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8 Cards in this Set

  • Front
  • Back
What is ACTH?
Adrenocorticotrophic hormone
origen is the anterior pituitary gland(basophil cell)
structure is polypeptide
It is regulated by corticotropin releasing hormone(CRH) from hypothalamus.
What is Cushing's disease/
it refers to the clinical effects of increased ACTH secretion and secondarily increased adrenal corticosteroid production from a pituitary tumor.
What is Cushing's syndrome?
It is a broader term referring to the results of excess corticosteroids, whether it is due to a primary oversecretion by the pituitary or adrenal or chronic administration of corticosteroids(most common cause)
What is Addison's disease?
Most cases result from destruction of the adrenal cortex. Lack of aldosterone results in fluid loss that may cause hypotension, shock or death. Hyponatremia and hyperkalemia and acidosis from inability of sodium to be reabsorbed in the kidney in exchange for H+.
LH and FSH originate where?
Anterior pituitary gland(basophil cells)
GnRH is a releasing hormone for both LH and FSH.
In males, GnRH is regulated by negative feedback from blood levels of testosterone. TRUE/FALSE
TRUE. Spermatogenesis is believed to decrease FSH secretion in the pituitary through inhibin, a protein hormone, produced by the sertoli cells of the testes.
Inhibin is produced where in females?
The corpus luteum and together with estrogen and progesterone inhibit the production of LH and FSH through interactions with the pituitary and hypothalamus glands.
In males, LH stimulates testosterone synthesis in the testes Leydig cells, whereas FSH stimulates Spermatogenesis facilitated by testes sertoli cells. TRUE/FALSE
TRUE. The Sertoli cells do not actually produce sperm but facilitate the transformation of spermatids to spermatozoa. Further maturation and motility of the spermatozoa occur on contact with the fluids of the epididymis, vas deferens, seminal vesicles, prostate gland and bulbourethral glands.