Psych 2020 Midterm 3 - Opiates

Front 1

what were the first drugs labelled as 'narcotics'

Back 1

opiates

Front 2

the principal form of opiates for many centuries was ____

Back 2

opium

Front 3

describe what opium looks like and where its found

Back 3

its a gummy, brown residue collected from the opium seed capsule

Front 4

what is laudanum?

Back 4

a medicinal drink containing opium and wine

Front 5

what medicinal drink contained opium and wine?

Back 5

laudanum

Front 6

what drug is associated with 'chasing the dragon'?

Back 6

opium

Front 7

when did the opium war occur

Back 7

1840s

Front 8

opium was isolated in ___ and was called ____ after ___

Back 8

opium was isolated in 1803 and called morphium after the greek god of dreams, morpheus

Front 9

the use of morphine as an analgesic was vastly improved in the 1800s with the invention of

Back 9

the syringe

Front 10

what was soldiers disease

Back 10

morphine addiction during the american civil war

Front 11

what's another name for laudanum

Back 11

paregoric

Front 12

what drug was often given to children to chill them out?

Back 12

morphine in the form of patent medicines such as Ms Winslow's Soothing Syrup

Front 13

what was Ms Winslows soothing syrup

Back 13

a patent medicine containing opium used to sedate kids to get them to shut up

Front 14

t/f the harrison narcotic act of 1914 banned opium

Back 14

false. it did not intitially.

Front 15

what did the harrison narcotic act of 1914 have to say about opium

Back 15

it was not outlawed but doctors had to keep detailed records of prescriptions and pay a small fee

Front 16

an anti-chinese crusader from san fran visited vancouver and set off a riot in what year?

Back 16

in 1907

Front 17

what are the three main reasons william lyon mackenzie king wanted to stop opium trade in canada

Back 17

1. trade violated christian ideals

2. chinese were making huge profits

3. use was increasing among white men and women

Front 18

t/f william lyon mackenzie kings initial report on opium denounced its use due to its harmful medical effects

Back 18

false. he denounced its use because

1. trade violated christian ideals

2. chinese were making huge profits

3. use was increasing among white men and women

Front 19

what was the first drug legislation in canada?

Back 19

the 1908 opium act

Front 20

t/f the first drug legislation in canada predates the harry anslinger act

Back 20

yes. 1908 is before 1914

Front 21

what is the main difference between the 1908 opium act and the 1911 opium and drug act

Back 21

in 1908 posession was legal, however in the 1911 opium and drug act, posession was made illegal, allowed police to search and seize, and cocaine was made illegal

Front 22

inital drug clinics in the 1920s very successful

Back 22

false. they failed miserably

Front 23

who led the racially charged anti drug prejudice in canada?

Back 23

emily murphy

Front 24

what racially charged book did _____ write? under what pen name?

Back 24

emily murphy wrote the book 'the black candle' under the pen name 'Janey Canuck'

Front 25

what did the 1929 opium and narcotic drug act add? 4 things

Back 25

1. maintenance doses were no longer accepted medical practise

2. cannabis was included

3. right of seizure of property

4. write of assistance (could not be refused by judges)

Front 26

what are the most important alkaloids in opium

Back 26

1. morphine

2. codeine

3. thebane

Front 27

thebane is the source of ____ found in which two drugs

Back 27

thebane is the source of oxycodone found in percocets and oxycontin

Front 28

why is heroin more potent than morphine?

Back 28

the addition of the two acetyl groups onto morphine makes it more lipid soluble and less ionized, allowing it to cross the blood brain barrier with ease

Front 29

heroin was introduced to treat what?

Back 29

coughs and chest pains

Front 30

oxycodone when combined with aspirin is called?

when combined with acetominophen is called?

in a time release form is called?

Back 30

oxycodone when combined with aspirin is called percodan

oxycodone when combined with acetominophen is called percocet

oxycodone in a time release capsule is called OxyContin

Front 31

what is poor man's heroin/hillbilly heroin?

Back 31

OxyContin

Front 32

street prices of oxycontin are __ times the prescription price

Back 32

street prices of oxycontin are 10 times the prescription price, even though it's called hillbilly heroin

Front 33

how were oxycontin users able to bypass the time release mechanism before the formulation changed?

Back 33

they crushed the pills

Front 34

what drug has overtaken Oxycontin as the most abused prescription opiate?

Back 34

oxymorphone/opana

Front 35

what is the generic name of Opana

Back 35

oxymorphone

Front 36

hydrocodone combined with ____ is known as vicodin

Back 36

hydrocodone with acetominophen

Front 37

vicodin is ______ combined with _____

Back 37

hydrocodone combined with acetominophen

Front 38

t/f methadone was developed in germany as a substitute for dwindling morphine and is currently used in opiate treatment programs

Back 38

true

Front 39

suboxone contains a combination of what?

Back 39

buprenorphine and morphine

Front 40

how is suboxone used in opiate treatment programs

Back 40

the pill contains buprenorphine and naloxone. if the pill is crushed and injected , it is a partial agonist

Front 41

t/f fentanyl is more potent than heroin

Back 41

true

Front 42

t/f Narcan (naloxone) can only be administered via injection

Back 42

true

Front 43

t/f non injection use of heroin increases with increasing purity

Back 43

yes, because there is a greater chance of overdosing when the purity goes up

Front 44

what is past year use of nonmedical opiates in university

Back 44

5%

Front 45

what is past year use of prescription opiate use by high schoolers

Back 45

15%

Front 46

t/f injection is the most commmon form of opiate administration

Back 46

false. oral is.

Front 47

t/f injection is the most common form of heroin administration

Back 47

true

Front 48

what is doda?

Back 48

opium tea

Front 49

t/f nodding is an effect of opiates

Back 49

true

Front 50

opiate use causes release of histamine. what does this cause?

Back 50

itching

Front 51

t/f opiates dilate pupils

Back 51

false. pinpoint pupils

Front 52

t/f opiates causes increased sex drive

Back 52

false. it decreases sex drive

Front 53

t/f tolerance does not develop to analgesic effect of opiates

Back 53

false. it does develop to this effect

Front 54

are opiates rewarding?

Back 54

hell yeah

Front 55

what are the 3 receptors related to opiates

Back 55

1. Mu receptors

2. sigma receptors

3. delta receptors

Front 56

what are Mu receptors associated with neurochemically

Back 56

inhibiting GABA, which increases dopamine in the VTA

Front 57

what is the endogenous opiate receptor ligand?

Back 57

endorphins!

Front 58

t/f pavlovian conditioning plays a crucial role is opiate tolerance

Back 58

true

Front 59

t/f 'cold turkey' look is an effect of opiates

Back 59

no. it is a withdrawal symptom

Front 60

opiate withdrawal symptoms mirror that of?

Back 60

the flu

Front 61

what percent of those treated and released for opiate addiction has used within the first 6 months of release?

Back 61

80%

Front 62

name 2 advantages of methadone over heroin

Back 62

1. can be taken orally

2. longer duration of action

Front 63

when did methadone maintenace program start in the US, and by who?

Back 63

1958 by Dole and Nyswander

Front 64

what percent of people stay on methadone maintenance their entire lives?

Back 64

80%. so only 20% are able to quit

Front 65

t/f patients must be 6 month users of opiates and drug free to enter methadone maintenance

Back 65

false. they must be a 2 year user of opiates and drug free to enter methadone maintenance