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12 Cards in this Set

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Volume of fluid accumulation necessary to become clinically evident in pleural effustion


- detectable on x-ray

500ml


- 200ml

Clinical features of pleural effusion

- dyspnoea


- pleuritic chest pain


- tracheal deviation: away from effusion


- decreased chest wall expansion


- stony dullness on percussion


- decreased air entry


- bronchial breathing: above effusion

7

CXR in pleural effusion

- blunting of the costophrenic angles


- dense shadows with a meniscus


- mediastinal shift away

3

Diagnosis of pleural effusion (4+6)

US-guided pleural aspiration/biopsy


- colour


- biochemistry (LDH, protein, pH, glucose, triglycerides, amylase)


- cytology


- culture & gram stain: auramine stain, TB culture


- immunology: ANA, complement

5 (2:6)

Light's criteria

Exudate


- pleural fluid protein: serum protein ratio >0.5


- pleural fluid LDH: serum LDH ratio > 0.6


- pleural fluid LDH > 2/3 ULN serum LDH

3

Transudate


- pathophysiology


- contents

- increased hydrostatic pressure, decreased oncotic pressure


- protein < 30g/l, LDH < 200IU/l

Causes of transudates

- HF (90%)


- constrictive pericarditis


- hypoproteinaemia (liver failure, nephrotic syndrome, malnutrition)


- hypothyroidism


- uncommon: Meig's syndrome (ovarian tumour)

5

Exudate


- pathophysiology


- contents

- increased vascular injury (inflammation/injury)


- protein > 30g/l, LDH > 200IU/l

Causes of exudate

- infection: bacterial pneumonia, TB


- inflammation: acute pancreatitis


- infarction: PE


- malignancy: carcinoma of the bronchus, mesothelioma, lymphoma


- uncommon: connective tissue disorders (SLE, RA), myxoedema

5

Management of pleural effusion


- complications

Thoracocentesis, aka pleural tap


- re-expansion pulmonary oedema (1.5l at first, then 1l every 8hrs)



Parapneumonic effusions types

- uncomplicated: sterile pleural fluid, normal pH & glucose, treated with ABx


- complicated: bacteria, low pH & glucose, chest drain ABx


- empyema

3

Empyema


- types


- clinical features (8)


- investigation


- management

- single collection, loculated


- persistent/recurrent pyrexia, rigors, sweating, malaise, weight loss, pleural pain, dyspnoea, productive cough


- US/CT


- large intercostal tube, ABx for 2-4wks