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12 Cards in this Set
- Front
- Back
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Platyhelminths - classification
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Phyla of helminths (other is nematoda - roundworms)
Two classes - cestoda (tapeworms) and trematoda (flukes) |
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Flukes (trematodes)
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Parasitic; obligate snail intermediate host
Water-borne infections - can also have food-borne infection w/ fish/crab as second intermediate host |
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Schistosomiasis - three major species and the disease they cause
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mansoni/japonicum - intestinal, biliary
haematobium - urinary tract, squamous cell carcinoma of bladder, renal failure, female urogenital disease |
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S. japonicum - geography, snail vector
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East/SE Asia - oncomelania
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S. mansoni - geography, snail vector
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Africa, S. America, Caribbean - biomphalaria
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S. haematobium - geography, snail vector
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Africa, Middle East - bulinus
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Schistosoma - life cycle
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1) cercaria pierce skin, enter host
2)lose tail, enter afferent circulation, become schistosomula 3)IVC --> right heart --> through pulmonary capillary bed --> pulmonary vein --> left heart --> anywhere Not hermaphrodites Egg has spine - can enter gut/bladder, go out w/ urine or feces |
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Schistosoma - pathology
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Some eggs can pierce serosa and exit, some get stuck --> inflammatory granuloma (wall of gut, bladder, liver)
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Schistosoma - who gets infected
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high rate/intensity in school kids, adolescents (esp. adolescent girls)
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S. mansoni - geography, clinical features
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Africa, S. America, Caribbean
Intestinal, liver granulomas/fibrosis Bloody diarrhea Kids livers resemble alcoholics; can get esophageal varices, ascites |
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S. japonicum - geography, clinical features
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East/SE Asia (in China - have water buffalo as reservoir)
Liver disease, hepatomegaly, ascites Can get serum sickness from schistosomula - fever, fatigue, lymphadenopathy |
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S. haematobium - geography, clinical features
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Africa, Middle East
Urinary granulomas Hematuria Obstructive uropathy Renal failure Squamous cell carcinoma of bladder Growth stunting |
