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54 Cards in this Set

  • Front
  • Back

What are mood disorders?

Depressive disorders


Bipolar disorders

What are anxiety disorders?

Screening for PTSD

What is the definition of depression?

Unipolar mood disorder causing significant distress & impairment in functioning

Does depression occur with or without mania or hypomania?

WITHOUT

What is the familial association with depression?

STRONG


1.5-3 times more common than than the general population if st degree relative has diagnosis




Major depressive disorder


(MDD)

Most common


must meet criteria



Dysthymic disorder


a.ka.


Chronic persistent depressive disorder

chronic


symptoms present for more days than not


in a 2 year period

In order to be diagnosed with major depression, what is the diagnostic criteria?

At least 5 symptoms must be present during a 2 week period


&


represent a change from previous functioning

What are the major depression diagnostic criteria?

+Depressed mood


+loss or interest or pleasure in most activities (anhedonia)


+significant weight loss/gain or appetite change


+insomnia/hypersomnia


+psychomotor agitation or retardation


+loss of energy or fatigue


+feelings of worthless or excessive guilt


+diminished concentration or indecisiveness


+recurrent thoughts of suicide or death


+impaired social, occupational or other functioning

What are the neurotransmitters that make up the neurobiological changes associated with depression?

DEPLETION or DEFICIENCY


Serotonin


Norepinephrine


Dopamine





What is the basis of pharmacological treatment of depression?

Manage the relationship between the synaptic levels of neurotransmitters




Serotonin


Norepinephrine


Dopamine

What changes in the hypothalamus may lead to depression?

Pituitary - Adrenal axis dyregulation


Increased levels of corticotrophin releasing factor and cortisol

What areas of the brain have shown structural and metabolic differences in a depressed brain?

Hippocampus


Amygdala


Prefrontal cortex



What parts of the clinical presentation of a depressed person require careful attention?

AFFECT (intense, constricted)


MOOD (frustration, sadness)


SPEECH (soft, low, lack of spontaneity)




tearful, poor eye contact, inattention to personal appearance

Before referring a suicidal patient for emergency psychiatric evaluation, what FOUR questions should be asked?

1. Do you ever think of hurting yourself or ending your own life?


2. Do you find yourself dwelling on these thoughts?


3. Do you feel that you might act on these thoughts?


4. Do you have a plan?



What are suicide risk factors?

H/O prior attempt


stressful life events


social isolation


substance abuse


helplessness

What is considered suicide - low risk and what is the plan of action?

No current thoughts


No major risk factors




Action:


continue follow up visits & monitoring

What is considered suicide - intermediate risk and what is the plan of action?

Current thoughts but NO PLAN


with or without risk factors




Action:


Assess suicide risk carefully at each visit


Contract w/ pt to call if suicide thoughts become more prominent


consult with an expert as needed

What is considered suicide - high risk and what is the plan of action?

Current thoughts WITH PLAN




Action:


emergency management by qualified expert

Which patient populations are referred for management of depression?

SUICIDAL PATIENTS


PREGNANT PATIENTS


TREATMENT FAILURES

For the management of depression, what medical causes need to be ruled out?

- HYPOTHYROID

- HYPOXIA


- HYPO-PARATHYROIDISM


- B12 DEFICIENCY


- DEMENTIA


- HYPO-ADRENOCORTICISM


- MEDICATION EFFECT




What is bipolar disorder?

vacillation between depression & mania


characterized by 1 or more manic episodes

What is the presentation of bipolar disorder?

age of onset 15-30 yr


affects men & women equally


2/3 also have substance abuse disorder



What are characteristics of mania in bipolar disorder?

--heightened mood, sexuality, impulsivity


--increased energy, decreased need for sleep, faster speech & physical activity


--increased irritability, paranoia, suspicion possible



What are characteristics of hypomania in bipolar disorder?

--euphoric mood


--self confident


--increased productivity, creativity, energy

What parts of the clinical presentation of bipolar mania require careful attention?

-Cognition & perception may become psychotic


-delusions & hallucinations


-patients highly distracted


-flight of ideas


-behavior bizarre, inappropriate, disorganized


-suicidal or homicidal (violent, destructive)



What parts of the clinical presentation of bipolar depressive episode require careful attention?

- decreased pleasure, slow speech, energy, thoughts, sexuality


- mood negative, pessimistic


- patient irritable, paranoid, angry


- depression simple or psychotic


- may have suicidal thoughts


-psychotic depression - mood congruent hallucinations & delusions

What parts of the clinical presentation of bipolar manic symptoms require persistent questioning?

- inflated self esteem or grandiosity


-decreased need for sleep


-more talkative/pressure to keep talking


-flight of ideas or racing thoughts


-distractibilty


-increased goal directed activity or psychomotor agitation


-excessive pleasurable activities, painful consequences

What is assessed in bipolar 1?

Mania



What is assessed in bipolar 2?

Hypomania

Is anxiety a normal human emotion?

YES


part of fear response


fight or flight

What distinguished anxiety disorder from fear or normal anxiety?

mental tension that interfere with daily function


anxious most of the time, without apparent reason


accompanied by physical distress


fear response DOES NOT occur to a real event threatening event

LIST ANXIETY DISORDERS

GAD - Generalized anxiety disorder


PTSD - Post traumatic stress disorder


OCD - Obsessive compulsive disorder


Specific phobia


Panic disorder


Social phobia

What is the definition of Generalized Anxiety Disorder?

Excessive worry about several areas of life


associated with multiple symptoms (physical and psychological)


Causes great distress or impairment of social or occupational functioning


occurs nearly every day for at least 6 months

What are the diagnostic criteria to meet for Generalized Anxiety Disorder diagnosis?

Restlessness


Fatigue


Difficulty concentrating


Irritability


Muscle tension


Difficulty initiating sleep



What is panic disorder?

Anxiety disorder


exists with and without agoraphobia


panic attacks

What are panic attacks?

Sudden onset of intense fear or terror


with feelings of impending doom


Symptoms usually peaks within 10 minutes

What is obsessive compulsive disorder?

Anxiety Disorder


Obsessions


Compulsions

What are obsessions?

persistent intrusive thoughts



What are compulsions?

Repetitive behaviors or mental acts a person is compelled to perform


Intended to reduced anxiety

What is specific vs. social phobia?

Anxiety disorder


excessive & persistent fear of certain objects or situations to cause avoidance of trigger


vs.


excessive anxiety provoked by performance or social situations

What is the difference between acute stress disorder and PTSD?

length of time




within 1 month of event


vs


duration longer than 1 month (>3 month chronic)

What are similarities of PTSD & acute stress disorder?

persistent feeling of re-living traumatic event i.e. dreams, images




intense psychological distress, physiological re-activity, general hyper-vigilance

In anxiety clinical presentation, what are subjective key words to pay attention to?

- Tense


- Uptight


- Nervous


- Anxious


- Dread


- Jumpy

In anxiety clinical presentation, what are objective signs to pay attention to?

- Tachycardia


- Hyperventilation


- Palpitations


- Tremors


- Sweating


- Hyper-reflexia


- Increased muscle tension`

What are important diagnoses to rule out before an anxiety disorder diagnosis?

Thyrotoxicosis


Alcohol withdrawal


Abuse of sympathomimetic drugs


(caffeine, amphetamines, cocaine)


Hypoglycemia

What diagnostic testing would be done before a diagnosis of anxiety disorder?

HADS (Hospital Anxiety and Depression Scale)




Labs: TSH, EKG

If patient answers yes to any 3 items in the 4 item screen for Primary Care PTSD Screen, is this a positive screen?

YES

What is the definition of alcoholism?

Recurrent maladaptive drinking that is difficult to control and results in adverse consequences




a progressive disease affecting:


1)family 2)health 3)employment

What are the CAGE screening questions for alcohol abuse (2 or more = positive screen)?

have you ever felt you ought to...Cut down on your drinking?


Have people...Annoyed you by criticizing your drinking?


Have you ever felt bad or...Guilty about your drinking?


Have you ever had an...Eye-opener drink first thing in the morning?

What is a good introductory question for alcohol abuse screening?

I am concerned about your health and safety when I hear that you are drinking every day

List subjective symptoms that may be present in alcohol abuse evaluation

Psychological - Emotional - Behavioral


-poor nutrition


-trauma


-seizures


-hypertension


-dyspepsia


-liver disease


-pancreatitis


-peripheral neuropathy

List objective symptoms that may be present in alcohol abuse evaluation

-autonomic hyperactivity
-agitation


-hallucinations


-disorientation


-seizures



What lab diagnostics may be seen with alcohol abuse?

CBC - MCV elevation / impaired folate levels


LFT - rise in ALT and AST = ratio AST:ALT >1


GGT - returns to normal after 3 wks sober (abstinence tracker)