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42 Cards in this Set
- Front
- Back
Amitriptyline
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Elavil
(TCA) for depression, migraine prophylaxis |
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Imipramine
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Tofranil
(TCA) for depression, panic disorder, enuresis |
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Nortriptyline
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Aventyl
(TCA) for depression, panic disorder, smoking cessation |
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Citalopram
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Celexa
(SSRI) for depression Dose: 20 mg daily, increase 20 mg at > 1 wk intervals Effective dose: 20-40 mg daily |
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Escitalopram
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Lexapro
(SSRI) for depression, GAD Dose: 10 mg daily, increase 10 mg at > 1 wk intervals Max 20 mg daily |
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Fluoxetine
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Prozac
(SSRI) for depression, OCD, bulimia, panic disorder Dose: 20 mg daily Max dose: 80 mg daily |
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Fluvoxamine
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Luvox
(SSRI) for depression Dose: 50 mg qhs, increase 50 mg q4-7 days Effective dose: 100-300 mg daily Max: 300 mg daily |
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Paroxetine
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Paxil
(SSRI) for depression, GAD, OCD Dose: 20 mg daily, increase 10 mg/day > 1 wk intervals Effective dose: 20-50 mg daily Max: 50 mg daily |
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Paroxetine (paxil) inhibits what CYP450?
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2D6
avoid thioridazine, MAOIs, barbiturates, cimetidine, phenytoin, theophylline, TCAs, risperidone, warfarin |
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Sertraline
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Zoloft
(SSRI) for depression, OCD, PTSD, panic disorder Dose: 50 mg daily, increase after 1 wk Effective dose: 50-200 mg daily Max: 200 mg daily CI: pregnancy |
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Duloxetine
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Cymbalta
(SNRI) for depression, GAD, neuropathic pain Dose: 20 mg BID Max: 60 mg daily CI: renal/hepatic insufficiency, alcohol use, inhibitor of CYP1A2, pregnancy |
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Venlafaxine
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Effexor
(SNRI) for depression, GAD, panic disorder, Dose: 37.5 mg BID, increase 75 mg daily q4 days Effective dose: 150-225 mg daily Max: 375 CI: renal/hepatic insufficiency (decrease dose), pregnancy, serotonin syndrome with triptans |
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Bupropion
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Wellbutrin
(NE/DA reuptake inhibitor) for depression, smoking cessation Dose: 100 mg BID, increase to 100 mg TID after 4-7 days Effective dose: 300-450 mg/day Max: 450 mg/day CI: seizure d/o, eating d/o, alcohol w/d, MAOIs, children |
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Nefazodone
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Nefazodone
(5HT2 antagonist) for depression Dose: 100 mg BID, increase 100-200 mg/day at > 1 wk Effective dose: 150-300 mg BID Max: 600 mg/day SE: liver failure (monitor LFTs) CI: kids, liver dysfunction |
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Trazadone
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Trazarel
for depression (rare), insomnia Dose: 50-100 mg qhs Max: 150 mg/day SE: priapism, CYP3A4 metabolism |
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Lamotrigine
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Lamictal
(antimanic agent) for bipolar, Dose: 25 mg daily, increase to 50 mg daily after 3-4 wks Target: 200 mg daily (after 5-7 wks) SE: stevens-johnson syndrome CI: pregnancy |
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Lithium
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Eskalith
(antimanic agent) for bipolar, acute mania Acute mania: 300-600 mg BID-TID Bipolar: 9000-1200 mg/day Monitor: renal fnx, thyroid fnx |
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What is the therapeutic serum level of Lithium?
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0.6-1.2 mEq/L
Diuretics/NSAIDs increase levels |
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Topiramate
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Topamax
(antimanic, anticonvulsant) for bipolar, alcohol dependence Dose: 25-50 mg/day titrate prn to max 400 mg/day Monitor: renal function, weight loss, bicarb |
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Valproic acid
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Depakote
(antimanic, anticonvulsant) for mania, bipolar Mania: 250 mg PO TID SE: hepatic failure (children <2), monitor LFTs |
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Chlorpromazine
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Thorazine
(typical antipsychotic) |
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Haloperidol
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Haldol
(typical antipsychotic) |
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Aripiprazole
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Abilify
(atypical antipsychotic) |
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Clozapine
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Clozaril
(atypical antipsychotic) |
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Olanzapine
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zyprexa
(atypical antipsychotic) |
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Quetiapine
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Seroquel
(atypical antipsychotic) |
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Risperidone
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Risperdal
(atypical antipsychotic) |
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Ziprasadone
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Geodon
(atypical antipsychotic) |
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Clonazepam
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Klonopin
(long acting benzo) |
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Diazepam
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Valium
(long acting benzo) |
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Lorazepam
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Ativan
(medium acting benzo) |
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Alprazolam
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Xanax
(short acting benzo) |
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Oxazepam
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Serax
(short acting benzo) |
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Triazolam
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Halcion
(short acting benzo) |
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Buspirone
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BuSpar
(anxiolytic) |
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Zaleplon
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Sonata
(hypnotic) |
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Zolpidem
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Ambien
(hypnotic) |
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Acamprosate
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Campral
(maintenance of alcohol abstinence) |
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Naltrexone
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ReVia, Depade, Vivitrol
(alcohol dependence) |
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Suboxone
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buprenorphine + naloxone
(opioid dependence) |
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Tx for neuroleptic malignant syndrome
|
-D/C antipsychotic
-Dantrolene (muscle relaxant) -Ativan/Valium -Bromocriptine or Amantadine (D2 agonist) -cool pt, give fluids and alkalinze urine to avoid renal fx |
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What antipsychotic causes the most weight gain and DM?
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olanzapine (zyprexa)
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