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23 Cards in this Set
- Front
- Back
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What is the vector for leishmania |
Female sandfly |
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Which cell in the body does leishmania multiply |
Macrophage |
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In sandfly parasite occurs in which form |
Promastigote |
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Who are two broadtype of clinical disease caused by leishmania |
Visceral Cutaneous |
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What are the species found in leishmania donovani complex |
L.donovani. L.infantum L.chagasi |
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What are the two disease caused by L.donovani |
Kala azar Post kala azar dermal leishmaniasis |
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Describe the life cycle of leishmania donovani |
1.When infected vector sandlfy feed on human inject promastigote stage into the skin 2.promastigote are phagocytized by macrophages 3.Promastigote are transformed into amastigote inside macrophages 4.amastigote multiply in macrophage of varioud tissue 5.sandfly takes a meal on infected person ingest macrophage infected with amastigote 6.macrophage rupture to release amastigote 7.amastigote transform into the promastigote form in the midgut
8.promastigote undergoes multiplication by longitudinal binary fission and migrate to the proboscis 9.infected sandlfy take blood meal on human injecting promastigote stage into the skin |
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What is the causative of indian visceral leishmaniasis and what is its vector |
L.donovani Vector is phleobotomud argentipes |
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What is the causative of middle eastern leishmaniasis and its vector |
L.donovani infantum and phelbotomus perniciosus,phelbotomus ariasi |
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What is the causative of east african leishmaniasis and its vector |
L.d.archibaldi Vectors p.orientalis,p.martini |
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What is the causative of southamerican leishamniasis |
L.d.chagasi Vector lutzomyis longipalpis |
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What are the clinical features of black sickness |
Fever Splenomegally Hepatomegally Epistaxis |
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What are the three type of lesion seen in post kala azar dermal leishmaniasis |
Depigmented macule Erythromatous patches Erythromatus patches and depigmented macule |
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What are the causes anemia in leishmaniasis |
Hypersplenism Inflitration of the bone marrow Autoantibodies to rbc's may contribute to haemolysis |
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Anemia is accompanied what other feature |
Neutropenia Thrombocytopenia Polyclonal hypergammaglobinemia |
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What are the diagnosis |
1.Microscopy staining such as giemsa leishman or wright can demostrate amastigote within macrophage 2.Culture 3.Animal inoculation 4.Serological test(specific or non specific )
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What is the media for culturing of leishmania |
novy mcneal nicolle (NNN) |
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Which animal is used in inoculation |
Hamster |
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What is the standard Treatment |
Pentavalent antimonal sodium stibogluconate Aminoglycoside Pentamidine Meltefosine |
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What are the prevention |
Treating all cases Eradication of vector sandfly Personal prophylaxis by using antisandfly measure |
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What are the parasite producing old world cutaneous leishmaniasis |
L.major ,L.tropica,L.ethiopica |
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What are the parasite responsible for new world cutaneous leishmaniasis |
L.braziliensis,l.mexicana of south and north americal |
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What are the three distinct pattern of cutaneous leishmaniasis |
Athropotic urban Zoonotic rural type Non ulcerative and often diffused |
