg daily, increase 10 mg/day > 1 wk intervals
Effective dose: 20-50 mg daily
Max: 50 mg daily
Paroxetine (paxil) inhibits what CYP450?
2D6

avoid thioridazine, MAOIs, barbiturates, cimetidine, phenytoin, theophylline, TCAs, risperidone, warfarin
Sertraline
Zoloft
(SSRI)

for depression, OCD, PTSD, panic disorder

Dose: 50 mg daily, increase after 1 wk
Effective dose: 50-200 mg daily
Max: 200 mg daily

CI: pregnancy
Duloxetine
Cymbalta
(SNRI)

for depression, GAD, neuropathic pain

Dose: 20 mg BID
Max: 60 mg daily

CI: renal/hepatic insufficiency, alcohol use, inhibitor of CYP1A2, pregnancy
Venlafaxine
Effexor
(SNRI)

for depression, GAD, panic disorder,

Dose: 37.5 mg BID, increase 75 mg daily q4 days
Effective dose: 150-225 mg daily
Max: 375

CI: renal/hepatic insufficiency (decrease dose), pregnancy, serotonin syndrome with triptans
Bupropion
Wellbutrin
(NE/DA reuptake inhibitor)

for depression, smoking cessation

Dose: 100 mg BID, increase to 100 mg TID after 4-7 days
Effective dose: 300-450 mg/day
Max: 450 mg/day

CI: seizure d/o, eating d/o, alcohol w/d, MAOIs, children
Nefazodone
Nefazodone
(5HT2 antagonist)

for depression

Dose: 100 mg BID, increase 100-200 mg/day at > 1 wk
Effective dose: 150-300 mg BID
Max: 600 mg/day

SE: liver failure (monitor LFTs)
CI: kids, liver dysfunction
Trazadone
Trazarel

for depression (rare), insomnia

Dose: 50-100 mg qhs
Max: 150 mg/day

SE: priapism, CYP3A4 metabolism
Lamotrigine
Lamictal
(antimanic agent)

for bipolar,

Dose: 25 mg daily, increase to 50 mg daily after 3-4 wks
Target: 200 mg daily (after 5-7 wks)

SE: stevens-johnson syndrome
CI: pregnancy
Lithium
Eskalith
(antimanic agent)

for bipolar, acute mania

Acute mania: 300-600 mg BID-TID
Bipolar: 9000-1200 mg/day

Monitor: renal fnx, thyroid fnx
What is the therapeutic serum level of Lithium?
0.6-1.2 mEq/L

Diuretics/NSAIDs increase levels
Topiramate
Topamax
(antimanic, anticonvulsant)

for bipolar, alcohol dependence

Dose: 25-50 mg/day
titrate prn to max 400 mg/day

Monitor: renal function, weight loss, bicarb
Valproic acid
Depakote
(antimanic, anticonvulsant)

for mania, bipolar

Mania: 250 mg PO TID

SE: hepatic failure (children <2), monitor LFTs
Chlorpromazine
Thorazine
(typical antipsychotic)
Haloperidol
Haldol
(typical antipsychotic)
Aripiprazole
Abilify
(atypical antipsychotic)
Clozapine
Clozaril
(atypical antipsychotic)
Olanzapine
zyprexa
(atypical antipsychotic)
Quetiapine
Seroquel
(atypical antipsychotic)
Risperidone
Risperdal
(atypical antipsychotic)
Ziprasadone
Geodon
(atypical antipsychotic)
Clonazepam
Klonopin
(long acting benzo)
Diazepam
Valium
(long acting benzo)
Lorazepam
Ativan
(medium acting benzo)
Alprazolam
Xanax
(short acting benzo)
Oxazepam
Serax
(short acting benzo)
Triazolam
Halcion
(short acting benzo)
Buspirone
BuSpar
(anxiolytic)
Zaleplon
Sonata
(hypnotic)
Zolpidem
Ambien
(hypnotic)
Acamprosate
Campral
(maintenance of alcohol abstinence)
Naltrexone
ReVia, Depade, Vivitrol
(alcohol dependence)
Suboxone
buprenorphine + naloxone
(opioid dependence)
Tx for neuroleptic malignant syndrome
-D/C antipsychotic
-Dantrolene (muscle relaxant)
-Ativan/Valium
-Bromocriptine or Amantadine (D2 agonist)
-cool pt, give fluids and alkalinze urine to avoid renal fx
What antipsychotic causes the most weight gain and DM?
olanzapine (zyprexa)