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16 Cards in this Set
- Front
- Back
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Classification |
Phylum:Euglenozoa Order: Trypanosomatida Family: Trypomastidae Genus: Leishmania |
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Characteristics |
Heteroxenous promastigote in fly, amastigote in vertebrate tissue Reside in macrophages in vertebrates |
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Forms |
Promastigotes Amastigotes |
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Types |
Visceral Cutaneous Mucocutaneous |
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Visceral |
Kala azar/ dum dum fever Most serious weight loss, fever, enlarged spleen |
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Cutaneous |
Most common Ulcers: Jericho boil, Aleppo boil, and Delhi boil Asia & Americas |
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Mucocutaneous |
Causes long lasting lesions Destruction of mucous membrane of nose, mouth, throat Bolivia, Brazil, Peru |
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Types of protozoa |
L. Mexicana, tropica, donovani |
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Vector |
Sandfly phlebotomine |
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Result of |
Poor living conditions |
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Life cycle |
Human Blood meal by sandfly Promastigotes phagocytised by macrophages Promastigotes transform to amastigotes in macrohpages Amastigotes multiply in cell Sandfly sandfly takes a blood meal Ingests parasitised cells Amastigote transform into Promastigotes Divide in midgut and migrate to proboscis |
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Diagnosis |
Scraping from ulcer (Amastigotes) |
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Symptoms |
Anemia, enlarged spleen, fever, death |
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Countries |
East Africa eg. Ethiopia India |
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PKDL |
Post kala azar dermal leishmaniasis After visceral leishmaniasis East Africa & India |
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Treatment |
Antimonial compounds eg sodium stibogluconate |
