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136 Cards in this Set

  • Front
  • Back

DSM-V Major Depressive Disorder

5 or more over 2 weeks


Mood change (every day)


Energy


Sleep


Interest


Guilt


Concentration


Appetite


Psychomotor


Suicidality


MFP

Melancholic Dperession

Typical old lady picture:


Worse in the morning. Loss of weight. Catatonic

Atypical Depression

Typical teenager depressed picture:


Eating lots, gaining weight, sleeping less, worse in afternoon.

Postpartum blues definition

Transient mild depression following childbirth (affects 80% of mothers) lasts up to 10 days

Depression with a peripartum onset

Mood disturbance onset within 4 weeks postpartum (can begin during pregnancy). Typically lasts 2-6 months, residual symptoms can last 1 year.

Definition of Persistent Depressive Disorder (Dysthymia)

Depressed mood for most of the day, more days than not, for at least 2 years. During the two years never been without symptoms for 2 months


2 or more of the symptoms of MDD

Lifestyle factors

SEERS


Sleep


Exercise


Eating Healthily


Relationships


Stress - Hobbies

Warning when starting anti-depressants

Take 14 days to be affective (but energy improved therefore increased suicidality). Trial of 6 weeks is required for an adequate trial of antidepressants.

When changing antidepressants

Must have antidepressant free interval

SSRI options

Citalopram - 20mg-40 mg taken morning


Fluoxetine - under 21


Sertraline

SNRI's

Venlafaxine


Duloxetine


Mirtazapine - weight gain

What drug is contraindicated with SSRI + SNRIs

Tramadol

2nd line options for antidepressants

Reversible MAO inhibitor


Irreversible MAO inhibitor - cheese effect (hypertension, intracranial haemorrhage --> death)


TCA - amitriptyline, clomipramine

TCA overdose presentation

Anticholinergic effects


Prolonged QRS


Rhabdomyolysis


Renal failure


Metabolic acidosis

Presentation in Serotonin Syndrome

Caused by Combination not overdose


CAN


Cognitive - Agitation, confusion


Autonomic - hyperthermia, diaphoresis


Neurological - hyperreflexia, tremor,

Mx Serotonin syndrome

Cease medication


Sedate - benzo


Cyproheptadine

Presentation in NMS

Antipsychotics - increased dosage


FARM


Fever


Autonomic Changes


Rigidity of Muscles


Mental State Changes

Management of NMS

Dantrolene - muscle relaxant


Bromocriptine - dopamine agonist

DSM V for mania

Abnormality for at least 1 week most of the day nearly every day/hospitalised


GST PAID


Grandiosity


Sleep


Talkative


Pleasure/Pain


Activity/Agitation


Ideas (flight of)


Distractibility


MFP

DSM V hypomanic

4 consecutive days/ never hospitalised

Management for MDD

Admit?


Bio - rule out organic, antidepressants, ECT


Psycho - CBT, IPT, psychodynamic, supportive psychotherapy, mindfulness based


Social - social worker referral, social skills support, optimise lifestyle

DSM V adjustment disorder

Within 3 months of stressor, out of proportion to intensity of stressor, MFP, once stressor subsides does not persist for more than 6 months

Sodium valproate considerations + AE

Narrow therapeutic window


Can be used with lithium.


Causes weight gain, liver, pancreas dysfunction

Depression vs grief

G: loss/empty, waves, associated with reminders, can experience joy, wants to joint deceased


MDD: depressed, persistent, no associated reminder, life's not worth living

Delusions vs overvalued idea

Delusion held with absolute conviction, overvalued idea is not 100% firmly held.

Nihilistic delusions

A belief that one is dead or a catastrophe will occur

Capgras syndrome

Delusion of doubles (someone's been replaced by an imposter)

Lycanthropy

Delusion that the person is a werewolf or other animal

DSM V delusional disorder

The presence of one or more delusion for 1 month or more AND


NOT schizophrenic


Functioning NOT impaired


MP

Brief psychotic disorder

schizophrenic symptoms, 1 day or more but less than 1 month


MFP

Schizophreniform

More than one months but less than 6 months

Schizophrenia DSM V

2 or more of the following in aperiod of greater than 6 months


Delusions


Hallucinations


Disorganised speech


Grossly disorganised or catatonic behaviour


Negative symptoms


MFP

Tactile hallucination

False perception of touch or surface sensation

Formication

Crawling sensation on or under the skin

Schizoaffective disorder DSM V

1- Uninterrupted period of illness during which there is a major mood episode concurrent with schizophrenia


2- 2 weeks of delusions or hallucinations alone during the course of the illness without mood



MFP

Differentials for psychiatry

MOAPP


Mood


Organic


Anxiety


Psychotic


PD


Suicidality/Risk

EPSE's and Mx

Acute dystonia - Benztropine


Parkinsonism - Benztropine


Akathisia - Diazepam or propanolol


Tardive dyskinesia - Switch to clozapine

Switching between antipsychotics

1-2 week crossover

Second generation/Atypical antipsychotics

5-20mg Olanzapine - metabolic syndrome


Quetiapine - sedation


2-8mg Risperidone - hyperprolactinaemia


Sertindole - QT prolongation


Paliperidone


Aripiprazole

Management of a dangerous acutely psychotic patient who will not accept oral

Midazolam IM

Clozapine councelling

Good for negative symptoms and treatment resistant


200mg-600mg


AE: agranulocytosis, myocarditis, matbolic syndrome - diabetes & weight gain


Monitoring: FBEs weekly for a month then fortnightly. Before commencing needs FBE, Echo, BSL, cholesterol and weight


Depot antipsychotics

Risperidone consta


Aripiprazole


Paliperidone


Olanzapine (still patent)


Zuclopenthixol decanoate (WAS IN QUIZ!!!)

DSM V panic disorder

recurrent unexpected panic attacks followed by 1 month or more of persistent concern about consequences of panic attack or maladaptive change in behvaiour


MFP

Panic attack criteria DSM V

4 out of


STUDENTS FEAR the 3 C's


Sweating


Trembling


Unsteadiness


Depersonalisation


Excessive Heart rate


Nausea


Tingling


SOB


Fear of dying, losing control, crazy


3 C's: Chest pain, chills choking

Agoraphobia DSM V

Marked anxiety about 2 or more of the following'


- using PT


- open spaces


- closed spaces


- standing in crowd


- leaving home alone



lasts for 6 months


Can have panic disorder with agoraphobia

Generalised anxiety disorder DSM V

Excessive anxiety and worry most days for at least 6 months in a number of settings.


3 or more of the following


BESKIM


Blank mind (concentration), Easily fatigued, Sleep disturbance, Keyed up, irritable, Muscle tension


ASK: worry often, hard to control worry, what worries you

PTSD DSM V

TRAUMA


Traumatic event


Reliving the trauma


Avoiding associated stimuli


Unable to function


More than a month


Arousal increased

Management anxiety disorders

Bio - SSRIs/SNRIs (benzos in acute setting)


Psycho - CBT, relaxation, Mindfulness based therapy, psychotherapy


Social - sleep hygeine, diet, exercise, avoid caffine/ETOH, counselling, exposure therapy, IPT

ECT explanation

Given 3x week 2-4 weeks


usually stop other medication unless acutely unwell


AE: headache, memory loss, muscle aches, small risk of death, anaesthesia


C/I: recent MI, raised ICP, aneurysm, bleeding disorder, Pacemakers

Causes of Delirium

Drugs


Eyes&ears (sensation)


Low oxygen (PE, AMI, stroke)


Infection


Retention


Ictal state


Under nutrition
Metabolic - hypoglycaemia, hyponatraemia, hypothyroidism

Compare and contrast the different types of dementia

Alzheimers (60%) - Aphasia, apraxia, agnosia, executive function


Vascular - stepwise


Lewy body - parkinsonism, visual hallucinations, fluctuating cognition


Frontotemporal- disinhibition, memory sparing, decreased social awareness

Management of alzheimers

Optimise physical and mental health


Challenging behaviour, alagesic, antidepressants


Cholinesterase inhibitor donepezil (MMSE <12) - cholinergic

Reversible causes of dementia

Intoxication or withdrawal (wernicke'korsakoff)


Medication


Hypothyroidism


NPH (AID)


Chronic subdural haematoma


Pseudodementia

Pseudodementia vs. dementia

PD - acute onset, emphasis failures, 'don't know'


D - insidious onset, delights in accomplishments, sundowning common, guesses answers

Pharmacotherapy for ADHD

Methylphenidate (ritalin) dexamphetamine


SSRI

Management for ADHD

Bio - Methylphenidate (ritalin) dexamphetamine


Psycho - social skills training, family therapy, anger control


Social - parental Mx & education, positive reinforcement, classroom intervention

ODD vs conduct disorder

ODD - gets angry lots


CD - Violates others

Autism assessment

ADOS, hearing and visual, neurological evaluation (exclude epilepsy) karyotyping, FBC/dietary assessment, Denver II,

Management Autism

Early intervention


Multidisciplinary - school, psychologist, OT, physio, Speech therapy, paediatrician, psychiatrist


Family education


Pharmacotherapy - SSRI

Substance Abuse vs dependence

Abuse: Not fulfilling obligation, causing danger to themselves or others, legal problems, interferes with function


Dependence: Tolerance, in larger than intended amounts, recurrent attempts to cut down, replacing other activities

Mx Alcohol dependence

Bio - Naltrexone (reduce craving), disulfiram (makes uncomfortable - can be dangerous), acamprosate (can cause impotence), thiamine


Psycho - motivational interviewing, behvaiour modification


Social - supportive services e.g. halfway houses, AA, detox centres

Delirium tremens

stage 4 of alcohol withdrawal.3-5 days after last drink


Confusion, delusions, hallucinations, agitation, tremor, autonomic hyperactivity


Benzo's!!

Mx alcohol withdrawal

Diazepam, thiamine

Wernicke-Korsakoff syndrome

Wernicke's encephalopathy - nystagmus, ophthalmoplegia, ataxia, confusion


Korsakoff's syndrome - chronic, 20% are reversible. Anterograde amnesia



THIAMINE!!!!

Opiate overdose management

DRABC - naloxone

Long term management opiate withdrawal

methadone once daily at clinic. CBT, counselling, social support

BMI ranges

under 18.5 - underweight


18.5-25 - normal


25-30 - overweight


30+ - obese

Anorexia complications

Hypochloraemic hypokalaemic alkalosis


Amenorrhea


osteoporosis


Dry skin/brittle hair


Postural hypotension


Vitamin deficiency


Bradycardia/arrhythmia (hypokalaemia)



Difference between bulimia and anorexia

Bulimia - can't control their eating, binge and then regret - maintain insight


Normal BMI usually


More likely to self harm/ substance abuse


Worse prognosis in bulimia


Cluster A personality disorders

Schizoid - doesn't like others, loner, withdrawn, aloof, cold


Schizotypal - wants relationships but hasn't got social skills. Also has magical thinking


Paranoid - suspicious

Cluster B personality disorders

Histrionic - dramatic, centre of attention, egocentric, vain, shallow


Antisocial - Unlawful, lies, steals, delinquent, criminal


Narcissistic - Grandiosity, self importance, entitled


Borderline - instability in mood, unstable identity, intense anger, empty

Cluster C personality disorders

Avoidant - Hypersensitive to potential rejection or shame, social withdrawal, needs affection


Dependent - Doormat, passive, needs to be taken care of


Obsessive compulsive - perfectionist, indecisive, preoccupation with order and control, egosyntonic


Psychotherapy for borderline PD

DBT

When to use psychodynamic psychotherapy

Past events predispose to current problem. Deal with that past event, clarify emotions, rarely confront

When to use interpersonal therapy

Role transition (loss of loved one, new mother) role disputes (work of relationship issues)

When to use family therapy

Any disorder where multiple members of the family are indicated/ causing the tension


Eating disorders are a big one

Risk assessment components

MYREASON


Medication non-compliance


Young or dependent harm


Reputation


Exploitation


Absconding


Suicide/self harm


Oh dollaazz


Neglect

SSRI adverse effects

SHINAS


-Sexual dysfunction


-Headache


-Insomnia


-Nausea & diarrhoea


-Anxiety and restlessness


-Serious: suicide and SS

Define malingering

Intentional production of false physical or psychological symptoms motivated by an external reward - avoiding work, financial compensation

Define Factitious Disorder

Feigning psychological or physical symptoms in order to assume the sick role where external incentives are absent

Somatic Symptom Disorder

One or more somatic symptom with excessive thoughts, feelings or behaviours related to the symptom that are - disproportionate, cause anxiety, time and energy devoted.


6 months


MFP

Illness anxiety disorder

Preoccupation with having or acquiring a serious illness - no symptoms, anxiety about health


6 months + MFP


(Previously hypochondriasis)

Conversion disorder

Functional neurological symptom disorder


Symptoms of altered voluntary motor or sensory function


Do not make sense and neurological assessment cannot find anything

Autochthonous delusion

'Out of nowhere' realises something bizarre, doesn't understand why they didn't realise before.

Clang associations

Playing with words, stringing together words that sound similar with different meanings or rhyme

Stereotypy

Repeated complex series of movements 'habit'. Waving hand then brushing tie

Tic

Repetitive uncontrolled short action, e.g cough

Pharmacotherapy for Generalised anxiety disorder

1. SSRI


2. Venlafaxine/duloxetine

When to use supportive therapy

listen & clarifying emotions


Management in psych always!

Psychoeducation


Psych first aid - exercise, diet, drug, community program


Psychotherapy


Pharmacotherapy


ECT

Pt is depressed and needs to gain weight and eat and sleep. What drug

Mirtazapine

Symptoms of lithium overdose

Diarrhoea, N/V


CNS - hyperreflexic, tremor, confusion


Cardiac - QT prolongation

Criteria for involuntary treatment

1. Person must appear mentally ill


2. Person must require immediate treatment


3. Involuntary treatment is necessary


4. Refused consent or unable to consent


5. Cannot be undergone in a less restrictive manner


Questions to ask for Antisocial Personality Disorder

Have you been in trouble with the police?


Would you be described as honest?


Do you plan ahead?


Irritable or aggressive?


Longest in relationship/job?


Remorse?


How long?

Question to ask for paranoid personality disorder?

Others exploiting or harming?


Trust others?


Grudges?


Spouse cheating?


Hidden negative meanings in events?

Question to ask for schizoid personality disorder?

Friends?


Alone or in group? (alone)


Sexual partners?


Activities you enjoy?


Opinions of others important to you?

Questions to ask for schizotypal personality disorder?

Do you see things other people don't see?


Things are referring to you?


Odd/eccentric?


Social anxiety?


Friends?

Questions to ask for histrionic personality disorder?

Do you need to be the centre of attention?


Sexually seductive?


Easily influenced?


Concerned with physical appearance?


Questions to ask Borderline personality disorder?

Impulsive?


Anger?


Suicide/self harm?


Stable sense of self/labile mood?


Scared of being abandoned?


Feel empty?

Questions to ask narsissistic personality disorder

Important?


Dream of unlimited success?


Jealous?


What kind of people do you surround yourself with?

Questions to ask avoidant personality disorder

Avoid activities with interpersonal contact?


Restraint within intimate relationship

Things you need to know about OCD

Obsessions: intrusive and unwanted + attempts to ignore thoughts


Compulsions: Feels driven to perform + aiming to reduce anxiety


- time consuming

Explaining CBT to a patient

Talking therapy


Focuses on here and now


Recognition that conscious thoughts rather than deeper feelings - look at things differently


Usually one-to-one


Occurs once-a-week for 8-12 session


Patient will get homework

Lithium counselling

Mechanism unknown - but very effective


Pre test - ECG, renal function, TFT


Regular blood monitoring - lithium levels, TFT, creatinine, urinalysis, ECG


Once a day at night


AE - initial: Metalic taste, tremor, N/V, polyuria/polydipsia


AE - long: Renal problems (Diabetes insipidus), weight gain, Thyroid, acne, teratogenic (+breast feeding)


Acute toxicity: DIARRHOEA, N/V, Coma, seizures, ataxia


Usually lifelong, at least a year



severity of Alzheimer's

Severe: 0-11


Moderate: 11-18


Mild: 19-24



If well educated move them up a severity rating

Person who is on an antidepressant becomes confused on a really hot day. What drug causes this?

SSRI's - hyponatraemia

Cause of left sided hemispatial neglect

Right parietal lobe lesion (non dominant)

Temporal lobe lesion causes

Memory and language

Frontal lobe lesion causes

Executive functioning

Restricted vs blunted vs flat affect

Restricted - mildy reduced


Blunted - very reduced (schizophrenia)


Flat - nothing

Delusion vs overvalued idea vs obsession

Delusion: fixed, false belief that usually cannot be swayed (illogical reason for it)


Overvalued idea: Not held with as much conviction - they question it! (they don't make up illogical reasons)


Obsession: recurrent intrusive thoughts that patient recognises as irrational and may find distressing or try to resist

Flight of ideas vs loosening of association

FOI: Abnormal connection between statements (no meaningful connection, rhyme or pun)


LOA: There is no association


Tangentiality vs circumstantiality

Tangentiality: Speaker never gets to the points, always speaks of irrelevant things


Circumstantiality: Indirect and delayed reaching the point, lots of parenthetical remarks

Schizoid PD vs Schizotypal PD

Schizoid:


Detachment from scoial relationships, restricted range of expression of emotions. Loner


Schizotypal:


Uncomfortable in social situations but wants to be involved. Fantasy thinking. Crazy

Poor memory + walking problems + confused + fluctuating + visual/auditory hallucinations

Dementia with Lewy bodies

Renee, aged 66 became upset about 6 months ago as someone was stealing from her. Usually these were small inexpensive but last week the pearl necklace belonging to her mother went missing. In the absence of signs of forced entry, she was obliged to conclude that her daughter had used her key to take it (and presumably the other things as well).

Alzheimers disease with psychosis

Patient on clozapine stable for 6 months. He has a monthly FBE which is normal, what investigation?

Echo

What investigation do you do for alzheimers

MRI brain

Man with visual hallucinations 3 days after being admitted for surgical treatment of injuries sustained in MVA. What drug caused the side effects?

Diazepam

Chronic pain + maximum dose of analgesia + tried all antidepressants + getting worse


Mx?

Supportive therapy

Therapy used when dealing with a current manifestation of a previous deep psychological trauma


i.e. struggles with authority figures, hated parents when younger

Insight orientated

Man + delusion that dying of cancer + thinks he deserves it. Diagnosis?

MDD with psychotic features

Man in hospital following a fall + initially well but now confused + fluctuating cognition + ants over flaw + Problems with short term recall. Diagnosis?

Delirium tremens


visual hallucinations common

Old lady acutely confused investigation?

UTI - urine microscopy and culture

After partial response to treatment patient became very agitated with excessive persipiration after dose was increased

SSRI (causes anxiety and sweating)

Levels of depression and management?

5/9 - mild - CBT


7/9 - moderate - SSRI/SNRI


9/9 severe - Admission SSRI ECT

Someone refuses to eat because so depressed. Mx?

ECT

Man very stressed at work. Needs something to tide him over the next few weeks.

Oxazepam

Patient presents with delusion what do you need to ask

Why do you think that?


What would you say if I disagreed with you?

MMSE findings in OSCE what they mean

NOT diagnostic - screening test. Say you'd refer to specialist but MMSE is "consistent with dementia"


Above 26 is normal but take into account tertiary education

Acute delirium management

Haloperidol

Dose of citalopram

20-40mg

Dose of fluoxetine

20-80mg

Dose of Risperidone

1-5mg

Dose of clozapine

200-600mcg

Dose lithium

125-500mg