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69 Cards in this Set
- Front
- Back
Minimum duration of symptoms needed to diagnose depression |
Two wks |
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Core symptoms of depressive episode according to ICD-10 |
Low mood Anhedonia( lack of pleasure) Fatiguability/ lack of energy |
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How many DSM criteria should be there to diagnose depression |
5/9 |
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What is recurrent depressive dx |
Repeated episodes of mild/moderate/severe Depression without manic episodes with complete recovery in btwn episodes |
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Bipolar depression in comparison to unipolar depression.
1. Duration 2. Response to treatment 3. Previous hx of manic or hypomanic episodes |
1. Long duration 2. Poor |
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Rate of major depression in community samples |
2-5% |
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Life time rate of major depression |
10-20% |
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Major depression M:F ratio |
1:2 |
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Mean age of onset |
27 yrs |
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Duration of a depressive episode |
1-6 months |
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Percentage getting chronic lasting depression more than two years |
10-20% |
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Percentage experiencing more than one episode |
85% |
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Minor symptoms of depression- first three |
Reduced concentration and attention Reduced self esteem and self confidence Ideas of guilt amd unworthiness |
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Minor symptoms of depression- last 4 |
Bleak and pessimistic view about future Ideas or acts of self harm and suicide Disturbed sleep Diminished appetite. |
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How to differentiate grief from depression |
Grief- no low self esteem |
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Pseudodementia vs dementia |
Pseudodementia- more acute in onset, other symptoms of depression, respond to antidepressants |
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Common somatic symptoms of depression |
Body aches Back pain Burning sensation Fatigue |
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Differentiating depression vs schizophrenia, 1. Mood- 2. Delusions 3. Thought related- |
1. Low mood prominent( depression), psychotic symptoms prominent( schizophrenia) 2. Mood incongruent delusions( schizophrenia), mood congruent delusions- nihilism, guilt( depression) 3. Thought insertion, withdrawal, broadcasting, passivity( schizophrenia) |
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Depression vs schizophrenia 4. PPHx 5. FMHx |
4. Depressive or manic episodes( depression), psychotic episodes(schizophrenia) 5. Depressive or bipolar illness( depression), schizophrenia( schizophrenia) |
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To determine the severity of illness, number of symptoms as well as_______is important |
Degree of functional imapirment |
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Mild depression- diagnostic criteria |
2+2 None should be present to a severe degree |
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Functional level of mild depression |
Usually distressed by symptoms, Some diffculty in continuing ordinary work But do not cease to function completely. |
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Diagnostic criteria for moderate depression |
2+3/4 Several symptoms- at a marked degree. |
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Functional level of moderate depression |
Considerable difficulty in continuing social, work and domestic activity |
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Causes of depression- three main categories |
Bio Psycho Social |
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Biological causes of depression |
Genetic Physical Endocrine dx Medications Substance use |
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Psychological causes of depression |
Personality Relationship issues. |
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Social causes of depression |
Financial Marital Workplace Other stressors |
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Biological causes of depression- family hx |
Fmhx of depression, bipo dx, suicide |
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Biological causes of depression. Pmhx |
Any chronic illness ( malignancy, mi, stroke, epilepsy, parkinson dx, renal and liver dx, chronic pain, DM, SLE) |
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Biological causes of depression- medications |
Analgesics usage Antibiotics Antihypertensives
chemo Steroid Immunosupressants |
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Biological causes of depression- substance use hx |
Alcohol Cannabis Heroine (/quantity. Frequency and duration of use) |
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Biological causes of depression- physical examination |
Features of physical illness and endocrine dx |
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Biological causes of depression-lab ix |
Relevant ix according to hx Urine for drug screen |
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Diagnostic criteria for severe depression |
3+4 Some symptoms- to a severe degree |
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Can diagnosis of severe depression made if duration less than 2 wks |
Yes. If symptoms are very severe nd of rapid onset |
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Functional level of severe depression |
Unable to continue activity |
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Delusions of gult inoves ideas of |
Sin Poverty Imminent disasters Responsibility for bad things |
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Examples of delusions of nihilism |
Internal organs are destroyed. Dead Lost all possessions |
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Examples of auditory hallucinations in depression |
defamatoryAccusatory |
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Examples of olfactory hallucinations in depression |
Rotten flesh etc. |
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Examples of long term relationship problems leading to depression- Relationship with mom- role in depression.? Social stressors leading to depression- Positive events that can lead to depression- |
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Risks to self- Risk to others- |
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Indicators of high suicidal risk 1. Thoughts- 4 2. Past hx 3. Lack of-2 4. Availability-1 5. Habits-1 Wherw do you get info to assess risk-2 |
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How to assess the risk of self neglect 1. Hx 2. Examination- |
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Psychosocial Aetiology of depression. Current stressors- Personality assessment- 1. Coping strategies- 2. Relationship- 3. Personality- |
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4 endocrine dx well lnown to cause depression |
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How family members and workmates give social support |
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Details about previous episodes 1. Frequency- 2. Details of individual episodes- 3. Treatment- 4. Response to treatment- 5. Interepisode period- 6. Precipitated factors- |
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Goals of treatment- first 4 Goals of treatment- second 4 Indications for admission- Outpatient mx- two things done at each clinic review. |
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Education of pt and family 1. What is depression- 2. Rx options- 3. Time taken to respond- 4. SE 5. How long to continue- How to respond to their cultural views? |
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Steps to provide supportive environment- In ward- Outpatient- |
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Minimizing harms- 1. In a psych ward- 2. If sent to a non psych ward- |
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1. How to minimize harm at home- 2. If trying to harm others better to- 3. Which groups are vulnerable to self neglect- 4._______ preferred in self nglect risk |
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1. Psychotic depression- combination of_________ better than antidepressants. 2. BP depression- drug classes 3. Efficacy of TCA vs SSRI? (Then why SSRI preferred?) |
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Factors affecting medication choice? 2 most effective SSRI s? Fluoxetine more effective in______ SSRIs should be used cautiously in children and adolescents bcz________ TCA- effective in severe depression, but not the first choice why? ____________more effective than ssri for severe depression. |
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SNRI- CVS se? Why MAOI rarely used? TCA contraindications- TCA best avoided in bcz of- |
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Rare fatal se of antidepressants in elderly- TCA overdose se- TCA in pt with suicidal risk? SNRI safety? Cheapest antidepressant class Cheapest SSRI? |
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Previous Rx hx in choice of antidepressants- Role of pt preferance in choice? |
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Time to appear se? Time taken to give response? SSRI starting dose( concept) Why lower doses of SSRI for elderly? Why not to stop abruptly? Withdrawal symptoms of SSRI? How TCA started? Why slow dose titration with TCA? If poor response after two wks? When to change drugs? Which symptoms improve earlier than others? |
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Structure to analyse info during assessment- 2 |
Risk assessment Identifying social support Reasons for relapse Details of previous episodes. |
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SSRIs- why to carefully use when there are physical comorbidities |
Bcz enzyme inhibition Poor elimination in hepatic failure |
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SSRIs- the most potent cyt p450 inhibitors |
Fluoxetine Paroxetine |
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SSRI- least potent cytp450 inhibitors |
Citalopram Sertraline |
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Steps-to ensure safe antidepressant use when there are physical comorbidities |
Laise with physician Start lower doses and slowly titrate |
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How to minimize risk of relapse |
After first episode- rx at least 6 months Recurrent episodes- long term Rx If recurrent- Lithium, CBT- reduce risk of relapse |
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Indications for ECT |
Psychotic features Stupor Risk of self harm, self neglect Postpartum depression Poor response to meds |
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No. Of ECT cycles/ wk |
2-3 |
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Total number of ECT cycles/ per cycle |
6-12 |